Question 1

During the M checkpoint,the cell ____.

Accepted Answer

A)  proceeds to interphase and completes DNA replication 
B)  proceeds to G2 phase and the cell prepares to divide 
C)  proceeds to S phase or enters inactive G0 state 
D)  monitors attachment of spindle fibers to chromosomes 
E)  monitors completion of DNA synthesis and DNA damage 
A)  proceeds to interphase and completes DNA replication 
B)  proceeds to G2 phase and the cell prepares to divide 
C)  proceeds to S phase or enters inactive G0 state 
D)  monitors attachment of spindle fibers to chromosomes 
E)  monitors completion of DNA synthesis and DNA damage

Question 2

With the sequence of the gene-coding regions of the human genome in hand and the development of newer sequencing methods,scientists ____.

Accepted Answer

A)  now know that the types of mutations present in all cancers are very similar 
B)  can now sequence and analyze the protein-coding genes in cancer cells 
C)  are still unable to systematically identify all the mutations present in a cancer cell 
D)  found that the number of mutational events that occur during the transition from normal to malignant cells is much smaller than previously thought 
E)  found that most tumors had at least 100 mutations in common with any other tumor, emphasizing the common origin of cancer 
A)  now know that the types of mutations present in all cancers are very similar 
B)  can now sequence and analyze the protein-coding genes in cancer cells 
C)  are still unable to systematically identify all the mutations present in a cancer cell 
D)  found that the number of mutational events that occur during the transition from normal to malignant cells is much smaller than previously thought 
E)  found that most tumors had at least 100 mutations in common with any other tumor, emphasizing the common origin of cancer

Question 3

The cancer drugs Gleevec and Herceptin bind to receptor ____________________ and stop the growth of cancer cells.

Accepted Answer

The answer of The cancer drugs Gleevec and Herceptin bind...

Question 4

Outline the four characteristics of cancer.

Accepted Answer

The four characteristics of cancer are t

Question 5

In some families,members inherit a mutant allele that causes a(n)____________________ to cancer.

Accepted Answer

The answer of In some families,members inherit a mutant allele...

Question 6

A proto-oncogene ____.

Accepted Answer

A)  always becomes cancerous 
B)  causes cancer 
C)  encodes tumor-suppressing proteins 
D)  repairs DNA 
E)  regulates cell division 
A)  always becomes cancerous 
B)  causes cancer 
C)  encodes tumor-suppressing proteins 
D)  repairs DNA 
E)  regulates cell division

Question 7

In most cases,cancer-causing mutations ____.

Accepted Answer

A)  accumulate over a number of years 
B)  accumulate very quickly within a single cell 
C)  metastasize within a short time 
D)  must all occur on the q arm of a chromosome 
E)  occur during the G0 phase of the cell cycle 
A)  accumulate over a number of years 
B)  accumulate very quickly within a single cell 
C)  metastasize within a short time 
D)  must all occur on the q arm of a chromosome 
E)  occur during the G0 phase of the cell cycle

Question 8

List three properties that all forms of cancers share and summarize the origin of these properties.

Accepted Answer

The three properties that all forms of c

Question 9

The ras proto-oncogene family is a group of related genes that slow or stop the progression of cancer.

Accepted Answer

A) True 
 B)False

Question 10

In the atmosphere,____________________depletion in certain regions of the globe contributes to increased levels of UV radiation exposure,which in turn is associated with increases in skin cancer frequency.

Accepted Answer

The answer of In the atmosphere,____________________depletion in certain regions of...

Question 11

Outline the two parts of the eukaryotic cell cycle and describe the three main checkpoints in cell cycle regulation.

Accepted Answer

The eukaryotic cell cycle consists of tw

Question 12

BRCA2 maps to the long arm of chromosome 13 and may be responsible for the majority of inherited predispositions for breast cancer not caused by ____________________.

Accepted Answer

The answer of BRCA2 maps to the long arm of...

Question 13

Outline the three criteria recommended by the American Society of Clinical Oncology (ASCO)for when cancer tests should be done.

Accepted Answer

The ASCO recommends that cancer tests sh

Question 14

Mutant forms of proto-oncogenes are called ____________________.

Accepted Answer

The answer of Mutant forms of proto-oncogenes are called ____________________....

Question 15

All epithelial cells in the inner lining of the large intestine that are heterozygous for an APC mutation ____.

Accepted Answer

A)  are able to control cell division with the second copy of the APC gene 
B)  become cancerous 
C)  require additional mutations in downstream genes to become cancerous 
D)  cause the transition from polyps into colon cancer 
E)  can partially escape control of the cell cycle and lead to the formation of clusters of polyps 
A)  are able to control cell division with the second copy of the APC gene 
B)  become cancerous 
C)  require additional mutations in downstream genes to become cancerous 
D)  cause the transition from polyps into colon cancer 
E)  can partially escape control of the cell cycle and lead to the formation of clusters of polyps

Question 16

The translocation seen in the Philadelphia chromosome in myelogenous leukemia represents ____.

Accepted Answer

A)  a chromosomal aberration that is secondary to the cancer 
B)  a chromosomal aberration that is caused by the development of cancer 
C)  a proto-oncogene that has been deleted from chromosome 6 and inserted into chromosome 7 
D)  a specific chromosomal aberration accompanying a specific cancer 
E)  the evidence of exposure to chemical carcinogens 
A)  a chromosomal aberration that is secondary to the cancer 
B)  a chromosomal aberration that is caused by the development of cancer 
C)  a proto-oncogene that has been deleted from chromosome 6 and inserted into chromosome 7 
D)  a specific chromosomal aberration accompanying a specific cancer 
E)  the evidence of exposure to chemical carcinogens

Question 17

In the familial form of retinoblastoma,individuals who inherit one mutant allele of the RB1 gene have an 85% chance of developing retinoblastoma and other cancers.Explain why,when these individuals carry only one copy of the mutant gene,there is such a high incidence of cancer in these RB1 heterozygotes.

Accepted Answer

Those who inherit the mutant allele carr

Question 18

According to the American Cancer Society,30% of all cancer deaths in the U.S.are due to ____.

Accepted Answer

A)  ultraviolet light exposure 
B)  automobile exhaust 
C)  industrial pollutants 
D)  pesticide and herbicide exposure 
E)  smoking 
A)  ultraviolet light exposure 
B)  automobile exhaust 
C)  industrial pollutants 
D)  pesticide and herbicide exposure 
E)  smoking

Question 19

Viral infection is a major cause of cancer.

Accepted Answer

A) True 
 B)False

Question 20

About one in three people will be diagnosed with cancer at some time in his/her life.

Accepted Answer

A) True 
 B)False

During the M checkpoint,the cell ____.

With the sequence of the gene-coding regions of the human genome in hand and the development of newer sequencing methods,scientists ____.

The cancer drugs Gleevec and Herceptin bind to receptor ____________________ and stop the growth of cancer cells.

Outline the four characteristics of cancer.

In some families,members inherit a mutant allele that causes a(n)____________________ to cancer.

A proto-oncogene ____.

In most cases,cancer-causing mutations ____.

List three properties that all forms of cancers share and summarize the origin of these properties.

The ras proto-oncogene family is a group of related genes that slow or stop the progression of cancer.

In the atmosphere,____________________depletion in certain regions of the globe contributes to increased levels of UV radiation exposure,which in turn is associated with increases in skin cancer frequency.

Outline the two parts of the eukaryotic cell cycle and describe the three main checkpoints in cell cycle regulation.

BRCA2 maps to the long arm of chromosome 13 and may be responsible for the majority of inherited predispositions for breast cancer not caused by ____________________.

Outline the three criteria recommended by the American Society of Clinical Oncology (ASCO)for when cancer tests should be done.

Mutant forms of proto-oncogenes are called ____________________.

All epithelial cells in the inner lining of the large intestine that are heterozygous for an APC mutation ____.

The translocation seen in the Philadelphia chromosome in myelogenous leukemia represents ____.

According to the American Cancer Society,30% of all cancer deaths in the U.S.are due to ____.

Viral infection is a major cause of cancer.

About one in three people will be diagnosed with cancer at some time in his/her life.

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes from Generation to Generation

Pedigree Analysis in Human Genetics

The Inheritance of Complex Traits

Cytogenetics - Karyotypes and Chromosome Aberrations

Development and Sex Determination

The Structure - Replication - and Chromosomal Organization of DNA

Gene Expression and Gene Regulation

From Proteins to Phenotypes

Genome Alterations - Mutation and Epigenetics

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology - Genetic Testing - and Gene Therapy

Genes and The Immune System

Genetics of Behavior

Population Genetics and Human Evolution

Filters

Exam 12: Genes and Cancer

During the M checkpoint,the cell ____.

With the sequence of the gene-coding regions of the human genome in hand and the development of newer sequencing methods,scientists ____.

The cancer drugs Gleevec and Herceptin bind to receptor ____________________ and stop the growth of cancer cells.

Outline the four characteristics of cancer.

In some families,members inherit a mutant allele that causes a(n)____________________ to cancer.

A proto-oncogene ____.

In most cases,cancer-causing mutations ____.

List three properties that all forms of cancers share and summarize the origin of these properties.

The ras proto-oncogene family is a group of related genes that slow or stop the progression of cancer.

In the atmosphere,____________________depletion in certain regions of the globe contributes to increased levels of UV radiation exposure,which in turn is associated with increases in skin cancer frequency.

Outline the two parts of the eukaryotic cell cycle and describe the three main checkpoints in cell cycle regulation.

BRCA2 maps to the long arm of chromosome 13 and may be responsible for the majority of inherited predispositions for breast cancer not caused by ____________________.

Outline the three criteria recommended by the American Society of Clinical Oncology (ASCO)for when cancer tests should be done.

Mutant forms of proto-oncogenes are called ____________________.

All epithelial cells in the inner lining of the large intestine that are heterozygous for an APC mutation ____.

The translocation seen in the Philadelphia chromosome in myelogenous leukemia represents ____.

According to the American Cancer Society,30% of all cancer deaths in the U.S.are due to ____.

Viral infection is a major cause of cancer.

About one in three people will be diagnosed with cancer at some time in his/her life.

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes from Generation to Generation

Pedigree Analysis in Human Genetics

The Inheritance of Complex Traits

Cytogenetics - Karyotypes and Chromosome Aberrations

Development and Sex Determination

The Structure - Replication - and Chromosomal Organization of DNA

Gene Expression and Gene Regulation

From Proteins to Phenotypes

Genome Alterations - Mutation and Epigenetics

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology - Genetic Testing - and Gene Therapy

Genes and The Immune System

Genetics of Behavior

Population Genetics and Human Evolution

Filters