Question 1

Insertion sequences can be identified by which of the following?

Accepted Answer

A) Presence of an integrase enzyme 
B) High level of mutation 
C) Presence of inverted repeats at the end of the sequence 
D) Presence of a reverse transcriptase enzyme 
A) Presence of an integrase enzyme 
B) High level of mutation 
C) Presence of inverted repeats at the end of the sequence 
D) Presence of a reverse transcriptase enzyme

Question 2

RAG1 and RAG2 proteins are associated with which of the following?

Accepted Answer

A) Recombination during prophase I of meiosis 
B) Nucleotide excision repair 
C) Transposition 
D) Integration of a bacteriophage into the host genome 
E) Site-specific recombination in antibody genes 
A) Recombination during prophase I of meiosis 
B) Nucleotide excision repair 
C) Transposition 
D) Integration of a bacteriophage into the host genome 
E) Site-specific recombination in antibody genes

Question 3

Transposase is involved with removing the transposable element from its current location.

Accepted Answer

A) True 
 B)False

Question 4

Which of the following is an example of a transposable element in humans?

Accepted Answer

A) Alu 
B) P elements 
C) Mu 
D) Ty 
A) Alu 
B) P elements 
C) Mu 
D) Ty

Question 5

In

Accepted Answer

A) RecG 
B) RecA 
C) RecBCD 
D) RuvABC 
E) coli, a mutation in the genes encoding which of the following proteins would disable the ability of the cell to recognize double-stranded breaks and conduct recombination during meiosis? 
A) RecG 
B) RecA 
C) RecBCD 
D) RuvABC 
E) coli, a mutation in the genes encoding which of the following proteins would disable the ability of the cell to recognize double-stranded breaks and conduct recombination during meiosis?

Question 6

Bacteriophage $\lambda$ inserts into a bacterial chromosome using which of the following?

Accepted Answer

A) Nucleotide excision repair 
B) Endonuclease activity 
C) Site-specific recombination 
D) DNA gap repair 
A) Nucleotide excision repair 
B) Endonuclease activity 
C) Site-specific recombination 
D) DNA gap repair

Question 7

Ty is an example of a retro element in the human genome.

Accepted Answer

A) True 
 B)False

Question 8

The individual who first proposed the existence of transposable elements was ____.

Accepted Answer

A) Sturtevant 
B) Morgan 
C) McClintock 
D) Franklin 
E) Watson 
A) Sturtevant 
B) Morgan 
C) McClintock 
D) Franklin 
E) Watson

Question 9

Which of the following processes accounts for the tremendous variation in antibody structure?

Accepted Answer

A) RNA editing 
B) Site-specific recombination 
C) Integrase activity 
D) Physiological adaptation 
E) Hot spots of mutation in the immunoglobin genes 
A) RNA editing 
B) Site-specific recombination 
C) Integrase activity 
D) Physiological adaptation 
E) Hot spots of mutation in the immunoglobin genes

Question 10

Which of the following is an application of transposon tagging?

Accepted Answer

A) To test if a transposon is replicative 
B) As a tool to clone novel genes 
C) To track the movement of transposons between species 
D) To inactivate transposons in a genome 
A) To test if a transposon is replicative 
B) As a tool to clone novel genes 
C) To track the movement of transposons between species 
D) To inactivate transposons in a genome

Question 11

High numbers of LINEs and SINEs may be due to transposable element activity.

Accepted Answer

A) True 
 B)False

Question 12

The Holliday model is used to explain which of the following?

Accepted Answer

A) Recombination between homologous chromosomes 
B) Recombination between sister chromatids 
C) The migration of transposons 
D) The replication of transposons 
E)  The generation of antibody diversity 
A) Recombination between homologous chromosomes 
B) Recombination between sister chromatids 
C) The migration of transposons 
D) The replication of transposons 
E)  The generation of antibody diversity

Question 13

Which of the following is technically not part of the genetic information of a transposable element?

Accepted Answer

A) Long-terminal repeats 
B) Inverted repeats 
C) Direct repeats 
D) Transposase 
A) Long-terminal repeats 
B) Inverted repeats 
C) Direct repeats 
D) Transposase

Question 14

Which of the following describes attP and attB of bacteriophage $\lambda$?

Accepted Answer

A) Specific proteins in the cell membrane 
B) A unique set of phospholipids that identify the organelle of interest 
C) Glycoproteins in the cell wall 
D) Specific DNA sequences that are recognized by integrase 
A) Specific proteins in the cell membrane 
B) A unique set of phospholipids that identify the organelle of interest 
C) Glycoproteins in the cell wall 
D) Specific DNA sequences that are recognized by integrase

Question 15

Which of the following domain types is unique to the heavy chain of the polypeptide?

Accepted Answer

A) V 
B) D 
C) J 
D) C 
A) V 
B) D 
C) J 
D) C

Exam 19: Recombination and Transposition at the Molecular Level

Insertion sequences can be identified by which of the following?

RAG1 and RAG2 proteins are associated with which of the following?

Transposase is involved with removing the transposable element from its current location.

Which of the following is an example of a transposable element in humans?

In

Bacteriophage λ\lambdaλ inserts into a bacterial chromosome using which of the following?

Ty is an example of a retro element in the human genome.

The individual who first proposed the existence of transposable elements was ____.

Which of the following processes accounts for the tremendous variation in antibody structure?

Which of the following is an application of transposon tagging?

High numbers of LINEs and SINEs may be due to transposable element activity.

The Holliday model is used to explain which of the following?

Which of the following is technically not part of the genetic information of a transposable element?

Which of the following describes attP and attB of bacteriophage λ\lambdaλ ?

Which of the following domain types is unique to the heavy chain of the polypeptide?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

DNA Technologies

Biotechnology

Genomics I: Analysis of DNA

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

Filters

Bacteriophage $\lambda$ inserts into a bacterial chromosome using which of the following?

Which of the following describes attP and attB of bacteriophage $\lambda$ ?