Question 1

To map a gene by chromosome walking, the sequence of the gene to be mapped is required.

Accepted Answer

A) True 
 B)False

Question 2

A _______ is a combination of a plasmid vector and phage $\lambda$.

Accepted Answer

A) contig 
B) artificial chromosome 
C) cosmid 
D) positional clone 
E) transposable element 
A) contig 
B) artificial chromosome 
C) cosmid 
D) positional clone 
E) transposable element

Question 3

The human genome project's first draft took approximately _______ years.

Accepted Answer

A)  5 
B)  13 
C)  20 
D)  50 
E)  2 
A)  5 
B)  13 
C)  20 
D)  50 
E)  2

Question 4

An amplified restriction fragment length polymorphism is a combination of the procedures for producing RFLP and STS markers.

Accepted Answer

A) True 
 B)False

Question 5

Metagenomics refers to the molecular analysis of the entire genome of a species.

Accepted Answer

A) True 
 B)False

Question 6

Comparative genomics attempts to define evolutionary relationships.

Accepted Answer

A) True 
 B)False

Question 7

The human genome consists of approximately _______ base pairs of DNA.

Accepted Answer

A)  100,000 
B)  1 million 
C)  1 billion 
D)  3 billion 
E)  2 trillion 
A)  100,000 
B)  1 million 
C)  1 billion 
D)  3 billion 
E)  2 trillion

Question 8

In positional cloning, which method is used to identify clones that are progressively closer to a gene of interest?

Accepted Answer

A) Chromosome painting 
B) Cytogenetic mapping 
C) Microsatellite analysis 
D) Chromosome walking 
A) Chromosome painting 
B) Cytogenetic mapping 
C) Microsatellite analysis 
D) Chromosome walking

Question 9

The method of sequencing genomic fragments cloned straight from the genome is:

Accepted Answer

A) Cytogenetic mapping 
B) Shotgun sequencing 
C) Southern blotting 
D) Polymerase chain reaction 
A) Cytogenetic mapping 
B) Shotgun sequencing 
C) Southern blotting 
D) Polymerase chain reaction

Question 10

The most common microsatellite in humans is ____.

Accepted Answer

A) (AT)100 
B) (C
A) n 
C) (TG)n 
D) (CAT)n 
A) (AT)100 
B) (C
A) n 
C) (TG)n 
D) (CAT)n

Question 11

Shotgun sequencing is precise enough to achieve a complete genomic sequence without the need for other mapping methods.

Accepted Answer

A) True 
 B)False

Question 12

In shotgun sequencing, how is a complete sequence of a genome reconstructed?

Accepted Answer

A) The entire genome is directly sequenced chromosome by chromosome. 
B) The genome is fragmented and sequences of each fragment are arranged so that overlapping regions are identified. 
C) The sequences of a large number of individuals is obtained and "averaged" to obtain the complete sequence. 
D) The position of each marker and gene are first mapped relative to regions for which the genomic sequence is not known. 
A) The entire genome is directly sequenced chromosome by chromosome. 
B) The genome is fragmented and sequences of each fragment are arranged so that overlapping regions are identified. 
C) The sequences of a large number of individuals is obtained and "averaged" to obtain the complete sequence. 
D) The position of each marker and gene are first mapped relative to regions for which the genomic sequence is not known.

To map a gene by chromosome walking, the sequence of the gene to be mapped is required.

A _______ is a combination of a plasmid vector and phage $\lambda$ .

The human genome project's first draft took approximately _______ years.

An amplified restriction fragment length polymorphism is a combination of the procedures for producing RFLP and STS markers.

Metagenomics refers to the molecular analysis of the entire genome of a species.

Comparative genomics attempts to define evolutionary relationships.

The human genome consists of approximately _______ base pairs of DNA.

In positional cloning, which method is used to identify clones that are progressively closer to a gene of interest?

The method of sequencing genomic fragments cloned straight from the genome is:

The most common microsatellite in humans is ____.

Shotgun sequencing is precise enough to achieve a complete genomic sequence without the need for other mapping methods.

In shotgun sequencing, how is a complete sequence of a genome reconstructed?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular Level

DNA Technologies

Biotechnology

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

Filters

Exam 22: Genomics I: Analysis of DNA

To map a gene by chromosome walking, the sequence of the gene to be mapped is required.

A _______ is a combination of a plasmid vector and phage λ\lambdaλ .

The human genome project's first draft took approximately _______ years.

An amplified restriction fragment length polymorphism is a combination of the procedures for producing RFLP and STS markers.

Metagenomics refers to the molecular analysis of the entire genome of a species.

Comparative genomics attempts to define evolutionary relationships.

The human genome consists of approximately _______ base pairs of DNA.

In positional cloning, which method is used to identify clones that are progressively closer to a gene of interest?

The method of sequencing genomic fragments cloned straight from the genome is:

The most common microsatellite in humans is ____.

Shotgun sequencing is precise enough to achieve a complete genomic sequence without the need for other mapping methods.

In shotgun sequencing, how is a complete sequence of a genome reconstructed?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular Level

DNA Technologies

Biotechnology

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

Filters

A _______ is a combination of a plasmid vector and phage $\lambda$ .