Question 1

Most ABO antibodies are

Accepted Answer

A) IgA 
B) IgE 
C) IgG 
D) IgM 
A) IgA 
B) IgE 
C) IgG 
D) IgM D

Question 2

How many nucleotide differences are there between the A and B genes?

Accepted Answer

A) 3 
B) 4 
C) 6 
D) 7 
A) 3 
B) 4 
C) 6 
D) 7 D

Question 3

If an ABO discrepancy is due to an antibody and a low-incidence antigen is suspected,a viable course of action would be to test several different examples of

Accepted Answer

A) A or B cells 
B) A or O cells 
C) B or O cells 
D) AB cells 
A) A or B cells 
B) A or O cells 
C) B or O cells 
D) AB cells A

Question 4

ABO discrepancies are categorized into ____ groups.

Accepted Answer

A) two 
B) three 
C) four 
D) five 
A) two 
B) three 
C) four 
D) five

Question 5

Which gene is an amorph,meaning no functional gene product is produced from this sequence of DNA?

Accepted Answer

A) A 
B) B 
C) H 
D) O 
A) A 
B) B 
C) H 
D) O

Question 6

Antibodies that develop without any apparent stimulus are called

Accepted Answer

A) Actively occurring 
B) Innately occurring 
C) Naturally occurring 
D) Passively occurring 
A) Actively occurring 
B) Innately occurring 
C) Naturally occurring 
D) Passively occurring

Question 7

The red blood cells of the Bombay phenotype appear to be group ____ in routine ABO testing.

Accepted Answer

A) A 
B) B 
C) AB 
D) O 
A) A 
B) B 
C) AB 
D) O

Question 8

In order to avoid the chance of an acute hemolytic transfusion reaction,most laboratories will transfuse only group ____ red blood cell units and group ____ plasma products to patients who have an unresolved ABO-typing discrepancy.

Accepted Answer

A) A,AB 
B) B,AB 
C) O,AB 
D) A,B 
A) A,AB 
B) B,AB 
C) O,AB 
D) A,B

Question 9

All of the following are true of the cis-AB genotype except

Accepted Answer

A) May be easily distinguished in routine laboratory testing 
B) May occur in a child if a crossover event happened to one of the parent's chromosomes 
C) May result from a mutation that produces an unusual enzyme 
D) May result from both the A and B genes residing on one chromosome 
A) May be easily distinguished in routine laboratory testing 
B) May occur in a child if a crossover event happened to one of the parent's chromosomes 
C) May result from a mutation that produces an unusual enzyme 
D) May result from both the A and B genes residing on one chromosome

Question 10

Which of the following individuals first described the ABO blood group system?

Accepted Answer

A) Decastello 
B) Landsteiner 
C) Sturli 
D) Yamamoto 
A) Decastello 
B) Landsteiner 
C) Sturli 
D) Yamamoto

Question 11

Alloantibodies that cause problems in ABO typing include

Accepted Answer

A) anti-Jkᵃ 
B) anti-P1 
C) A₁ lectin 
D) A₂ lectin 
A) anti-Jkᵃ 
B) anti-P1 
C) A₁ lectin 
D) A₂ lectin

Question 12

Possible causes of a missing or weak reaction in the forward group include all of the following except

Accepted Answer

A) Disease that alters the ABO antigen expression 
B) Excessive soLuᵇle ABO antigens in patient/donor's plasma 
C) Hypogammaglobulinemia 
D) Transfusion or transplantation 
A) Disease that alters the ABO antigen expression 
B) Excessive soLuᵇle ABO antigens in patient/donor's plasma 
C) Hypogammaglobulinemia 
D) Transfusion or transplantation

Question 13

Which gene produces an enzyme that attaches an immunodominant sugar to type 1 precursor substance to form the H antigen?

Accepted Answer

A) h 
B) H 
C) se 
D) Se 
A) h 
B) H 
C) se 
D) Se

Question 14

Cold-reactive alloantibodies can be identified by testing plasma against panels of cells with known

Accepted Answer

A) antibodies 
B) genes 
C) microorganisms 
D) phenotypes 
A) antibodies 
B) genes 
C) microorganisms 
D) phenotypes

Question 15

Mixed field reaction is commonly seen in the forward ABO test if a group _________ patient has received an emergency transfusion of group ____ cells.

Accepted Answer

A) A,A 
B) A,B 
C) A,O 
D) O,O 
A) A,A 
B) A,B 
C) A,O 
D) O,O

Question 16

To confirm anti-A₁ in a person who has not been recently transfused,type the patient/donor cells with

Accepted Answer

A) anti-A₁ lectin 
B) anti-A₂ lectin 
C) anti-B lectin 
D) anti-O lectin 
A) anti-A₁ lectin 
B) anti-A₂ lectin 
C) anti-B lectin 
D) anti-O lectin

Question 17

The gene for the ABO blood group system resides on chromosome

Accepted Answer

A) 3 
B) 5 
C) 9 
D) 11 
A) 3 
B) 5 
C) 9 
D) 11

Question 18

The most common ABO blood group is group

Accepted Answer

A) A 
B) B 
C) AB 
D) O 
A) A 
B) B 
C) AB 
D) O

Question 19

What is the immunodominant sugar of the A antigen?

Accepted Answer

A) D-galactose 
B) D-glucose 
C) N-acetyl-D-galactosamine 
D) L-fucose 
A) D-galactose 
B) D-glucose 
C) N-acetyl-D-galactosamine 
D) L-fucose

Question 20

Forward grouping

Accepted Answer

A) Identifies antibody by combining the unknown plasma with known ABO red blood cells 
B) Identifies antigen by combining the unknown red blood cells with known antibody 
C) Occurs when the results of the forward and reverse grouping do not correlate 
D) Occurs when the results for the A and B antigen do not correlate 
A) Identifies antibody by combining the unknown plasma with known ABO red blood cells 
B) Identifies antigen by combining the unknown red blood cells with known antibody 
C) Occurs when the results of the forward and reverse grouping do not correlate 
D) Occurs when the results for the A and B antigen do not correlate

Exam 4: Abo and Hh Blood Group Systems

Most ABO antibodies are

How many nucleotide differences are there between the A and B genes?

If an ABO discrepancy is due to an antibody and a low-incidence antigen is suspected,a viable course of action would be to test several different examples of

ABO discrepancies are categorized into ____ groups.

Which gene is an amorph,meaning no functional gene product is produced from this sequence of DNA?

Antibodies that develop without any apparent stimulus are called

The red blood cells of the Bombay phenotype appear to be group ____ in routine ABO testing.

In order to avoid the chance of an acute hemolytic transfusion reaction,most laboratories will transfuse only group ____ red blood cell units and group ____ plasma products to patients who have an unresolved ABO-typing discrepancy.

All of the following are true of the cis-AB genotype except

Which of the following individuals first described the ABO blood group system?

Alloantibodies that cause problems in ABO typing include

Possible causes of a missing or weak reaction in the forward group include all of the following except

Which gene produces an enzyme that attaches an immunodominant sugar to type 1 precursor substance to form the H antigen?

Cold-reactive alloantibodies can be identified by testing plasma against panels of cells with known

Mixed field reaction is commonly seen in the forward ABO test if a group _________ patient has received an emergency transfusion of group ____ cells.

To confirm anti-A₁ in a person who has not been recently transfused,type the patient/donor cells with

The gene for the ABO blood group system resides on chromosome

The most common ABO blood group is group

What is the immunodominant sugar of the A antigen?

Forward grouping

The Immune Process: the Origin and Interaction Between Antigens and Antibodies

Immunogenetics: the Origin of Antigens

Blood Bank Applications of Antigenantibody Reactions

Rh, Rhag, and Lw Blood Group Systems

Other Blood Group Systems

Pretransfusion and Compatibility Testing

Identification of Unexpected Antibodies

Donor Selection, Phlebotomy, and Required Testing

Blood Products: Preparation, Storage, and Shipment of Blood Components

Component Therapy and Massive Transfusion

Adverse Reactions to Transfusion

Transfusion-Transmitted Infections

Perinatal and Neonatal Transfusion Issues

Autoimmune and Drug-Induced Immune Hemolytic Anemias

Platelet Refractory Patients

Transfusion Support of Selected Patient Populations

Human Histocompatibility

Methods in Parentage Testing

Transfusion Safety and Regulatory Issues

Quality Assurance

Filters

In order to avoid the chance of an acute hemolytic transfusion reaction,most laboratories will transfuse only group red blood cell units and group plasma products to patients who have an unresolved ABO-typing discrepancy.

Mixed field reaction is commonly seen in the forward ABO test if a group _____ patient has received an emergency transfusion of group cells.