Question 1

How many ATP equivalents are produced from the total oxidation of one pyruvate to three CO2?

Accepted Answer

The total oxidation of one pyruvate by p

Question 2

________________ is the first citric acid cycle intermediate to be oxidized.

Accepted Answer

The answer of ________________ is the first citric acid cycle...

Question 3

In general, the citric acid cycle is inhibited under ________ (high, low) energy conditions.

Accepted Answer

The answer of In general, the citric acid cycle is...

Question 4

Why is the isomerization of citrate to isocitrate a necessary step of the citric acid cycle?

Accepted Answer

Citrate is a tertiary alcohol

Question 5

What is/are the chemical change(s) involved in the conversion of citrate into isocitrate?

Accepted Answer

A)  hydration followed by dehydration 
B)  dehydration followed by hydration 
C)  oxidation followed by reduction 
D)  reduction followed by oxidation 
E)  None of the answers is correct. 
A)  hydration followed by dehydration 
B)  dehydration followed by hydration 
C)  oxidation followed by reduction 
D)  reduction followed by oxidation 
E)  None of the answers is correct.

Question 6

What is the enzyme-bound intermediate in the conversion of citrate and isocitrate?

Accepted Answer

A)  oxalosuccinate 
B)  dihydrocitrate 
C)  cis-aconitate 
D)  hydroxyethyl-TPP 
E)  fumarate 
A)  oxalosuccinate 
B)  dihydrocitrate 
C)  cis-aconitate 
D)  hydroxyethyl-TPP 
E)  fumarate

Question 7

E1 of the pyruvate dehydrogenase complex requires the coenzyme ________________ for proper activity.

Accepted Answer

thiamine p

Exam 17: The Citric Acid Cycle

How many ATP equivalents are produced from the total oxidation of one pyruvate to three CO2?

________________ is the first citric acid cycle intermediate to be oxidized.

In general, the citric acid cycle is inhibited under ________ (high, low) energy conditions.

Why is the isomerization of citrate to isocitrate a necessary step of the citric acid cycle?

What is/are the chemical change(s) involved in the conversion of citrate into isocitrate?

What is the enzyme-bound intermediate in the conversion of citrate and isocitrate?

E1 of the pyruvate dehydrogenase complex requires the coenzyme ________________ for proper activity.

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How many ATP equivalents are produced from the total oxidation of one pyruvate to three CO₂?