Question 1

The McLeod phenotype is very rare and is often associated with a hereditary form of

Accepted Answer

A) Chronic granulomatous disease (CG
D)  
B) Cold agglutinin syndrome (CAS) 
C) Paroxysmal cold hemoglobinuria (PCH) 
D) Paroxysmal nocturnal hemoglobinemia (PNH) 
A) Chronic granulomatous disease (CG
D)  
B) Cold agglutinin syndrome (CAS) 
C) Paroxysmal cold hemoglobinuria (PCH) 
D) Paroxysmal nocturnal hemoglobinemia (PNH) A

Question 2

Antibodies in the Ii blood group system are usually

Accepted Answer

A) IgG alloantibodies that are detected when testing occurs at body temperature 
B) IgG autoantibodies that are detected when testing occurs at room temperature 
C) IgM alloantibodies that are detected when testing occurs at body temperature 
D) IgM autoantibodies that are detected when testing occurs at room temperature 
A) IgG alloantibodies that are detected when testing occurs at body temperature 
B) IgG autoantibodies that are detected when testing occurs at room temperature 
C) IgM alloantibodies that are detected when testing occurs at body temperature 
D) IgM autoantibodies that are detected when testing occurs at room temperature D

Question 3

All GPI-linked glycoproteins are absent in individuals suffering from which condition?

Accepted Answer

A) Chronic granulomatous disease (CG
D)  
B) Hemolytic disease of the fetus and newborn (HDFN) 
C) Paroxysmal cold hemoglobinuria (PCH) 
D) Paroxysmal nocturnal hemoglobinemia (PNH) 
A) Chronic granulomatous disease (CG
D)  
B) Hemolytic disease of the fetus and newborn (HDFN) 
C) Paroxysmal cold hemoglobinuria (PCH) 
D) Paroxysmal nocturnal hemoglobinemia (PNH) D

Question 4

Detection of anti-i has been associated with

Accepted Answer

A) hemolytic disease of the fetus and newborn 
B) infectious mononucleosis 
C) paroxysmal cold hemoglobinuria 
D) sickle cell anemia 
A) hemolytic disease of the fetus and newborn 
B) infectious mononucleosis 
C) paroxysmal cold hemoglobinuria 
D) sickle cell anemia

Question 5

Within the Knops blood group system,all of the following are high-incidence antigens except

Accepted Answer

A) Kna 
B) McCa 
C) McCb 
D) Yka 
A) Kna 
B) McCa 
C) McCb 
D) Yka

Question 6

The most common chemical reagent used in North America to alter reagent red blood cells is the enzyme

Accepted Answer

A) bromelin 
B) ficin 
C) papain 
D) trypsin 
A) bromelin 
B) ficin 
C) papain 
D) trypsin

Question 7

Which antigen is one of the antigens in the ISBT classification called Series 901?

Accepted Answer

A) Bga 
B) Knb 
C) Sda 
D) Tcc 
A) Bga 
B) Knb 
C) Sda 
D) Tcc

Question 8

A gene,XK,carried on the X chromosome results in production of the high-incidence antigen

Accepted Answer

A) Jsb 
B) KEL 
C) Kpb 
D) Kx 
A) Jsb 
B) KEL 
C) Kpb 
D) Kx

Question 9

Which antibody commonly causes delayed hemolytic transfusion reactions?

Accepted Answer

A) Anti-A,B 
B) Anti-Jkᵃ 
C) Anti-K 
D) Anti-Leᵃ 
A) Anti-A,B 
B) Anti-Jkᵃ 
C) Anti-K 
D) Anti-Leᵃ

Question 10

How many antigens are there in the Duffy blood group system?

Accepted Answer

A) 3 
B) 6 
C) 8 
D) 9 
A) 3 
B) 6 
C) 8 
D) 9

Question 11

The full expression of Lewis antigens is not reached until around ___ years of age.

Accepted Answer

A) 3 
B) 5 
C) 7 
D) 9 
A) 3 
B) 5 
C) 7 
D) 9

Question 12

The Xgᵃ antigen results from a gene on the ____ chromosome.

Accepted Answer

A) X 
B) Y 
C) XG 
D) YG 
A) X 
B) Y 
C) XG 
D) YG

Question 13

Regarding antigens in the Duffy system,all of the following statements are true except

Accepted Answer

A) Commonly encountered antigens include the allelic pair Fyᵃ and Fyᵇ. 
B) Duffy antigens are well developed at birth. 
C) Fy3 and Fy5 antigens are destroyed by treatment with ficin enzyme. 
D) Fyx is a weak expression of the Fyᵇ antigen. 
A) Commonly encountered antigens include the allelic pair Fyᵃ and Fyᵇ. 
B) Duffy antigens are well developed at birth. 
C) Fy3 and Fy5 antigens are destroyed by treatment with ficin enzyme. 
D) Fyx is a weak expression of the Fyᵇ antigen.

Question 14

Which antigens in the Lutheran system are not high-incidence antigens?

Accepted Answer

A) Auᵃ,Auᵇ,and Luᵃ 
B) Auᵃ,Auᵇ,and Luᵇ 
C) Luᵃ,Luᵇ,and AnWj 
D) Luᵃ,Luᵇ,and Lu3 
A) Auᵃ,Auᵇ,and Luᵃ 
B) Auᵃ,Auᵇ,and Luᵇ 
C) Luᵃ,Luᵇ,and AnWj 
D) Luᵃ,Luᵇ,and Lu3

Question 15

The antigens of the Kell system are found on a ________ that passes through the red blood cell membrane.

Accepted Answer

A) glycogen 
B) glycolipid 
C) glycophorin 
D) glycoprotein 
A) glycogen 
B) glycolipid 
C) glycophorin 
D) glycoprotein

Question 16

How many antigens are in the Cartwright blood group system?

Accepted Answer

A) 2 
B) 3 
C) 4 
D) 5 
A) 2 
B) 3 
C) 4 
D) 5

Question 17

The antigens of the Chido/Rodgers system are located on the _____ complement component.

Accepted Answer

A) C1 
B) C2 
C) C3 
D) C4 
A) C1 
B) C2 
C) C3 
D) C4

Question 18

How many antigens are in the Kidd system?

Accepted Answer

A) 3 
B) 9 
C) 12 
D) 19 
A) 3 
B) 9 
C) 12 
D) 19

Question 19

The null phenotype in the Duffy system is produced by inheriting

Accepted Answer

A) the genotype Fyᵃ/Fyᵃ 
B) the phenotype Fy (a+b-) 
C) the FY3 antigen 
D) two FY genes 
A) the genotype Fyᵃ/Fyᵃ 
B) the phenotype Fy (a+b-) 
C) the FY3 antigen 
D) two FY genes

Question 20

Which of the following blood group systems has unknown clinical significance?

Accepted Answer

A) Yt 
B) Scianna 
C) Gill 
D) Raph 
A) Yt 
B) Scianna 
C) Gill 
D) Raph

Exam 6: Other Blood Group Systems

The McLeod phenotype is very rare and is often associated with a hereditary form of

Antibodies in the Ii blood group system are usually

All GPI-linked glycoproteins are absent in individuals suffering from which condition?

Detection of anti-i has been associated with

Within the Knops blood group system,all of the following are high-incidence antigens except

The most common chemical reagent used in North America to alter reagent red blood cells is the enzyme

Which antigen is one of the antigens in the ISBT classification called Series 901?

A gene,XK,carried on the X chromosome results in production of the high-incidence antigen

Which antibody commonly causes delayed hemolytic transfusion reactions?

How many antigens are there in the Duffy blood group system?

The full expression of Lewis antigens is not reached until around ___ years of age.

The Xgᵃ antigen results from a gene on the ____ chromosome.

Regarding antigens in the Duffy system,all of the following statements are true except

Which antigens in the Lutheran system are not high-incidence antigens?

The antigens of the Kell system are found on a ________ that passes through the red blood cell membrane.

How many antigens are in the Cartwright blood group system?

The antigens of the Chido/Rodgers system are located on the _____ complement component.

How many antigens are in the Kidd system?

The null phenotype in the Duffy system is produced by inheriting

Which of the following blood group systems has unknown clinical significance?

The Immune Process: the Origin and Interaction Between Antigens and Antibodies

Immunogenetics: the Origin of Antigens

Blood Bank Applications of Antigenantibody Reactions

Abo and Hh Blood Group Systems

Rh, Rhag, and Lw Blood Group Systems

Pretransfusion and Compatibility Testing

Identification of Unexpected Antibodies

Donor Selection, Phlebotomy, and Required Testing

Blood Products: Preparation, Storage, and Shipment of Blood Components

Component Therapy and Massive Transfusion

Adverse Reactions to Transfusion

Transfusion-Transmitted Infections

Perinatal and Neonatal Transfusion Issues

Autoimmune and Drug-Induced Immune Hemolytic Anemias

Platelet Refractory Patients

Transfusion Support of Selected Patient Populations

Human Histocompatibility

Methods in Parentage Testing

Transfusion Safety and Regulatory Issues

Quality Assurance

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