Question 1

A positive Nikolsky sign may be evident in which of the following conditions?

Accepted Answer

A) Pemphigus vulgaris 
B) Cicatricial pemphigoid 
C) Epidermolysis bullosa 
D) All the above 
E) None of the above 
A) Pemphigus vulgaris 
B) Cicatricial pemphigoid 
C) Epidermolysis bullosa 
D) All the above 
E) None of the above

Question 2

Which of the following herpesviruses is most frequently the cause of recurrent oral and perioral vesicular eruptions?

Accepted Answer

A) VZV (varicella-zoster) 
B) EBV (Epstein-Barr) 
C) CMV (cytomegalovirus) 
D) HSV (herpes simplex), type 1 
E) HSV (herpes simplex), type 2 
A) VZV (varicella-zoster) 
B) EBV (Epstein-Barr) 
C) CMV (cytomegalovirus) 
D) HSV (herpes simplex), type 1 
E) HSV (herpes simplex), type 2

Question 3

A positive Nikolsky sign may be seen in which of the following conditions?

Accepted Answer

A) Histoplasmosis 
B) Major aphthae 
C) Minor aphthae 
D) Mucous membrane pemphigoid 
E) None of the above 
A) Histoplasmosis 
B) Major aphthae 
C) Minor aphthae 
D) Mucous membrane pemphigoid 
E) None of the above

Question 4

A patient with a secondary oral herpes simplex infection would:

Accepted Answer

A) Have no circulating antibodies 
B) Experience no pain in association with the disease 
C) Have positive basement membrane immunofluorescence on direct tissue examination 
D) Have fever, malaise, and arthralgia 
E) None of the above 
A) Have no circulating antibodies 
B) Experience no pain in association with the disease 
C) Have positive basement membrane immunofluorescence on direct tissue examination 
D) Have fever, malaise, and arthralgia 
E) None of the above

Question 5

A 55-year-old man presents with a single deep indurated crateriform lesion of the posterior lateral border of the tongue. It is asymptomatic. This could be all of the following except:

Accepted Answer

A) Squamous cell carcinoma 
B) Chronic traumatic ulcer 
C) Secondary herpes 
D) Syphilis 
E) Histoplasmosis 
A) Squamous cell carcinoma 
B) Chronic traumatic ulcer 
C) Secondary herpes 
D) Syphilis 
E) Histoplasmosis

Question 6

A 76-year-old woman presents with multiple painful oral ulcers that have been persistent for at least 3 months. She states that the ulcers are preceded by blisters. She recently developed an ocular irritation that she described as a gritty sensation when she closes her eyes. Other than her chief complaint and hypertension, she is in good health. She most likely has which of the following?

Accepted Answer

A) Primary herpes simplex infection 
B) Epidermolysis bullosa 
C) Erosive lichen planus 
D) Mucous membrane pemphigoid 
E) Tuberculosis 
A) Primary herpes simplex infection 
B) Epidermolysis bullosa 
C) Erosive lichen planus 
D) Mucous membrane pemphigoid 
E) Tuberculosis

Question 7

Direct immunofluorescence staining of a biopsy from a patient with mucous membrane pemphigoid would show immunoglobulin deposition in which of the following microscopic patterns?

Accepted Answer

A) Linear fluorescence of the keratin layer 
B) Linear fluorescence of the basement membrane 
C) Irregular globular fluorescence of the basement membrane 
D) Fluorescence of the submucosal blood vessels 
E) Interepithelial fluorescence 
A) Linear fluorescence of the keratin layer 
B) Linear fluorescence of the basement membrane 
C) Irregular globular fluorescence of the basement membrane 
D) Fluorescence of the submucosal blood vessels 
E) Interepithelial fluorescence

Question 8

A 14-year-old girl presents with several small painful ulcers in her right posterior maxillary buccal attached gingiva. The lesions have been present for 3 days. She has no other oral lesions and is otherwise in good health. This description is suggestive of traumatic ulcers and what other condition?

Accepted Answer

A) Primary herpes simplex infection 
B) Secondary herpes simplex infection 
C) Minor aphthae 
D) Squamous cell carcinoma 
E) Herpangina 
A) Primary herpes simplex infection 
B) Secondary herpes simplex infection 
C) Minor aphthae 
D) Squamous cell carcinoma 
E) Herpangina

Question 9

Which of the following vesiculobullous diseases occurs because of attachment of autoantibodies to antigens (desmoglein 3) in keratinocyte desmosomes?

Accepted Answer

A) Primary herpes simplex infection 
B) Herpes zoster 
C) Pemphigus vulgaris 
D) Mucous membrane pemphigoid 
E) Epidermolysis bullosa 
A) Primary herpes simplex infection 
B) Herpes zoster 
C) Pemphigus vulgaris 
D) Mucous membrane pemphigoid 
E) Epidermolysis bullosa

Question 10

Lesions found in the buccal mucosa, known as Koplik's spots, are first signs of which of the following?

Accepted Answer

A) Erythema multiforme 
B) Herpangina 
C) Rubeola 
D) Varicella 
E) Acute lupus erythematosus 
A) Erythema multiforme 
B) Herpangina 
C) Rubeola 
D) Varicella 
E) Acute lupus erythematosus

Question 11

Herpes simplex infections are most rationally treated with:

Accepted Answer

A) Lysine 
B) Topical clobetasol 
C) Acyclovir 
D) Topically applied tetracycline 
E) Prednisone 
A) Lysine 
B) Topical clobetasol 
C) Acyclovir 
D) Topically applied tetracycline 
E) Prednisone

Question 12

Koplik's spots are tiny buccal mucosal lesions that precede the cutaneous eruption of which of the following diseases?

Accepted Answer

A) Secondary syphilis 
B) Pemphigus vulgaris 
C) Primary herpes simplex labialis 
D) Behçet's syndrome 
E) None of the above 
A) Secondary syphilis 
B) Pemphigus vulgaris 
C) Primary herpes simplex labialis 
D) Behçet's syndrome 
E) None of the above

Question 13

Which of the following vesiculobullous disorders is nonhereditary and occurs almost exclusively on the skin?

Accepted Answer

A) Pemphigus vulgaris 
B) Cicatricial pemphigoid 
C) Epidermolysis bullosa 
D) Lupus erythematosus 
E) Bullous pemphigoid 
A) Pemphigus vulgaris 
B) Cicatricial pemphigoid 
C) Epidermolysis bullosa 
D) Lupus erythematosus 
E) Bullous pemphigoid

Question 14

Herpes simplex virus may cause vesiculoulcerative lesions on any mucosal surface in all the following patients except _____ patients.

Accepted Answer

A) AIDS 
B) Bone marrow transplant 
C) Seropositive 
D) Seronegative 
A) AIDS 
B) Bone marrow transplant 
C) Seropositive 
D) Seronegative

Question 15

Systemic absorption of topical corticosteroids depends on:

Accepted Answer

A) Patient skin pigmentation 
B) Patient ethnicity 
C) Patient gender 
D) All the above 
E) None of the above 
A) Patient skin pigmentation 
B) Patient ethnicity 
C) Patient gender 
D) All the above 
E) None of the above

Question 16

Systemic corticosteroids, when used at relatively high doses and for extended periods, may induce all the following side effects except:

Accepted Answer

A) Elevation of blood pressure 
B) Aggravation of diabetes mellitus 
C) Hyperplasia of the adrenal cortex 
D) Cataracts 
E) Aggravation of tuberculosis 
A) Elevation of blood pressure 
B) Aggravation of diabetes mellitus 
C) Hyperplasia of the adrenal cortex 
D) Cataracts 
E) Aggravation of tuberculosis

Question 17

Epidermolysis bullosa:

Accepted Answer

A) May result in a constricted oral orifice because of scarring 
B) Is a bullous skin disease that may have oral manifestations 
C) May be inherited 
D) May be acquired 
E) All the above 
A) May result in a constricted oral orifice because of scarring 
B) Is a bullous skin disease that may have oral manifestations 
C) May be inherited 
D) May be acquired 
E) All the above

Question 18

Which of the following is important in the clinical efficacy of a topical corticosteroid?

Accepted Answer

A) Vehicle 
B) Concentration of steroid in the preparation 
C) Halogenation of parent compound, cortisol 
D) Frequency and amount of application 
E) All the above 
A) Vehicle 
B) Concentration of steroid in the preparation 
C) Halogenation of parent compound, cortisol 
D) Frequency and amount of application 
E) All the above

Question 19

Cytologic examination can be diagnostic of which of the following diseases?

Accepted Answer

A) Herpes simplex 
B) Recurrent aphthae 
C) Mucous membrane pemphigoid 
D) Erosive lichen planus 
E) Frictional hyperkeratosis 
A) Herpes simplex 
B) Recurrent aphthae 
C) Mucous membrane pemphigoid 
D) Erosive lichen planus 
E) Frictional hyperkeratosis

Question 20

All but one of the following are contagious and thus are potential occupational hazards to the dentist and dental hygienist. Choose the noncontagious condition.

Accepted Answer

A) Oral histoplasmosis 
B) Pemphigus vulgaris 
C) Cold sores 
D) Primary herpes 
E) Oral chancre 
A) Oral histoplasmosis 
B) Pemphigus vulgaris 
C) Cold sores 
D) Primary herpes 
E) Oral chancre

A positive Nikolsky sign may be evident in which of the following conditions?

Which of the following herpesviruses is most frequently the cause of recurrent oral and perioral vesicular eruptions?

A positive Nikolsky sign may be seen in which of the following conditions?

A patient with a secondary oral herpes simplex infection would:

A 55-year-old man presents with a single deep indurated crateriform lesion of the posterior lateral border of the tongue. It is asymptomatic. This could be all of the following except:

Direct immunofluorescence staining of a biopsy from a patient with mucous membrane pemphigoid would show immunoglobulin deposition in which of the following microscopic patterns?

Which of the following vesiculobullous diseases occurs because of attachment of autoantibodies to antigens (desmoglein 3) in keratinocyte desmosomes?

Lesions found in the buccal mucosa, known as Koplik's spots, are first signs of which of the following?

Herpes simplex infections are most rationally treated with:

Koplik's spots are tiny buccal mucosal lesions that precede the cutaneous eruption of which of the following diseases?

Which of the following vesiculobullous disorders is nonhereditary and occurs almost exclusively on the skin?

Herpes simplex virus may cause vesiculoulcerative lesions on any mucosal surface in all the following patients except _____ patients.

Systemic absorption of topical corticosteroids depends on:

Systemic corticosteroids, when used at relatively high doses and for extended periods, may induce all the following side effects except:

Epidermolysis bullosa:

Which of the following is important in the clinical efficacy of a topical corticosteroid?

Cytologic examination can be diagnostic of which of the following diseases?

All but one of the following are contagious and thus are potential occupational hazards to the dentist and dental hygienist. Choose the noncontagious condition.

Ulcerative Conditions

White Lesions

Red-Blue Lesions

Pigmented Lesions

Verrucal-Papillary Lesions

Connective Tissue Lesions

Salivary Gland Diseases

Lymphoid Lesions

Cysts of the Jaws and Neck

Odontogenic Tumors

Benign Nonodontogenic Tumors

Inflammatory Jaw Lesions

Malignancies of the Jaws

Metabolic and Genetic Diseases

Abnormalities of Teeth

Filters

Exam 1: Vesiculobullous Diseases

A positive Nikolsky sign may be evident in which of the following conditions?

Which of the following herpesviruses is most frequently the cause of recurrent oral and perioral vesicular eruptions?

A positive Nikolsky sign may be seen in which of the following conditions?

A patient with a secondary oral herpes simplex infection would:

A 55-year-old man presents with a single deep indurated crateriform lesion of the posterior lateral border of the tongue. It is asymptomatic. This could be all of the following except:

Direct immunofluorescence staining of a biopsy from a patient with mucous membrane pemphigoid would show immunoglobulin deposition in which of the following microscopic patterns?

Which of the following vesiculobullous diseases occurs because of attachment of autoantibodies to antigens (desmoglein 3) in keratinocyte desmosomes?

Lesions found in the buccal mucosa, known as Koplik's spots, are first signs of which of the following?

Herpes simplex infections are most rationally treated with:

Koplik's spots are tiny buccal mucosal lesions that precede the cutaneous eruption of which of the following diseases?

Which of the following vesiculobullous disorders is nonhereditary and occurs almost exclusively on the skin?

Herpes simplex virus may cause vesiculoulcerative lesions on any mucosal surface in all the following patients except _____ patients.

Systemic absorption of topical corticosteroids depends on:

Systemic corticosteroids, when used at relatively high doses and for extended periods, may induce all the following side effects except:

Epidermolysis bullosa:

Which of the following is important in the clinical efficacy of a topical corticosteroid?

Cytologic examination can be diagnostic of which of the following diseases?

All but one of the following are contagious and thus are potential occupational hazards to the dentist and dental hygienist. Choose the noncontagious condition.

Ulcerative Conditions

White Lesions

Red-Blue Lesions

Pigmented Lesions

Verrucal-Papillary Lesions

Connective Tissue Lesions

Salivary Gland Diseases

Lymphoid Lesions

Cysts of the Jaws and Neck

Odontogenic Tumors

Benign Nonodontogenic Tumors

Inflammatory Jaw Lesions

Malignancies of the Jaws

Metabolic and Genetic Diseases

Abnormalities of Teeth

Filters