Question 1

Which of the following side effects of Lotronex warrants a boxed warning?

Accepted Answer

A) Abdominal pain 
B) Drowsiness 
C) Headache 
D) Ischemic colitis 
A) Abdominal pain 
B) Drowsiness 
C) Headache 
D) Ischemic colitis D

Question 2

Because metoclopramide (Reglan) for nausea and vomiting antagonizes dopamine receptors, it:

Accepted Answer

A) Cannot be used in patients with Parkinson disease 
B) Carries a risk of tardive dyskinesias 
C) Has few side effects 
D) A and B 
A) Cannot be used in patients with Parkinson disease 
B) Carries a risk of tardive dyskinesias 
C) Has few side effects 
D) A and B D

Question 3

Bulk-forming agents are used for:

Accepted Answer

A) Constipation 
B) Nausea 
C) Diarrhea 
D) A and C 
A) Constipation 
B) Nausea 
C) Diarrhea 
D) A and C D

Question 4

The acidity of the stomach is an important consideration in medication administration because:

Accepted Answer

A) Acid deactivates some medications. 
B) Acid-reducing medications may affect the absorption of other medications. 
C) Some medications require an acidic environment for proper absorption. 
D) All of the above are important considerations. 
A) Acid deactivates some medications. 
B) Acid-reducing medications may affect the absorption of other medications. 
C) Some medications require an acidic environment for proper absorption. 
D) All of the above are important considerations.

Question 5

-prazole is the common generic ending for:

Accepted Answer

A) H₂-antagonists 
B) PPIs 
C) 5-aminosalicylates 
D) None of the above 
A) H₂-antagonists 
B) PPIs 
C) 5-aminosalicylates 
D) None of the above

Question 6

Use of which of the following medications can contribute to the development of ulcers?

Accepted Answer

A) NSAIDs 
B) Alcohol 
C) Diuretics 
D) Laxatives 
A) NSAIDs 
B) Alcohol 
C) Diuretics 
D) Laxatives

Question 7

The gallbladder releases:

Accepted Answer

A) Insulin to reduce glucose levels 
B) Bile to aid in the dispersion of fats 
C) Glycogen to increase glucose levels 
D) None of the above 
A) Insulin to reduce glucose levels 
B) Bile to aid in the dispersion of fats 
C) Glycogen to increase glucose levels 
D) None of the above

Question 8

The generic name for Pepcid is:

Accepted Answer

A) Cimetidine 
B) Famotidine 
C) Nizatidine 
D) Ranitidine 
A) Cimetidine 
B) Famotidine 
C) Nizatidine 
D) Ranitidine

Question 9

Bile is produced by the:

Accepted Answer

A) Liver 
B) Pancreas 
C) Small intestine 
D) Appendix 
A) Liver 
B) Pancreas 
C) Small intestine 
D) Appendix

Question 10

The chemoreceptor trigger zone (CTZ) can be activated by:

Accepted Answer

A) Smell, pain, and motion 
B) Emotions 
C) Chemotherapeutic agents 
D) All of the above 
A) Smell, pain, and motion 
B) Emotions 
C) Chemotherapeutic agents 
D) All of the above

Question 11

H. pylori is usually treated with:

Accepted Answer

A) Antibiotics and PPIs 
B) Antibiotics alone 
C) Antacids 
D) PPIs alone 
A) Antibiotics and PPIs 
B) Antibiotics alone 
C) Antacids 
D) PPIs alone

Question 12

Peristalsis occurs in the:

Accepted Answer

A) Esophagus alone 
B) Esophagus and stomach 
C) Stomach and small intestines 
D) Esophagus, stomach, and intestines 
A) Esophagus alone 
B) Esophagus and stomach 
C) Stomach and small intestines 
D) Esophagus, stomach, and intestines

Question 13

Which ingredient helps control flatulence?

Accepted Answer

A) Aluminum hydroxide 
B) Bismuth subsalicylate 
C) Psyllium 
D) Simethicone 
A) Aluminum hydroxide 
B) Bismuth subsalicylate 
C) Psyllium 
D) Simethicone

Question 14

Which of the following is an antidiarrheal medication?

Accepted Answer

A) Cephulac 
B) Lomotil 
C) Antivert 
D) Colace 
A) Cephulac 
B) Lomotil 
C) Antivert 
D) Colace

Question 15

Which of the following medications is a Schedule V (C-V) controlled substance medication?

Accepted Answer

A) ranitidine (Zantac) 
B) pantoprazole (Protonix) 
C) diphenoxylate/atropine (Lomotil) 
D) dicyclomine (Bentyl) 
A) ranitidine (Zantac) 
B) pantoprazole (Protonix) 
C) diphenoxylate/atropine (Lomotil) 
D) dicyclomine (Bentyl)

Question 16

Which type of laxative can lead to physical dependence?

Accepted Answer

A) Stool softeners 
B) Bulk forming 
C) Hyperosmotic 
D) Stimulant 
A) Stool softeners 
B) Bulk forming 
C) Hyperosmotic 
D) Stimulant

Question 17

Adalimumab (Humira) for the treatment of Crohn disease is a(an):

Accepted Answer

A) Tumor necrosis factor-alpha (TNF-a) inhibitor 
B) Alpha-4 integrin antagonist 
C) 5-Aminosalicylate 
D) Antispasmodic medication 
A) Tumor necrosis factor-alpha (TNF-a) inhibitor 
B) Alpha-4 integrin antagonist 
C) 5-Aminosalicylate 
D) Antispasmodic medication

Question 18

Which of the following is considered to be a type of inflammatory bowel disease (IBD)?

Accepted Answer

A) GERD 
B) Ulcerative colitis 
C) Peptic ulcers 
D) Constipation 
A) GERD 
B) Ulcerative colitis 
C) Peptic ulcers 
D) Constipation

Question 19

All of the following are functions of the GI system except:

Accepted Answer

A) Absorption 
B) Digestion 
C) Distribution 
D) Excretion 
A) Absorption 
B) Digestion 
C) Distribution 
D) Excretion

Question 20

Lotronex is only indicated for use in:

Accepted Answer

A) Women 
B) Long-term diarrhea as a result of irritable bowel syndrome (IBS) 
C) Short-term relief of acute diarrhea 
D) A and B 
A) Women 
B) Long-term diarrhea as a result of irritable bowel syndrome (IBS) 
C) Short-term relief of acute diarrhea 
D) A and B

Exam 20: Therapeutic Agents for the Gastrointestinal System

Which of the following side effects of Lotronex warrants a boxed warning?

Because metoclopramide (Reglan) for nausea and vomiting antagonizes dopamine receptors, it:

Bulk-forming agents are used for:

The acidity of the stomach is an important consideration in medication administration because:

-prazole is the common generic ending for:

Use of which of the following medications can contribute to the development of ulcers?

The gallbladder releases:

The generic name for Pepcid is:

Bile is produced by the:

The chemoreceptor trigger zone (CTZ) can be activated by:

H. pylori is usually treated with:

Peristalsis occurs in the:

Which ingredient helps control flatulence?

Which of the following is an antidiarrheal medication?

Which of the following medications is a Schedule V (C-V) controlled substance medication?

Which type of laxative can lead to physical dependence?

Adalimumab (Humira) for the treatment of Crohn disease is a(an):

Which of the following is considered to be a type of inflammatory bowel disease (IBD)?

All of the following are functions of the GI system except:

Lotronex is only indicated for use in:

History of Medicine and Pharmacy

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