Question 1

Complications of amniocentesis include

Accepted Answer

A) Infection 
B) Pyruvate kinase deficiency 
C) Rh sensitization 
D) Thalassemia 
A) Infection 
B) Pyruvate kinase deficiency 
C) Rh sensitization 
D) Thalassemia A

Question 2

Which term refers to delivery of a live infant?

Accepted Answer

A) Gravid 
B) Gravida 
C) Para 
D) Peri 
A) Gravid 
B) Gravida 
C) Para 
D) Peri C

Question 3

Prior to giving Rh-immune globulin (RhIG),when should a second antibody screen be tested on an Rh(D)-negative woman whose initial antibody screen was negative?

Accepted Answer

A) 8 weeks gestation 
B) 12 weeks gestation 
C) 24 weeks gestation 
D) 28 weeks gestation 
A) 8 weeks gestation 
B) 12 weeks gestation 
C) 24 weeks gestation 
D) 28 weeks gestation D

Question 4

How does phototherapy reduce the blood bilirubin level?

Accepted Answer

A) Conjugates bilirubin in the liver to a form that can be excreted in the urine 
B) Conjugates bilirubin in the skin to a form that can be excreted in the bile 
C) Converts unconjugated bilirubin in the skin to a form that can be excreted by the lungs 
D) Converts unconjugated bilirubin in the skin to a form that can be excreted in the urine 
A) Conjugates bilirubin in the liver to a form that can be excreted in the urine 
B) Conjugates bilirubin in the skin to a form that can be excreted in the bile 
C) Converts unconjugated bilirubin in the skin to a form that can be excreted by the lungs 
D) Converts unconjugated bilirubin in the skin to a form that can be excreted in the urine

Question 5

The goal of intrauterine transfusion is increase the fetal hematocrit to

Accepted Answer

A) 25-30% (0.25-0.30) 
B) 32-44% (0.32-0.44) 
C) 40-55% (0.40-0.55) 
D) 45-55% (0.45-0.55) 
A) 25-30% (0.25-0.30) 
B) 32-44% (0.32-0.44) 
C) 40-55% (0.40-0.55) 
D) 45-55% (0.45-0.55)

Question 6

All of the following are pregnancy-related indications for Rh-immune globulin injection except

Accepted Answer

A) Antepartum after abdominal trauma 
B) Perinatal after termination of pregnancy 
C) Postpartum when fetal death occurred 
D) Postpartum when baby is Rh(
D) negative 
A) Antepartum after abdominal trauma 
B) Perinatal after termination of pregnancy 
C) Postpartum when fetal death occurred 
D) Postpartum when baby is Rh(
D) negative

Question 7

Which statement about the direct antiglobulin test (DAT)in the postpartum period is true?

Accepted Answer

A) If the DAT on a cord blood specimen is positive,an eLuᵃte should always be prepared and tested against the biological father's red blood cells. 
B) If the mother has a clinically significant antibody,a DAT should be performed on a blood specimen from the newborn. 
C) Laboratory standards mandate that a DAT be performed on cord blood collected from every live birth. 
D) The strength of the DAT in cases of ABO compatibility is indicative of the severity of the hemolytic process. 
A) If the DAT on a cord blood specimen is positive,an eLuᵃte should always be prepared and tested against the biological father's red blood cells. 
B) If the mother has a clinically significant antibody,a DAT should be performed on a blood specimen from the newborn. 
C) Laboratory standards mandate that a DAT be performed on cord blood collected from every live birth. 
D) The strength of the DAT in cases of ABO compatibility is indicative of the severity of the hemolytic process.

Question 8

A minimum of at least one ______ dose of Rh-immune globulin (RhIG)must be administered to all Rh(D)-negative women who deliver an Rh(D)-positive infant,provided the woman has not already made anti-D.

Accepted Answer

A) 100 µg 
B) 200 µg 
C) 300 µg 
D) 400 µg 
A) 100 µg 
B) 200 µg 
C) 300 µg 
D) 400 µg

Question 9

All of the following are known to be IgM antibodies and have not been found to cause hemolytic disease of the fetus and newborn (HDFN)except

Accepted Answer

A) Anti-Leᵃ 
B) Anti-Leᵇ 
C) Anti-M 
D) Anti-P1 
A) Anti-Leᵃ 
B) Anti-Leᵇ 
C) Anti-M 
D) Anti-P1

Question 10

The most common cause of hemolytic disease of the newborn is incompatibility between the mother and the infant in which blood group system?

Accepted Answer

A) ABO 
B) Kell 
C) MNS 
D) Rh 
A) ABO 
B) Kell 
C) MNS 
D) Rh

Question 11

Infants at risk for severe cytomegalovirus (CMV)infection include all of the following except

Accepted Answer

A) Infants born prematurely 
B) Infants born to CMV-seropositive mothers 
C) Infants with low birth weight who are undergoing ECMO 
D) Infants with congenital immunodeficiency disorders 
A) Infants born prematurely 
B) Infants born to CMV-seropositive mothers 
C) Infants with low birth weight who are undergoing ECMO 
D) Infants with congenital immunodeficiency disorders

Question 12

The model or classic case of hemolytic disease of the fetus and newborn (HDFN)involves an

Accepted Answer

A) Rh(
D) -negative mother who makes anti-A directed against the Rh(
D) -negative red blood cells of her fetus 
B) Rh(
D) -negative mother who makes anti-D directed against the Rh(
D) -positive red blood cells of her fetus 
C) Rh(
D) -positive mother who makes anti-A,B directed against the Rh(
D) -negative red blood cells of her fetus 
D) Rh(
D) -positive mother who makes anti-D directed against the Rh(
D) -negative red blood cells of her fetus 
A) Rh(
D) -negative mother who makes anti-A directed against the Rh(
D) -negative red blood cells of her fetus 
B) Rh(
D) -negative mother who makes anti-D directed against the Rh(
D) -positive red blood cells of her fetus 
C) Rh(
D) -positive mother who makes anti-A,B directed against the Rh(
D) -negative red blood cells of her fetus 
D) Rh(
D) -positive mother who makes anti-D directed against the Rh(
D) -negative red blood cells of her fetus

Question 13

Amniocentesis can be performed as early as

Accepted Answer

A) 10 weeks gestation 
B) 15 weeks gestation 
C) 20 weeks gestation 
D) 25 weeks gestation 
A) 10 weeks gestation 
B) 15 weeks gestation 
C) 20 weeks gestation 
D) 25 weeks gestation

Question 14

An exchange transfusion will accomplish all of the following except

Accepted Answer

A) Reduce the amount of antibody-coated red blood cells in the newborn's circulation 
B) Reduce the amount of maternal antibody in the newborn's circulation 
C) Reduce the bilirubin level in the newborn's circulation 
D) Reduce the hemoglobin level in the newborn's circulation 
A) Reduce the amount of antibody-coated red blood cells in the newborn's circulation 
B) Reduce the amount of maternal antibody in the newborn's circulation 
C) Reduce the bilirubin level in the newborn's circulation 
D) Reduce the hemoglobin level in the newborn's circulation

Question 15

Which method is the most accurate means of determining the severity of fetal hemolytic anemia and the need for treatment of the fetus?

Accepted Answer

A) Amniotic fluid analysis 
B) Doppler flow studies 
C) Fetal blood sampling 
D) Maternal antibody titer 
A) Amniotic fluid analysis 
B) Doppler flow studies 
C) Fetal blood sampling 
D) Maternal antibody titer

Question 16

How can pregnancy cause a woman to make an antibody to a red blood cell antigen?

Accepted Answer

A) Fetal cells carrying an antigen inherited from the mother and foreign to the father cross the placenta 
B) Fetal cells carrying an antigen inherited from the father and foreign to the mother cross the placenta 
C) Fetal cells carrying a homozygous dose of an antigen cross the placenta 
D) Fetal cells carrying a heterozygous dose of an antigen cross the placenta 
A) Fetal cells carrying an antigen inherited from the mother and foreign to the father cross the placenta 
B) Fetal cells carrying an antigen inherited from the father and foreign to the mother cross the placenta 
C) Fetal cells carrying a homozygous dose of an antigen cross the placenta 
D) Fetal cells carrying a heterozygous dose of an antigen cross the placenta

Question 17

Which donor red blood cells would be chosen to use in an intrauterine transfusion?

Accepted Answer

A) Group AB,Rh(
D) negative that lack the offending antigen 
B) Group AB,Rh(
E) negative that lack the offending antigen 
C) Group O,Rh(
C) negative that lack the offending antigen 
D) Group O,Rh(
D) negative that lack the offending antigen 
A) Group AB,Rh(
D) negative that lack the offending antigen 
B) Group AB,Rh(
E) negative that lack the offending antigen 
C) Group O,Rh(
C) negative that lack the offending antigen 
D) Group O,Rh(
D) negative that lack the offending antigen

Question 18

The normal range for hemoglobin level in a healthy,full-term newborn is approximately

Accepted Answer

A) 10.0-12.0 g/dL (100-120 g/L) 
B) 14.0-20.0 g/dL (140-200 g/L) 
C) 20.0-25.0 g/dL (200-250 g/L) 
D) 23.0-32.0 g/dL (230-320 g/L) 
A) 10.0-12.0 g/dL (100-120 g/L) 
B) 14.0-20.0 g/dL (140-200 g/L) 
C) 20.0-25.0 g/dL (200-250 g/L) 
D) 23.0-32.0 g/dL (230-320 g/L)

Question 19

Which of the following is the condition where bilirubin crosses the blood-brain barrier and is deposited in the cells of the basal ganglia and hippocampus?

Accepted Answer

A) Anemia 
B) Hepatosplenomegaly 
C) Jaundice 
D) Kernicterus 
A) Anemia 
B) Hepatosplenomegaly 
C) Jaundice 
D) Kernicterus

Question 20

In general,for the neonatal population,a platelet count of ___________ is considered the minimum to maintain hemostasis.

Accepted Answer

A) 50 × 10³/µL (50 × 10⁹/L) 
B) 75 × 10³/µL (75 × 10⁹/L) 
C) 100 × 10³/µL (100 × 10⁹/L) 
D) 150 × 10³/µL (150 × 10⁹/L) 
A) 50 × 10³/µL (50 × 10⁹/L) 
B) 75 × 10³/µL (75 × 10⁹/L) 
C) 100 × 10³/µL (100 × 10⁹/L) 
D) 150 × 10³/µL (150 × 10⁹/L)

Exam 14: Perinatal and Neonatal Transfusion Issues

Complications of amniocentesis include

Which term refers to delivery of a live infant?

Prior to giving Rh-immune globulin (RhIG),when should a second antibody screen be tested on an Rh(D)-negative woman whose initial antibody screen was negative?

How does phototherapy reduce the blood bilirubin level?

The goal of intrauterine transfusion is increase the fetal hematocrit to

All of the following are pregnancy-related indications for Rh-immune globulin injection except

Which statement about the direct antiglobulin test (DAT)in the postpartum period is true?

A minimum of at least one ______ dose of Rh-immune globulin (RhIG)must be administered to all Rh(D)-negative women who deliver an Rh(D)-positive infant,provided the woman has not already made anti-D.

All of the following are known to be IgM antibodies and have not been found to cause hemolytic disease of the fetus and newborn (HDFN)except

The most common cause of hemolytic disease of the newborn is incompatibility between the mother and the infant in which blood group system?

Infants at risk for severe cytomegalovirus (CMV)infection include all of the following except

The model or classic case of hemolytic disease of the fetus and newborn (HDFN)involves an

Amniocentesis can be performed as early as

An exchange transfusion will accomplish all of the following except

Which method is the most accurate means of determining the severity of fetal hemolytic anemia and the need for treatment of the fetus?

How can pregnancy cause a woman to make an antibody to a red blood cell antigen?

Which donor red blood cells would be chosen to use in an intrauterine transfusion?

The normal range for hemoglobin level in a healthy,full-term newborn is approximately

Which of the following is the condition where bilirubin crosses the blood-brain barrier and is deposited in the cells of the basal ganglia and hippocampus?

In general,for the neonatal population,a platelet count of ___________ is considered the minimum to maintain hemostasis.

The Immune Process: the Origin and Interaction Between Antigens and Antibodies

Immunogenetics: the Origin of Antigens

Blood Bank Applications of Antigenantibody Reactions

Abo and Hh Blood Group Systems

Rh, Rhag, and Lw Blood Group Systems

Other Blood Group Systems

Pretransfusion and Compatibility Testing

Identification of Unexpected Antibodies

Donor Selection, Phlebotomy, and Required Testing

Blood Products: Preparation, Storage, and Shipment of Blood Components

Component Therapy and Massive Transfusion

Adverse Reactions to Transfusion

Transfusion-Transmitted Infections

Autoimmune and Drug-Induced Immune Hemolytic Anemias

Platelet Refractory Patients

Transfusion Support of Selected Patient Populations

Human Histocompatibility

Methods in Parentage Testing

Transfusion Safety and Regulatory Issues

Quality Assurance

Filters