Question 1

The majority of bacterial DNA is negatively super coiled.

Accepted Answer

A) True 
 B)False

Question 2

How many origins of replication are there in bacteria?

Accepted Answer

A) 0 
B) 1 
C) 2 
D) More than two 
A) 0 
B) 1 
C) 2 
D) More than two

Question 3

An Alu sequence is an example of what?

Accepted Answer

A) Retroelement 
B) Transposable element 
C) Highly repetitive DNA 
D) All of the answers are correct 
A) Retroelement 
B) Transposable element 
C) Highly repetitive DNA 
D) All of the answers are correct

Question 4

About how many bases of DNA wrap around a histone complex?

Accepted Answer

A) 1,000 
A) 1,000

Question 5

The function of condensin is to

Accepted Answer

A)  cause the chromosomes to uncompact following mitosis. 
B)  coat the chromosomes and condense them into heterochromatin through the compaction of radial loops. 
C)  hold the DNA to the histone proteins in the nucleosome core particle. 
D)  trigger DNA to be compacted in a nucleosome core particle. 
E)  none of these 
A)  cause the chromosomes to uncompact following mitosis. 
B)  coat the chromosomes and condense them into heterochromatin through the compaction of radial loops. 
C)  hold the DNA to the histone proteins in the nucleosome core particle. 
D)  trigger DNA to be compacted in a nucleosome core particle. 
E)  none of these

Question 6

Where do kinetochores attach to chromosomes?

Accepted Answer

A) Telomeres 
B) Specific genes on the chromosome 
C) Centromeres 
D) They don't attach to DNA 
A) Telomeres 
B) Specific genes on the chromosome 
C) Centromeres 
D) They don't attach to DNA

Question 7

Which of the following assists the alignment of sister chromatids during metaphase?

Accepted Answer

A) Radial loop domains 
B) Cohesin 
C) Centromeres 
D) Nucleosomes 
E)  Condensin 
A) Radial loop domains 
B) Cohesin 
C) Centromeres 
D) Nucleosomes 
E)  Condensin

Question 8

The majority of the nonrepetitive genes in an organism are found in which of the following?

Accepted Answer

A) Unique sequences 
B) Moderately repetitive sequences 
C) Highly repetitive sequences 
D) None of the answers are correct 
A) Unique sequences 
B) Moderately repetitive sequences 
C) Highly repetitive sequences 
D) None of the answers are correct

Question 9

The 30 nm fiber is formed from arrays of nucleosomes.

Accepted Answer

A) True 
 B)False

Question 10

A Barr body is an example of what?

Accepted Answer

A) Constitutive heterochromatin 
B) Facultative heterochromatin 
C) Constitutive euchromatin 
D) Facultative euchromatin 
A) Constitutive heterochromatin 
B) Facultative heterochromatin 
C) Constitutive euchromatin 
D) Facultative euchromatin

Question 11

Each radial loop domain may contain between 10 and 100 base pairs of DNA.

Accepted Answer

A) True 
 B)False

Question 12

Areas of the chromosome that remain highly condensed are called ______.

Accepted Answer

A) Euchromatin 
B) Facultative heterochromatin 
C) Constitutive heterochromatin 
D) Barr body 
A) Euchromatin 
B) Facultative heterochromatin 
C) Constitutive heterochromatin 
D) Barr body

Question 13

Which of the following would introduce more twists into the DNA molecule of a bacterial cell?

Accepted Answer

A) Negative super coiling 
B) Positive super coiling 
C) Chromatin remodeling 
D) All of the answers are correct 
A) Negative super coiling 
B) Positive super coiling 
C) Chromatin remodeling 
D) All of the answers are correct

Question 14

What is the purpose of MARs and SARs?

Accepted Answer

A)  To bind to the nuclear matrix 
B)  To form loop structure 
C)  To condense DNA 
D)  All of the answers are correct 
A)  To bind to the nuclear matrix 
B)  To form loop structure 
C)  To condense DNA 
D)  All of the answers are correct

Question 15

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Accepted Answer

A) True 
 B)False

Question 16

Unique sequences make up approximately what percent of the human genome?

Accepted Answer

A) 5% 
B) 25% 
C) 40% 
D) 80% 
A) 5% 
B) 25% 
C) 40% 
D) 80%

Question 17

The different DNA configurations that are generated by super coiling are called topoisomers of one another.

Accepted Answer

A) True 
 B)False

Question 18

Chemicals such as quinolones are anti-bacterial. How does it kill bacteria?

Accepted Answer

A) It inhibits DNA gyrase 
B) It inhibits DNA compaction 
C) It inhibits DNA replication 
D) All of the answers are correct 
A) It inhibits DNA gyrase 
B) It inhibits DNA compaction 
C) It inhibits DNA replication 
D) All of the answers are correct

Question 19

A nucleosome is a combination of _______ and _______.

Accepted Answer

A)  histone proteins, scaffold proteins 
B)  RNA, transcription proteins 
C)  DNA, histone proteins 
D)  RNA, histone proteins 
E)  DNA, scaffold proteins 
A)  histone proteins, scaffold proteins 
B)  RNA, transcription proteins 
C)  DNA, histone proteins 
D)  RNA, histone proteins 
E)  DNA, scaffold proteins

Question 20

The DNA of a bacterial cell must be compacted about _______ fold to fit within the confines of the cell.

Accepted Answer

A)  10 
B)  100 
C)  150 
D)  1000 
E)  1,000,000 
A)  10 
B)  100 
C)  150 
D)  1000 
E)  1,000,000

Exam 10: Chromosome Organization and Molecular Structure

The majority of bacterial DNA is negatively super coiled.

How many origins of replication are there in bacteria?

An Alu sequence is an example of what?

About how many bases of DNA wrap around a histone complex?

The function of condensin is to

Where do kinetochores attach to chromosomes?

Which of the following assists the alignment of sister chromatids during metaphase?

The majority of the nonrepetitive genes in an organism are found in which of the following?

The 30 nm fiber is formed from arrays of nucleosomes.

A Barr body is an example of what?

Each radial loop domain may contain between 10 and 100 base pairs of DNA.

Areas of the chromosome that remain highly condensed are called ______.

Which of the following would introduce more twists into the DNA molecule of a bacterial cell?

What is the purpose of MARs and SARs?

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Unique sequences make up approximately what percent of the human genome?

The different DNA configurations that are generated by super coiling are called topoisomers of one another.

Chemicals such as quinolones are anti-bacterial. How does it kill bacteria?

A nucleosome is a combination of _______ and _______.

The DNA of a bacterial cell must be compacted about _______ fold to fit within the confines of the cell.

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular Level

DNA Technologies

Biotechnology

Genomics I: Analysis of DNA

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

Filters

A nucleosome is a combination of _ and _.