Question 1

Glycine condenses with succinyl CoA in the first step of ____________ synthesis.

Accepted Answer

A)  thiamine 
B)  histamine 
C)  glutathione 
D)  porphyrin 
E)  folate 
A)  thiamine 
B)  histamine 
C)  glutathione 
D)  porphyrin 
E)  folate

Question 2

Although nitrogen is abundant in the form of atmospheric nitrogen,it presents a fundamental problem for use in biological systems.What is the problem,and how is it resolved?

Accepted Answer

N₂ is a remarkably inert molecule and so

Question 3

The protein ________________stores iron,whereas the protein transferrin transports it.

Accepted Answer

The answer of The protein ________________stores iron,whereas the protein transferrin...

Question 4

S-Adenosylmethionine carries _______________groups.

Accepted Answer

A)  methyl 
B)  CO2 
C)  ammonia 
D)  formyl 
E)  None of the answers is correct. 
A)  methyl 
B)  CO2 
C)  ammonia 
D)  formyl 
E)  None of the answers is correct.

Question 5

The peptide glutathione

Accepted Answer

A)  has a glutamate residue linked to glycine through its α-amine. 
B)  plays a role in the synthesis of the purine guanine. 
C)  is required to catalyze the transamination of glutamate from α-ketoglutarate. 
D)  is used to detoxify cells by reacting with organic peroxides. 
E)  functions as a one-carbon transfer molecule. 
A)  has a glutamate residue linked to glycine through its α-amine. 
B)  plays a role in the synthesis of the purine guanine. 
C)  is required to catalyze the transamination of glutamate from α-ketoglutarate. 
D)  is used to detoxify cells by reacting with organic peroxides. 
E)  functions as a one-carbon transfer molecule.

Question 6

What common biochemical strategy allows ammonia to be generated for use within the same enzyme?

Accepted Answer

A)  ammonia fixation 
B)  glutamine hydrolysis 
C)  ammonia activation 
D)  glutamate hydrolysis 
E)  None of the answers is correct. 
A)  ammonia fixation 
B)  glutamine hydrolysis 
C)  ammonia activation 
D)  glutamate hydrolysis 
E)  None of the answers is correct.

Question 7

Nitric oxide

Accepted Answer

A)  is a short-lived signal molecule. 
B)  is generated by the oxidation of lysine. 
C)  requires NADP+ and O2 for synthesis. 
D)  is metabolized be reaction with ornithine. 
E)  All of the answers are correct. 
A)  is a short-lived signal molecule. 
B)  is generated by the oxidation of lysine. 
C)  requires NADP+ and O2 for synthesis. 
D)  is metabolized be reaction with ornithine. 
E)  All of the answers are correct.

Question 8

The α-amino group found in most amino acids comes from _______________by a transamination reaction.

Accepted Answer

The answer of The α-amino group found in most amino...

Question 9

The ATP-binding region of the nitrogen-fixating reductase is a(n)___________ domain.

Accepted Answer

A)  iron-sulfur 
B)  electron-binding 
C)  P-loop NTPase family 
D)  molybdenum-binding 
E)  All the answers are correct. 
A)  iron-sulfur 
B)  electron-binding 
C)  P-loop NTPase family 
D)  molybdenum-binding 
E)  All the answers are correct.

Question 10

Tyrosine is a precursor to the molecule(s)

Accepted Answer

A)  melanin. 
B)  epinephrine. 
C)  serotonin. 
D)  melanin and epinephrine 
E)  melanin and serotonin. 
A)  melanin. 
B)  epinephrine. 
C)  serotonin. 
D)  melanin and epinephrine 
E)  melanin and serotonin.

Question 11

What caused the "madness" of King George III?

Accepted Answer

It is believed that he suffered from a p

Question 12

At least _____________ ATP molecules are hydrolyzed for each N2 reduced.

Accepted Answer

Question 13

The _______________ reaction establishes the stereochemistry at the α-carbon atom in amino acids.

Accepted Answer

The answer of The _______________ reaction establishes the stereochemistry at...

Question 14

Homocysteine is an intermediate in the synthesis of cysteine and _______________.

Accepted Answer

The answer of Homocysteine is an intermediate in the synthesis...

Question 15

The enzyme _______________ contains a selenium analogue of cysteine.

Accepted Answer

glutathion

Question 16

Glutamate is the carbon skeleton precursor for the amino acids glutamine,proline,and ______________.

Accepted Answer

The answer of Glutamate is the carbon skeleton precursor for...

Question 17

What vitamin is the precursor for methylcobalamin?

Accepted Answer

A)  B2 
B)  B6 
C)  B7 
D)  B9 
E)  B12 
A)  B2 
B)  B6 
C)  B7 
D)  B9 
E)  B12

Question 18

Methyl,methylene,and _______________ units can be carried by tetrahydrofolate.

Accepted Answer

The answer of Methyl,methylene,and _______________ units can be carried by...

Question 19

The enzyme _______________ is regulated by cumulative feedback inhibition.

Accepted Answer

glutamine

Question 20

Describe the regulation of the enzyme threonine deaminase.

Accepted Answer

This enzyme is inhibited by isoleucine,a

Exam 24: The Biosynthesis of Amino Acids

Glycine condenses with succinyl CoA in the first step of ____________ synthesis.

Although nitrogen is abundant in the form of atmospheric nitrogen,it presents a fundamental problem for use in biological systems.What is the problem,and how is it resolved?

The protein ________________stores iron,whereas the protein transferrin transports it.

S-Adenosylmethionine carries _______________groups.

The peptide glutathione

What common biochemical strategy allows ammonia to be generated for use within the same enzyme?

Nitric oxide

The α-amino group found in most amino acids comes from _______________by a transamination reaction.

The ATP-binding region of the nitrogen-fixating reductase is a(n)___________ domain.

Tyrosine is a precursor to the molecule(s)

What caused the "madness" of King George III?

At least _____________ ATP molecules are hydrolyzed for each N2 reduced.

The _______________ reaction establishes the stereochemistry at the α-carbon atom in amino acids.

Homocysteine is an intermediate in the synthesis of cysteine and _______________.

The enzyme _______________ contains a selenium analogue of cysteine.

Glutamate is the carbon skeleton precursor for the amino acids glutamine,proline,and ______________.

What vitamin is the precursor for methylcobalamin?

Methyl,methylene,and _______________ units can be carried by tetrahydrofolate.

The enzyme _______________ is regulated by cumulative feedback inhibition.

Describe the regulation of the enzyme threonine deaminase.

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

At least _____________ ATP molecules are hydrolyzed for each N₂ reduced.