Question 1

Which of the following citric acid cycle intermediates is found at the traditional start and finish of the cycle?

Accepted Answer

A)  citrate 
B)  isocitrate 
C)  $\alpha$-ketoglutarate 
D)  succinate 
E)  oxaloacetate 
A)  citrate 
B)  isocitrate 
C)  $\alpha$-ketoglutarate 
D)  succinate 
E)  oxaloacetate

Question 2

Carbons from carbohydrates enter the citric acid cycle in the form of _______________.

Accepted Answer

The answer of Carbons from carbohydrates enter the citric acid...

Question 3

In the citric acid cycle,one __________ is produced by a substrate-level phosphorylation.

Accepted Answer

The answer of In the citric acid cycle,one __________ is...

Question 4

Which of the following conditions will activate pyruvate dehydrogenase kinase,which catalyzes the phosphorylation and inactivation of E1 in the pyruvate dehydrogenase complex?

Accepted Answer

A)  elevated concentrations of NADH and ATP 
B)  elevated concentrations of NAD+ and ADP 
C)  Ca2+ 
D)  glucagon 
E)  elevated concentrations of coenzyme A 
A)  elevated concentrations of NADH and ATP 
B)  elevated concentrations of NAD+ and ADP 
C)  Ca2+ 
D)  glucagon 
E)  elevated concentrations of coenzyme A

Question 5

Formation of citrate from acetyl CoA and oxaloacetate is a(n)_________ reaction.

Accepted Answer

A)  oxidation 
B)  reduction 
C)  condensation 
D)  ligation 
E)  None of the answers is correct. 
A)  oxidation 
B)  reduction 
C)  condensation 
D)  ligation 
E)  None of the answers is correct.

Question 6

Starting with oxaloacetate in the glyoxylate cycle,identify what molecules enter and exit the glyoxylate cycle.

Accepted Answer

The cycle begins with the condensation o

Question 7

List the five coenzymes that are required for the oxidative decarboxylation of pyruvate and α-ketoglutarate,and give the essential nutrient (vitamin)that is required for each.

Accepted Answer

1.Thiamine pyrophosphate: thia

Question 8

Which of the following is toxic due to its ability to react with neighboring sulfhydryls of dihydrolipoyl groups,thus blocking their reoxidation to lipoamide?

Accepted Answer

A)  fluoroacetate 
B)  carbon monoxide 
C)  arsenite 
D)  rotenone 
E)  cyanide 
A)  fluoroacetate 
B)  carbon monoxide 
C)  arsenite 
D)  rotenone 
E)  cyanide

Exam 17: The Citric Acid Cycle

Which of the following citric acid cycle intermediates is found at the traditional start and finish of the cycle?

Carbons from carbohydrates enter the citric acid cycle in the form of _______________.

In the citric acid cycle,one __________ is produced by a substrate-level phosphorylation.

Which of the following conditions will activate pyruvate dehydrogenase kinase,which catalyzes the phosphorylation and inactivation of E1 in the pyruvate dehydrogenase complex?

Formation of citrate from acetyl CoA and oxaloacetate is a(n)_________ reaction.

Starting with oxaloacetate in the glyoxylate cycle,identify what molecules enter and exit the glyoxylate cycle.

List the five coenzymes that are required for the oxidative decarboxylation of pyruvate and α-ketoglutarate,and give the essential nutrient (vitamin)that is required for each.

Which of the following is toxic due to its ability to react with neighboring sulfhydryls of dihydrolipoyl groups,thus blocking their reoxidation to lipoamide?

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

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Which of the following conditions will activate pyruvate dehydrogenase kinase,which catalyzes the phosphorylation and inactivation of E₁ in the pyruvate dehydrogenase complex?