Question 1

Which of the following is true of the relation between drug affinity and drug effects?

Accepted Answer

A)  A drug with high affinity for a receptor will exert an effect only at a very high dose. 
B)  Drug affinity does not relate to drug activity. 
C)  A drug with high affinity for a receptor will exert an effect at a low dose. 
D)  A drug with a low affinity for a receptor will exert an effect only at a very low dose. 
E)  A drug that has a potent behavioral effect will have a low affinity for its receptor. 
A)  A drug with high affinity for a receptor will exert an effect only at a very high dose. 
B)  Drug affinity does not relate to drug activity. 
C)  A drug with high affinity for a receptor will exert an effect at a low dose. 
D)  A drug with a low affinity for a receptor will exert an effect only at a very low dose. 
E)  A drug that has a potent behavioral effect will have a low affinity for its receptor.

Question 2

Describe the major functions of glutamate in neurotransmission.

Accepted Answer

Glutamate is the primary excitatory amin

Question 3

Match the drug with its correct action on GABA function.

Accepted Answer

A)  muscimol; direct agonist at the GABAA receptor 
B)  picrotoxin; indirect antagonist of the GABAB receptor 
C)  diazepam; indirect antagonist of GABAA receptors 
D)  baclofen; antagonist at the GABAA receptor 
E)  THC ; agonist at the GABAA receptor 
A)  muscimol; direct agonist at the GABAA receptor 
B)  picrotoxin; indirect antagonist of the GABAB receptor 
C)  diazepam; indirect antagonist of GABAA receptors 
D)  baclofen; antagonist at the GABAA receptor 
E)  THC ; agonist at the GABAA receptor

Question 4

Explain why blockade of serotonin reuptake is a common drug strategy for the treatment of certain mental disorders.

Accepted Answer

Several mental disorders are related to

Question 5

Schizophrenia is treated with drugs that block a subtype of the ________ receptor..

Accepted Answer

A)  GABA 
B)  gkycine 
C)  ACh 
D)  dopamine 
E)  Norepinephrine 
A)  GABA 
B)  gkycine 
C)  ACh 
D)  dopamine 
E)  Norepinephrine

Question 6

________ refers to the capacity of a drug molecule to bind to a receptor.

Accepted Answer

A)  Dynamic capacity 
B)  Sensitization 
C)  Inactivation 
D)  Affinity 
E)  Binding capacity 
A)  Dynamic capacity 
B)  Sensitization 
C)  Inactivation 
D)  Affinity 
E)  Binding capacity

Question 7

Parkinson's disease involves the degeneration of neurons within the ________ DA system.

Accepted Answer

A)  nigrostriatal 
B)  mesocortical 
C)  hypothalamocortical 
D)  mesolimbic 
E)  retinal-suprachiasmatic 
A)  nigrostriatal 
B)  mesocortical 
C)  hypothalamocortical 
D)  mesolimbic 
E)  retinal-suprachiasmatic

Question 8

A(n)________ is an innocuous substance that has no specific physiological effect.

Accepted Answer

A)  placebo 
B)  agonist 
C)  drug 
D)  pseudotransmitter 
E)  ligand 
A)  placebo 
B)  agonist 
C)  drug 
D)  pseudotransmitter 
E)  ligand

Question 9

Which of the following true of NMDA receptors?

Accepted Answer

A)  Activation of the NMDA receptor allows sodium and calcium ions into the nerve cell. 
B)  NMDA receptors are metabotropic. 
C)  Glutamate is an antagonist for the NMDA receptor. 
D)  The activity of the NMDA receptor is not dependent on magnesium ions. 
E)  The NMDA receptor produces IPSPs. 
A)  Activation of the NMDA receptor allows sodium and calcium ions into the nerve cell. 
B)  NMDA receptors are metabotropic. 
C)  Glutamate is an antagonist for the NMDA receptor. 
D)  The activity of the NMDA receptor is not dependent on magnesium ions. 
E)  The NMDA receptor produces IPSPs.

Question 10

________ is the primary efferent neurotransmitter secreted by efferent axons of the CNS.

Accepted Answer

A)  Dopamine 
B)  Norepinephrine 
C)  Acetylcholine 
D)  Serotonin 
E)  GABA 
A)  Dopamine 
B)  Norepinephrine 
C)  Acetylcholine 
D)  Serotonin 
E)  GABA

Question 11

Describe the four different subtypes of noradrenergic receptors in the brain.How are these receptors differentiated from one another?

Accepted Answer

Norepinephrine and epinephrine are the a

Question 12

Which of the following represents a problem for the hypothesis that amino acids can function as neurotransmitters?

Accepted Answer

A)  Amino acids can be released from nerve terminals. 
B)  EPSPs and IPSPs are produced by application of amino acids onto neurons. 
C)  Amino acids are localized within neurons. 
D)  Amino acids play a role in protein synthesis for all nerve cells. 
E)  None of the above are correct. 
A)  Amino acids can be released from nerve terminals. 
B)  EPSPs and IPSPs are produced by application of amino acids onto neurons. 
C)  Amino acids are localized within neurons. 
D)  Amino acids play a role in protein synthesis for all nerve cells. 
E)  None of the above are correct.

Question 13

Administration of a drug that binds with a postsynaptic receptor,but does not open ion channels would be termed a(n)

Accepted Answer

A)  direct agonist. 
B)  ligand. 
C)  direct synergist. 
D)  direct antagonist. 
E)  indirect pheromone. 
A)  direct agonist. 
B)  ligand. 
C)  direct synergist. 
D)  direct antagonist. 
E)  indirect pheromone.

Question 14

Withdrawal from heroin results in ________,which involves a feeling of anxious misery.

Accepted Answer

A)  euphoria 
B)  dysphoria 
C)  depression 
D)  mania 
E)  sensitization 
A)  euphoria 
B)  dysphoria 
C)  depression 
D)  mania 
E)  sensitization

Question 15

Administration of a drug that binds at a postsynaptic site different from that of the neurotransmitter,and facilitates the opening of ion channels would be termed a(n)

Accepted Answer

A)  indirect antagonist. 
B)  ligand. 
C)  direct synergist. 
D)  indirect agonist. 
E)  indirect pheromone. 
A)  indirect antagonist. 
B)  ligand. 
C)  direct synergist. 
D)  indirect agonist. 
E)  indirect pheromone.

Question 16

Withdrawal from ________ can result in seizures due to the loss of inhibitory action on ________ receptors.

Accepted Answer

A)  THC; CB2 
B)  alcohol; D1 and D2 
C)  THC; D1 and D2 
D)  MDMA; CB2 
E)  alcohol; NMDA 
A)  THC; CB2 
B)  alcohol; D1 and D2 
C)  THC; D1 and D2 
D)  MDMA; CB2 
E)  alcohol; NMDA

Question 17

Imagine that you are suffering from severe pain and that you have the opportunity to request a drug to alleviate the pain.Which of the following drugs should you ask for?

Accepted Answer

A)  an opiate that produces analgesia only at high doses 
B)  naloxone 
C)  caffeine 
D)  an opiate that produces analgesia at low doses 
E)  a drug that blocks GABA receptors 
A)  an opiate that produces analgesia only at high doses 
B)  naloxone 
C)  caffeine 
D)  an opiate that produces analgesia at low doses 
E)  a drug that blocks GABA receptors

Question 18

Repeated administration of a constant drug dose typically produces ________,which is defined as a(n)________ effect of the drug.

Accepted Answer

A)  dynamic capacity; increased 
B)  sensitization; reduced 
C)  behavioral inactivation; increased 
D)  tolerance; reduced 
E)  homeostasis; constant 
A)  dynamic capacity; increased 
B)  sensitization; reduced 
C)  behavioral inactivation; increased 
D)  tolerance; reduced 
E)  homeostasis; constant

Question 19

THC interferes with concentration and memory and can distort our sense of time.

Accepted Answer

A) True 
 B)False

Question 20

Which pair of drugs below are antagonists for the muscarinic and nicotinic (respectively)receptors?

Accepted Answer

A)  atropine; curare 
B)  hemicholium; atropine 
C)  curare; atropine 
D)  muscarine; nicotine 
E)  acetylcholinesterase; choline acetyltransferase 
A)  atropine; curare 
B)  hemicholium; atropine 
C)  curare; atropine 
D)  muscarine; nicotine 
E)  acetylcholinesterase; choline acetyltransferase

Which of the following is true of the relation between drug affinity and drug effects?

Describe the major functions of glutamate in neurotransmission.

Match the drug with its correct action on GABA function.

Explain why blockade of serotonin reuptake is a common drug strategy for the treatment of certain mental disorders.

Schizophrenia is treated with drugs that block a subtype of the ________ receptor..

________ refers to the capacity of a drug molecule to bind to a receptor.

Parkinson's disease involves the degeneration of neurons within the ________ DA system.

A(n)________ is an innocuous substance that has no specific physiological effect.

Which of the following true of NMDA receptors?

________ is the primary efferent neurotransmitter secreted by efferent axons of the CNS.

Describe the four different subtypes of noradrenergic receptors in the brain.How are these receptors differentiated from one another?

Which of the following represents a problem for the hypothesis that amino acids can function as neurotransmitters?

Administration of a drug that binds with a postsynaptic receptor,but does not open ion channels would be termed a(n)

Withdrawal from heroin results in ________,which involves a feeling of anxious misery.

Administration of a drug that binds at a postsynaptic site different from that of the neurotransmitter,and facilitates the opening of ion channels would be termed a(n)

Withdrawal from can result in seizures due to the loss of inhibitory action on receptors.

Imagine that you are suffering from severe pain and that you have the opportunity to request a drug to alleviate the pain.Which of the following drugs should you ask for?

Repeated administration of a constant drug dose typically produces ,which is defined as a(n) effect of the drug.

THC interferes with concentration and memory and can distort our sense of time.

Which pair of drugs below are antagonists for the muscarinic and nicotinic (respectively)receptors?

Origins of Behavioral Neuroscience

Structure and Functions of Cells of the Nervous System

Structure of the Nervous System

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia, Affective Disorders, and Anxiety Disorders

Autistic, Attention-Deficit/Hyperactivity, Stress, and Substance Abuse Disorders

Filters

Exam 4: Psychopharmacology

Which of the following is true of the relation between drug affinity and drug effects?

Describe the major functions of glutamate in neurotransmission.

Match the drug with its correct action on GABA function.

Explain why blockade of serotonin reuptake is a common drug strategy for the treatment of certain mental disorders.

Schizophrenia is treated with drugs that block a subtype of the ________ receptor..

________ refers to the capacity of a drug molecule to bind to a receptor.

Parkinson's disease involves the degeneration of neurons within the ________ DA system.

A(n)________ is an innocuous substance that has no specific physiological effect.

Which of the following true of NMDA receptors?

________ is the primary efferent neurotransmitter secreted by efferent axons of the CNS.

Describe the four different subtypes of noradrenergic receptors in the brain.How are these receptors differentiated from one another?

Which of the following represents a problem for the hypothesis that amino acids can function as neurotransmitters?

Administration of a drug that binds with a postsynaptic receptor,but does not open ion channels would be termed a(n)

Withdrawal from heroin results in ________,which involves a feeling of anxious misery.

Administration of a drug that binds at a postsynaptic site different from that of the neurotransmitter,and facilitates the opening of ion channels would be termed a(n)

Withdrawal from ________ can result in seizures due to the loss of inhibitory action on ________ receptors.

Imagine that you are suffering from severe pain and that you have the opportunity to request a drug to alleviate the pain.Which of the following drugs should you ask for?

Repeated administration of a constant drug dose typically produces ________,which is defined as a(n)________ effect of the drug.

THC interferes with concentration and memory and can distort our sense of time.

Which pair of drugs below are antagonists for the muscarinic and nicotinic (respectively)receptors?

Origins of Behavioral Neuroscience

Structure and Functions of Cells of the Nervous System

Structure of the Nervous System

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia, Affective Disorders, and Anxiety Disorders

Autistic, Attention-Deficit/Hyperactivity, Stress, and Substance Abuse Disorders

Filters

Withdrawal from can result in seizures due to the loss of inhibitory action on receptors.

Repeated administration of a constant drug dose typically produces ,which is defined as a(n) effect of the drug.