Question 1

Dietary modifications that lower the ratio of LDL-cholesterol to HDL-cholesterol include an increased intake of which nutrient?

Accepted Answer

A)  trans isomers of fatty acids 
B)  saturated fat 
C)  polyunsaturated fat 
D)  omega-3 (n-3) fatty acids 
E)  partially hydrogenated plant oils 
A)  trans isomers of fatty acids 
B)  saturated fat 
C)  polyunsaturated fat 
D)  omega-3 (n-3) fatty acids 
E)  partially hydrogenated plant oils D

Question 2

In addition to their beneficial effect on serum LDL-cholesterol levels, atorvastatin and related drugs may reduce coronary heart disease by which mechanism?

Accepted Answer

A)  reducing cholesterol absorption 
B)  improving vascular endothelial function 
C)  stimulating lipoprotein lipase 
D)  increasing lipolysis 
E)  decreasing appetite 
A)  reducing cholesterol absorption 
B)  improving vascular endothelial function 
C)  stimulating lipoprotein lipase 
D)  increasing lipolysis 
E)  decreasing appetite B

Question 3

At what level of serum LDL-cholesterol do persons with symptomatic coronary artery disease benefit from drug therapy to lower these levels?

Accepted Answer

A)  >175 mg/dL 
B)  >150 mg/dL 
C)  >100 mg/dL 
D)  >70 mg/dL 
E)  They benefit regardless of level. 
A)  >175 mg/dL 
B)  >150 mg/dL 
C)  >100 mg/dL 
D)  >70 mg/dL 
E)  They benefit regardless of level. E

Question 4

A man taking simvastatin develops severe muscle pain, muscle inflammation,
And dark urine after beginning concurrent therapy with another drug.Which agent is most likely responsible for this adverse drug interaction?

Accepted Answer

A)  ezetimibe 
B)  cholestyramine 
C)  itraconazole 
D)  rifampin 
E)  penicillin 
A)  ezetimibe 
B)  cholestyramine 
C)  itraconazole 
D)  rifampin 
E)  penicillin

Exam 15: Drugs for Hyperlipidemia

Dietary modifications that lower the ratio of LDL-cholesterol to HDL-cholesterol include an increased intake of which nutrient?

In addition to their beneficial effect on serum LDL-cholesterol levels, atorvastatin and related drugs may reduce coronary heart disease by which mechanism?

At what level of serum LDL-cholesterol do persons with symptomatic coronary artery disease benefit from drug therapy to lower these levels?

A man taking simvastatin develops severe muscle pain, muscle inflammation, And dark urine after beginning concurrent therapy with another drug.Which agent is most likely responsible for this adverse drug interaction?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiviral Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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