Question 1

Drugs are available to lower cholesterol which actually inhibit its synthesis in the body.

Accepted Answer

A) True 
 B)False

Question 2

When is propionyl-CoA carboxylase required for the complete oxidation of a fatty acid?

Accepted Answer

A)  When it has an even number of carbons. 
B)  When it has an odd number of carbons. 
C)  When it is a monounsaturated fatty acid. 
D)  When it is a polyunsaturated fatty acid. 
A)  When it has an even number of carbons. 
B)  When it has an odd number of carbons. 
C)  When it is a monounsaturated fatty acid. 
D)  When it is a polyunsaturated fatty acid.

Question 3

Reduction reactions during fatty acid synthesis utilize

Accepted Answer

A)  FADH2. 
B)  NADH. 
C)  NADPH. 
D)  FADH2 and NADH. 
E)  FADH2 and NADPH. 
A)  FADH2. 
B)  NADH. 
C)  NADPH. 
D)  FADH2 and NADH. 
E)  FADH2 and NADPH.

Question 4

Lipids yield more ATP than sugars because

Accepted Answer

A)  they have more carbon atoms than sugars. 
B)  their carbon atoms are more highly reduced. 
C)  both of these 
D)  neither of these 
A)  they have more carbon atoms than sugars. 
B)  their carbon atoms are more highly reduced. 
C)  both of these 
D)  neither of these

Question 5

The first three reactions of the b-oxidation cycle of fatty acids produce

Accepted Answer

A)  two moles of NADH 
B)  two moles of FADH2 
C)  one mole each of NADH and FADH2 
D)  two moles of ATP 
A)  two moles of NADH 
B)  two moles of FADH2 
C)  one mole each of NADH and FADH2 
D)  two moles of ATP

Question 6

The use of cyclic AMP to mobilize fatty acids from adipose tissue is analogous to cyclic AMPs role in mobilization of sugars from glycogen in the liver.

Accepted Answer

A) True 
 B)False

Question 7

The b-oxidation of unsaturated fatty acids requires additional enzymes to isomerize the double bonds.

Accepted Answer

A) True 
 B)False

Question 8

Cholesterol is a precursor of all of the following except

Accepted Answer

A)  cortisone 
B)  testosterone 
C)  progesterone 
D)  lanosterol 
A)  cortisone 
B)  testosterone 
C)  progesterone 
D)  lanosterol

Question 9

The primary function of biotin in metabolism is:

Accepted Answer

A)  to allow for the addition of CO2 to other molecules. 
B)  to inhibit acetyl-CoA carboxylase 
C)  to inhibit carnitine palmitoyltransferase 
D)  all of these 
A)  to allow for the addition of CO2 to other molecules. 
B)  to inhibit acetyl-CoA carboxylase 
C)  to inhibit carnitine palmitoyltransferase 
D)  all of these

Question 10

Other than their use in nucleic acid synthesis,which energy source is used uniquely for the synthesis of lipids?

Accepted Answer

A)  ATP 
B)  CTP 
C)  GTP 
D)  UTP 
E)  None of these is unique to fatty acid synthesis. 
A)  ATP 
B)  CTP 
C)  GTP 
D)  UTP 
E)  None of these is unique to fatty acid synthesis.

Question 11

Which of the following is true about the FTO gene and obesity?

Accepted Answer

A)  People with the FTO gene will be obese 
B)  Scientists know exactly how the FTO gene leads to obesity 
C)  Individuals with a specific variant of the FTO gene are a little over 1.5 times as likely to be obese 
D)  All of these are true 
A)  People with the FTO gene will be obese 
B)  Scientists know exactly how the FTO gene leads to obesity 
C)  Individuals with a specific variant of the FTO gene are a little over 1.5 times as likely to be obese 
D)  All of these are true

Question 12

Where in the cell does fatty acid synthesis occur?

Accepted Answer

A)  Cytoplasm. 
B)  Outer mitochondrial membrane. 
C)  Mitochondrial intermembrane space. 
D)  Inner mitochondrial membrane. 
E)  Mitochondrial matrix. 
A)  Cytoplasm. 
B)  Outer mitochondrial membrane. 
C)  Mitochondrial intermembrane space. 
D)  Inner mitochondrial membrane. 
E)  Mitochondrial matrix.

Question 13

Approximately how many ATP molecules are netted from the complete oxidation of stearic acid (C-18)?

Accepted Answer

A)  2 
B)  4 
C)  32 
D)  88 
E)  120 
A)  2 
B)  4 
C)  32 
D)  88 
E)  120

Question 14

How many NADPH are oxidized in the synthesis of palmitoyl-CoA from eight molecules of acetyl-CoA?

Accepted Answer

A)  1 
B)  7 
C)  8 
D)  14 
E)  16 
A)  1 
B)  7 
C)  8 
D)  14 
E)  16

Question 15

The bond linking a fatty acid to coenzyme A is

Accepted Answer

A)  an ester. 
B)  a thioester. 
C)  an anhydride. 
D)  an ether. 
A)  an ester. 
B)  a thioester. 
C)  an anhydride. 
D)  an ether.

Question 16

Where in the cell does b-oxidation occur?

Accepted Answer

A)  Cytoplasm. 
B)  Outer mitochondrial membrane. 
C)  Mitochondrial intermembrane space. 
D)  Inner mitochondrial membrane. 
E)  Mitochondrial matrix. 
A)  Cytoplasm. 
B)  Outer mitochondrial membrane. 
C)  Mitochondrial intermembrane space. 
D)  Inner mitochondrial membrane. 
E)  Mitochondrial matrix.

Question 17

How many ATPs can be netted from the complete oxidation of palmitate (C16) to CO2 & H2O?

Accepted Answer

A)  ATPs £ 40 
B)  40 < ATPs £ 80 
C)  80 < ATPs £ 120 
D)  1200 < ATPs 
A)  ATPs £ 40 
B)  40 < ATPs £ 80 
C)  80 < ATPs £ 120 
D)  1200 < ATPs

Question 18

Fatty acid synthase binds growing fatty acids

Accepted Answer

A)  by an ester linkage to a side chain of serine. 
B)  by a thioester linkage to a side chain of cysteines. 
C)  as a Schiff base to a side chain of lysine. 
D)  by a thioester linkage to a phosphopantetheine linked to a serine. 
A)  by an ester linkage to a side chain of serine. 
B)  by a thioester linkage to a side chain of cysteines. 
C)  as a Schiff base to a side chain of lysine. 
D)  by a thioester linkage to a phosphopantetheine linked to a serine.

Question 19

Which of the following is true concerning phospholipases?

Accepted Answer

A)  Many snake venoms contain phospholipases 
B)  Phospholipase D is a component in some spider venoms 
C)  Phospholipases in snake venoms can lead to the lysing of blood cells 
D)  All of these 
A)  Many snake venoms contain phospholipases 
B)  Phospholipase D is a component in some spider venoms 
C)  Phospholipases in snake venoms can lead to the lysing of blood cells 
D)  All of these

Question 20

Of the processes listed below,which is not an important source of acetyl-CoA?

Accepted Answer

A)  pentose phosphate pathway 
B)  amino acid degradation 
C)  glycolysis 
D)  fatty acid oxidation 
A)  pentose phosphate pathway 
B)  amino acid degradation 
C)  glycolysis 
D)  fatty acid oxidation

Exam 21: Lipid Metabolism

Drugs are available to lower cholesterol which actually inhibit its synthesis in the body.

When is propionyl-CoA carboxylase required for the complete oxidation of a fatty acid?

Reduction reactions during fatty acid synthesis utilize

Lipids yield more ATP than sugars because

The first three reactions of the b-oxidation cycle of fatty acids produce

The use of cyclic AMP to mobilize fatty acids from adipose tissue is analogous to cyclic AMPs role in mobilization of sugars from glycogen in the liver.

The b-oxidation of unsaturated fatty acids requires additional enzymes to isomerize the double bonds.

Cholesterol is a precursor of all of the following except

The primary function of biotin in metabolism is:

Other than their use in nucleic acid synthesis,which energy source is used uniquely for the synthesis of lipids?

Which of the following is true about the FTO gene and obesity?

Where in the cell does fatty acid synthesis occur?

Approximately how many ATP molecules are netted from the complete oxidation of stearic acid (C-18)?

How many NADPH are oxidized in the synthesis of palmitoyl-CoA from eight molecules of acetyl-CoA?

The bond linking a fatty acid to coenzyme A is

Where in the cell does b-oxidation occur?

How many ATPs can be netted from the complete oxidation of palmitate (C16) to CO2 & H2O?

Fatty acid synthase binds growing fatty acids

Which of the following is true concerning phospholipases?

Of the processes listed below,which is not an important source of acetyl-CoA?

Biochemistry and the Organization of Cells

Water: The Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of Rna

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

Filters

How many ATPs can be netted from the complete oxidation of palmitate (C₁₆) to CO₂ & H₂O?