Question 1

Which statement most accurately describes prescription drug abuse?

Accepted Answer

A)  a growing problem associated with significant morbidity and mortality 
B)  incidence has decreased over the past two decades 
C)  rarely leads to emergency department visits or accidental overdose 
D)  the leading cause of accidental death in the United States 
E)  primarily due to overprescribing by physicians and nurse practitioners 
A)  a growing problem associated with significant morbidity and mortality 
B)  incidence has decreased over the past two decades 
C)  rarely leads to emergency department visits or accidental overdose 
D)  the leading cause of accidental death in the United States 
E)  primarily due to overprescribing by physicians and nurse practitioners A

Question 2

The neuronal effects of Δ⁹-tetrahydrocannabinol are believed to result from activation of receptors that are coupled with which cellular effect?

Accepted Answer

A)  sodium channel activation 
B)  calcium channel activation 
C)  inhibition of adenylyl cyclase 
D)  inhibition of guanylyl cyclase 
E)  synthesis of inositol triphosphate 
A)  sodium channel activation 
B)  calcium channel activation 
C)  inhibition of adenylyl cyclase 
D)  inhibition of guanylyl cyclase 
E)  synthesis of inositol triphosphate C

Question 3

Which mechanism is responsible for the efficacy of fomepizole in treating ethylene glycol poisoning?

Accepted Answer

A)  inactivation 
B)  inhibition of toxic metabolite formation 
C)  enhanced excretion 
D)  accelerated degradation to inactive compounds 
E)  competitive antagonism of ethylene glycol 
A)  inactivation 
B)  inhibition of toxic metabolite formation 
C)  enhanced excretion 
D)  accelerated degradation to inactive compounds 
E)  competitive antagonism of ethylene glycol B

Question 4

The reinforcement of drug use is partly determined by the peak rate of release of which neurotransmitter in the nucleus accumbens?

Accepted Answer

A)  serotonin 
B)  norepinephrine 
C)  dopamine 
D)  glutamate 
E)  acetylcholine 
A)  serotonin 
B)  norepinephrine 
C)  dopamine 
D)  glutamate 
E)  acetylcholine

Exam 25: Drugs of Abuse

Which statement most accurately describes prescription drug abuse?

The neuronal effects of Δ⁹-tetrahydrocannabinol are believed to result from activation of receptors that are coupled with which cellular effect?

Which mechanism is responsible for the efficacy of fomepizole in treating ethylene glycol poisoning?

The reinforcement of drug use is partly determined by the peak rate of release of which neurotransmitter in the nucleus accumbens?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiviral Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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