Question 1

Which of the following is not associated with coronary heart disease?

Accepted Answer

A)  high relative levels of HDLs 
B)  high levels of LDLs 
C)  absence or dysfunction of LDL receptors 
D)  serum cholesterol levels of 300 mg/dl or higher 
A)  high relative levels of HDLs 
B)  high levels of LDLs 
C)  absence or dysfunction of LDL receptors 
D)  serum cholesterol levels of 300 mg/dl or higher

Question 2

The yield of ATP from oxidation of an unsaturated fatty acid has what relationship to the yield from the oxidation of a saturated fatty acid with the same number of carbon atoms?

Accepted Answer

A)  less 
B)  greater 
C)  the same 
D)  not possible to determine from the information in this chapter 
A)  less 
B)  greater 
C)  the same 
D)  not possible to determine from the information in this chapter

Question 3

Which of the following vitamins and cofactors is not used in b-oxidation?

Accepted Answer

A)  Biotin 
B)  Niacin 
C)  Pantothenic acid 
D)  Riboflavin 
E)  All of these are important in the b-oxidation of fatty acids. 
A)  Biotin 
B)  Niacin 
C)  Pantothenic acid 
D)  Riboflavin 
E)  All of these are important in the b-oxidation of fatty acids.

Question 4

Biosynthesis of compound lipids typically takes place

Accepted Answer

A)  in the mitochondrial matrix 
B)  in the cytosol 
C)  on the endoplasmic reticulum 
D)  in the Golgi apparatus 
A)  in the mitochondrial matrix 
B)  in the cytosol 
C)  on the endoplasmic reticulum 
D)  in the Golgi apparatus

Question 5

The human lipoproteins with the lowest density are

Accepted Answer

A)  Chylomicrons. 
B)  HDL. 
C)  IDL. 
D)  LDL. 
E)  VLDL. 
A)  Chylomicrons. 
B)  HDL. 
C)  IDL. 
D)  LDL. 
E)  VLDL.

Question 6

Phospholipases are designated A,B,etc,based on

Accepted Answer

A)  the different sites in the molecule where they cleave the phospholipids. 
B)  whether they are phosphorylases or hydrolases. 
C)  whether they use NAD as a cofactor. 
D)  whether they use ATP as a cofactor. 
A)  the different sites in the molecule where they cleave the phospholipids. 
B)  whether they are phosphorylases or hydrolases. 
C)  whether they use NAD as a cofactor. 
D)  whether they use ATP as a cofactor.

Question 7

The metabolically activated form of a fatty acid is

Accepted Answer

A)  an ester 
B)  a Schiff base 
C)  a phosphate ester 
D)  a thioester 
A)  an ester 
B)  a Schiff base 
C)  a phosphate ester 
D)  a thioester

Question 8

Which of the following enzyme types is involved in both fatty acid synthesis and breakdown?

Accepted Answer

A)  Carboxylase. 
B)  Transferase. 
C)  Synthase. 
D)  Both carboxylase and synthase. 
E)  All three of these enzymes are used in fatty acid synthesis. 
A)  Carboxylase. 
B)  Transferase. 
C)  Synthase. 
D)  Both carboxylase and synthase. 
E)  All three of these enzymes are used in fatty acid synthesis.

Question 9

The enzyme activity catalyzing the reaction shown is best termed a

Accepted Answer

A)  reductase 
B)  ketothiolase 
C)  transferase 
D)  dehydratase 
A)  reductase 
B)  ketothiolase 
C)  transferase 
D)  dehydratase

Question 10

The enzyme activity catalyzing the reaction shown is best termed a

Accepted Answer

A)  reductase 
B)  ketothiolase 
C)  transferase 
D)  dehydratase 
A)  reductase 
B)  ketothiolase 
C)  transferase 
D)  dehydratase

Question 11

Which of the following are involved in the development of atherosclerosis?

Accepted Answer

A)  Excess LDL 
B)  Inflammation 
C)  Adhesion molecules 
D)  Monocytes 
E)  none of these
F) all of these 
A)  Excess LDL 
B)  Inflammation 
C)  Adhesion molecules 
D)  Monocytes 
E)  none of these
F) all of these

Question 12

Which of the following is not an advantage of fatty acids as a form of energy storage?

Accepted Answer

A)  Fatty acids contain more highly reduced carbons than carbohydrates. 
B)  Their hydrophobic nature allows close packing in adipose tissue. 
C)  Storage of fats in muscle tissue makes it readily available for use during activity. 
D)  Fats contain more energy per gram than sugars. 
E)  They do not require water for storage. 
A)  Fatty acids contain more highly reduced carbons than carbohydrates. 
B)  Their hydrophobic nature allows close packing in adipose tissue. 
C)  Storage of fats in muscle tissue makes it readily available for use during activity. 
D)  Fats contain more energy per gram than sugars. 
E)  They do not require water for storage.

Question 13

The oxidation of unsaturated fatty acids specifically requires

Accepted Answer

A)  a cis-trans isomerase and a reductase. 
B)  a cis-trans isomerase and a dehydrogenase. 
C)  a dehydrogenase and a reductase. 
D)  a dehydrogenase and a hydrase. 
A)  a cis-trans isomerase and a reductase. 
B)  a cis-trans isomerase and a dehydrogenase. 
C)  a dehydrogenase and a reductase. 
D)  a dehydrogenase and a hydrase.

Question 14

Fatty acid catabolism is called b-oxidation,since the second or b carbon from the carboxyl group is the site of oxidation.

Accepted Answer

A) True 
 B)False

Question 15

Carnitine acyltransferase is located in the mitochondrial

Accepted Answer

A)  intermembrane space. 
B)  outer membrane. 
C)  inner membrane. 
D)  matrix. 
A)  intermembrane space. 
B)  outer membrane. 
C)  inner membrane. 
D)  matrix.

Question 16

Which of the following best describes carnitine?

Accepted Answer

A)  It transports fatty acids across the inner mitochondrial membrane for breakdown. 
B)  It transports acetyl-CoA to the cytosol for fatty acid synthesis. 
C)  It's a precursor of cholesterol. 
D)  It carries growing acyl chains during fatty acid synthesis. 
A)  It transports fatty acids across the inner mitochondrial membrane for breakdown. 
B)  It transports acetyl-CoA to the cytosol for fatty acid synthesis. 
C)  It's a precursor of cholesterol. 
D)  It carries growing acyl chains during fatty acid synthesis.

Question 17

The components of lipoproteins such as LDL and HDL which makes them water soluble are

Accepted Answer

A)  proteins. 
B)  phospholipids. 
C)  unesterified cholesterol. 
D)  proteins and phospholipids. 
E)  All of these 
A)  proteins. 
B)  phospholipids. 
C)  unesterified cholesterol. 
D)  proteins and phospholipids. 
E)  All of these

Question 18

When an acyl group is being transferred from the cytosol to the mitochondria for oxidation,the order of the enzymes it encounters is:

Accepted Answer

A)  CPT-I: Carnitine Translocase: CPT-II 
B)  Carnitine Translocase: CPT-I: CPT-II 
C)  CPT-II: Carnitine Translocase: CPT-I 
D)  none of these 
A)  CPT-I: Carnitine Translocase: CPT-II 
B)  Carnitine Translocase: CPT-I: CPT-II 
C)  CPT-II: Carnitine Translocase: CPT-I 
D)  none of these

Question 19

The cyclization reaction that produces lanosterol in the course of steroid biosynthesis is remarkable because

Accepted Answer

A)  it involves large molecules 
B)  it involves methyl groups 
C)  of the extreme conditions under which it takes place 
D)  it is a concerted reaction 
A)  it involves large molecules 
B)  it involves methyl groups 
C)  of the extreme conditions under which it takes place 
D)  it is a concerted reaction

Question 20

When the blood contains a high concentration of LDLs,the cells respond by making fewer receptors to react with the LDL.

Accepted Answer

A) True 
 B)False

Exam 21: Lipid Metabolism

Which of the following is not associated with coronary heart disease?

The yield of ATP from oxidation of an unsaturated fatty acid has what relationship to the yield from the oxidation of a saturated fatty acid with the same number of carbon atoms?

Which of the following vitamins and cofactors is not used in b-oxidation?

Biosynthesis of compound lipids typically takes place

The human lipoproteins with the lowest density are

Phospholipases are designated A,B,etc,based on

The metabolically activated form of a fatty acid is

Which of the following enzyme types is involved in both fatty acid synthesis and breakdown?

The enzyme activity catalyzing the reaction shown is best termed a

The enzyme activity catalyzing the reaction shown is best termed a

Which of the following are involved in the development of atherosclerosis?

Which of the following is not an advantage of fatty acids as a form of energy storage?

The oxidation of unsaturated fatty acids specifically requires

Fatty acid catabolism is called b-oxidation,since the second or b carbon from the carboxyl group is the site of oxidation.

Carnitine acyltransferase is located in the mitochondrial

Which of the following best describes carnitine?

The components of lipoproteins such as LDL and HDL which makes them water soluble are

When an acyl group is being transferred from the cytosol to the mitochondria for oxidation,the order of the enzymes it encounters is:

The cyclization reaction that produces lanosterol in the course of steroid biosynthesis is remarkable because

When the blood contains a high concentration of LDLs,the cells respond by making fewer receptors to react with the LDL.

Biochemistry and the Organization of Cells

Water: The Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of Rna

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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