Question 1

Which of the following are NOT identified during annotation?

Accepted Answer

A)  protein-coding genes 
B)  noncoding RNA genes 
C)  origins of replication 
D)  protein interactions 
A)  protein-coding genes 
B)  noncoding RNA genes 
C)  origins of replication 
D)  protein interactions

Question 2

Match the following techniques with the descriptions listed below.
-used to determine DNA sequence in an automated way

Accepted Answer

A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown 
A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown

Question 3

Which of these statements best describes pseudogenes?

Accepted Answer

A)  Most pseudogenes derived from protein-coding genes but are not recognized by their sequence similarities to functional genes. 
B)  Pseudogenes are short repetitive sequences. 
C)  Pseudogenes are not similar to functional genes at DNA sequence level. 
D)  Most pseudogenes are derived from protein-coding genes and are recognized by their sequence similarities to functional genes. 
A)  Most pseudogenes derived from protein-coding genes but are not recognized by their sequence similarities to functional genes. 
B)  Pseudogenes are short repetitive sequences. 
C)  Pseudogenes are not similar to functional genes at DNA sequence level. 
D)  Most pseudogenes are derived from protein-coding genes and are recognized by their sequence similarities to functional genes.

Question 4

Match each of the following terms with its correct definition.
-genomics

Accepted Answer

A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome 
A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome

Question 5

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below.
-proteomics

Accepted Answer

A) DNA 
B) mRNA/cDNA 
C) protein 
A) DNA 
B) mRNA/cDNA 
C) protein

Question 6

What is an open reading frame?

Accepted Answer

A)  the nucleotides between and including a start codon and an end codon in all chromosomes 
B)  the nucleotides between and including a start codon and an end codon, minus the introns 
C)  the nucleotides between and including a start codon and an end codon, minus the exons 
D)  the nucleotides between a start codon and end codon only in prokaryotes 
A)  the nucleotides between and including a start codon and an end codon in all chromosomes 
B)  the nucleotides between and including a start codon and an end codon, minus the introns 
C)  the nucleotides between and including a start codon and an end codon, minus the exons 
D)  the nucleotides between a start codon and end codon only in prokaryotes

Question 7

Which of the following involves comparing gene expression under a defined experimental condition with expression under a control condition?

Accepted Answer

A)  studies of gene activity using DNA microarrays 
B)  studies of gene activity using RNA microarrays 
C)  studies of gene activity using RNA analyses 
D)  studies of gene activity using DNA analyses 
A)  studies of gene activity using DNA microarrays 
B)  studies of gene activity using RNA microarrays 
C)  studies of gene activity using RNA analyses 
D)  studies of gene activity using DNA analyses

Question 8

Match the following techniques with the descriptions listed below.
-used to determine DNA sequence using dideoxynucleotides

Accepted Answer

A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown 
A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown

Question 9

Which of the following values is your genome size?

Accepted Answer

A)  S-value 
B)  G-value 
C)  C-value 
D)  D-value 
A)  S-value 
B)  G-value 
C)  C-value 
D)  D-value

Question 10

Comparative genomics is done to learn how genes and genomes have evolved. What are three different concepts that we have learned from comparative genomics?

Accepted Answer

By comparing genomes from different orga

Question 11

Which of the following is NOT a way to determine the function of annotated genes?

Accepted Answer

A)  looking for similar gene sequences of known function 
B)  examining the putative protein structure 
C)  using gene knockout experiments 
D)  finding a pseudogene for that gene 
A)  looking for similar gene sequences of known function 
B)  examining the putative protein structure 
C)  using gene knockout experiments 
D)  finding a pseudogene for that gene

Question 12

Which of the following is a difference between prokaryotic and eukaryotic genomes?

Accepted Answer

A)  Eukaryotic protein-coding genes typically lack introns, so more sophisticated algorithms must be used to identify such genes. 
B)  Eukaryotic protein-coding genes typically have introns, so more sophisticated algorithms must be used to identify such genes. 
C)  Because many genes have introns in prokaryotic genomes, searching for protein-coding ORFs is straightforward. 
D)  Because many genes have introns in prokaryotic genomes, searching for protein-coding ORFs is very difficult. 
A)  Eukaryotic protein-coding genes typically lack introns, so more sophisticated algorithms must be used to identify such genes. 
B)  Eukaryotic protein-coding genes typically have introns, so more sophisticated algorithms must be used to identify such genes. 
C)  Because many genes have introns in prokaryotic genomes, searching for protein-coding ORFs is straightforward. 
D)  Because many genes have introns in prokaryotic genomes, searching for protein-coding ORFs is very difficult.

Question 13

Over half of your DNA sequence is comprised of transposable elements that were once mobile. Which of these statements best identifies such sequences?

Accepted Answer

A)  They contain genes that encompass about 15% to 25% of your genome. 
B)  They contain genes that are not coding for human proteins, and are called "junk DNA." 
C)  They contain genes that are coding for human proteins, but they are not expressed. 
D)  They do not contain genes, and are called "junk DNA." 
A)  They contain genes that encompass about 15% to 25% of your genome. 
B)  They contain genes that are not coding for human proteins, and are called "junk DNA." 
C)  They contain genes that are coding for human proteins, but they are not expressed. 
D)  They do not contain genes, and are called "junk DNA."

Exam 15: Genomes

Which of the following are NOT identified during annotation?

Match the following techniques with the descriptions listed below. -used to determine DNA sequence in an automated way

Which of these statements best describes pseudogenes?

Match each of the following terms with its correct definition. -genomics

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -proteomics

What is an open reading frame?

Which of the following involves comparing gene expression under a defined experimental condition with expression under a control condition?

Match the following techniques with the descriptions listed below. -used to determine DNA sequence using dideoxynucleotides

Which of the following values is your genome size?

Comparative genomics is done to learn how genes and genomes have evolved. What are three different concepts that we have learned from comparative genomics?

Which of the following is NOT a way to determine the function of annotated genes?

Which of the following is a difference between prokaryotic and eukaryotic genomes?

Over half of your DNA sequence is comprised of transposable elements that were once mobile. Which of these statements best identifies such sequences?

Light and Life

The Cell: an Overview

Energy and Enzymes

Cell Membranes and Signaling

Cellular Respiration

Photosynthesis

Cell Cycles

Genetic Recombination

The Chromosomal Basis of Mendelian Inheritance

Genetic Linkage, Sex-Linkage, and Other Non-Mendelian Inheritance Mechanisms

DNA Structure, Replication, and Repair

Gene Structure Expression, and Mutation

Regulation of Gene Expression

Dna Technologies

Evolution: the Development of the Theory

Microevolution: Changes Within Populations

Speciation and Macroevolution

Systematics and Phylogenetics: Revealing the Tree of Life

Humans and Evolution

Defining Life and Its Origins

Viruses, Viroids, and Prions: Infectious Biological Particles

Bacteria and Archaea

Protists

Fungi

Plants

Animals

Conservation of Biodiversity

Population Ecology

Species Interactions and Community Ecology

Ecosystems

Animal Behaviour

Organization of the Plant Body

Transport in Plants

Reproduction and Development in Flowering Plants

Plant Nutrition

Plant Signals and Responses to the Environment

Introduction to Animal Organization and Physiology

Animal Nutrition

Gas Exchange: the Respiratory System

Internal Transport: the Circulatory System

Regulation of the Internal Environment: Water, Solutes, and Temperature

Control of Animal Processes: Endocrine Control

Animal Reproduction

Control of Animal Processes: Neural Control

Muscles, Skeletons, and Body Movements

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