Exam 15: Drug Addiction and the Brains Reward Circuits

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Chronic use of which drug has been linked to bronchitis, emphysema, cancer, stroke, and heart attack?

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Taking one drug can often produce tolerance to other drugs; such tolerance is called

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The Harrison Narcotics Act, which was passed in the U.S.in 1914, unintentionally encouraged the use of

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These drugs are widely used in the treatment of pain, cough, and diarrhea:

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Many early studies of intracranial self-stimulation focused on the stimulation of the

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Recent research suggests that dopamine release in the nucleus accumbens may be related more to the __________ of reward than to the experience of the reward.

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As drug addiction develops, the control of drug taking seems to spread from the ventral to the dorsal __________.

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Modern physical-dependence theories of drug addiction attempt to account for the fact that addicts frequently relapse after lengthy drug-free periods by postulating

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  -The animal model that best approximates human drug addiction is the -The animal model that best approximates human drug addiction is the

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Some animals will not begin a session of lever pressing for rewarding brain stimulation unless they are given a few free stimulations.This is called

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Describe the physical-dependence and positive-incentive perspectives of addiction.What is the current status of the "debate" between these two perspectives.How well does each account for relapse?.

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Which drug is currently an alternative to methadone as a treatment for heroin addiction?

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Psychoactive drugs are those that affect

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Dr.William Stewart Halsted, a brilliant surgeon and one of the founders of Johns Hopkins Medical School, is considered by many to be the father of modern surgery.Surprisingly, he was addicted to __________ throughout most of his brilliant career.

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The before-and-after design is used to study __________ drug tolerance.

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Drug tolerance is a shift in the dose-response curve

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The lack of strong support for early physical-dependence theories of addiction lent indirect support to the notion that the primary factors in drug addiction are

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Many addicts manage to stop taking the drug to which they are addicted, sometimes for several months, but they usually __________.

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According to Ramsay and Woods, the unconditional stimulus in drug conditioning experiments is

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The branch of the mesotelencephalic dopamine system that projects from the ventral tegmental area is called the

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