Question 1

How are palindromic RNA polymerase transcription termination signals thought to function?

Accepted Answer

In the palindromic region, the bases form a hairpin stem and loop structure that is followed by a series of U-A base pairs. It is theorized that the RNA polymerase stalls at the palindromic sequence, and the DNA template separates from the nascent RNA at this point due to the weak RNA-DNA duplex interactions in the UA rich region.

Question 2

The RNA polymerase can unwind approximately _______________ bases.

Accepted Answer

17

Question 3

The _______________ subunit of RNA polymerase recognizes promoters during heat-shock conditions.

Accepted Answer

σ<sup>32</sup>

Question 4

Which DNA strand has the same sequence as the RNA transcript (except for thymine in place of uracil)?

Accepted Answer

A)  template strand 
B)  complementary strand 
C)  coding strand 
D)  copy strand 
E)  None of the answers is correct. 
A)  template strand 
B)  complementary strand 
C)  coding strand 
D)  copy strand 
E)  None of the answers is correct.

Question 5

Many eukaryotic promoters contain

Accepted Answer

A)  a TATAAT box near -10. 
B)  a TATA site near -30 to -100. 
C)  a CAAT site near -40 to -150. 
D)  a TATAAT box near -10 and a TATA site near -30 to -100. 
E)  a TATA site near -30 to -100 and a CAAT site near -40 to -150. 
A)  a TATAAT box near -10. 
B)  a TATA site near -30 to -100. 
C)  a CAAT site near -40 to -150. 
D)  a TATAAT box near -10 and a TATA site near -30 to -100. 
E)  a TATA site near -30 to -100 and a CAAT site near -40 to -150.

Question 6

What is the significance of the $\sigma$ subunit?

Accepted Answer

The @#LAT-DLM& subunit contributes to initiation i

Question 7

The rate of RNA synthesis in E. coli is approximately _______________ nucleotides per second.

Accepted Answer

The answer of The rate of RNA synthesis in E....

Question 8

How does the antibiotic rifamycin function?

Accepted Answer

Rifamycin functions by interfe

Question 9

Which of the following modifications are made to eukaryotic tRNA transcripts?

Accepted Answer

A)  modification of base and ribose moieties 
B)  removal of 3′ trailer 
C)  cleavage of 5′ leader by RNase P 
D)  CCA is added. 
E)  All the answers are correct. 
A)  modification of base and ribose moieties 
B)  removal of 3′ trailer 
C)  cleavage of 5′ leader by RNase P 
D)  CCA is added. 
E)  All the answers are correct.

Question 10

What is present in the spliceosome complex?

Accepted Answer

The spliceosome comp

Question 11

Which of the following is a mechanism of splicing that allows diversity in the proteins generated from a particular gene?

Accepted Answer

A)  crossover 
B)  mRNA recombination 
C)  recombinase-assisted splicing 
D)  translocation 
E)  alternative splicing 
A)  crossover 
B)  mRNA recombination 
C)  recombinase-assisted splicing 
D)  translocation 
E)  alternative splicing

Question 12

What complex is responsible for splicing mRNA precursors?

Accepted Answer

A)  splicozyme 
B)  spliceosome 
C)  sRNA 
D)  splicicon 
E)  None of the answers is correct. 
A)  splicozyme 
B)  spliceosome 
C)  sRNA 
D)  splicicon 
E)  None of the answers is correct.

Question 13

What is the mechanism by which drugs such as actinomycin D slip between the bases of the DNA helix?

Accepted Answer

A)  insertion 
B)  intercalation 
C)  incorporation 
D)  addition 
E)  substitution 
A)  insertion 
B)  intercalation 
C)  incorporation 
D)  addition 
E)  substitution

Question 14

Which of the following changes the nucleotide sequence of RNA after transcription occurs, by processes other than RNA splicing?

Accepted Answer

A)  RNA editing 
B)  RNA proofing 
C)  RNA substitution 
D)  RNA mutation 
E)  None of the answers is correct. 
A)  RNA editing 
B)  RNA proofing 
C)  RNA substitution 
D)  RNA mutation 
E)  None of the answers is correct.

Question 15

Name the three stages of RNA synthesis.

Accepted Answer

The three stages of

Question 16

Describe some of the significant differences between eukaryotic and prokaryotic transcription and translation.

Accepted Answer

In eukaryotes, the two processes are sep

Question 17

Approximately how many mRNA transcripts in higher eukaryotes undergo processing?

Accepted Answer

Nearly all mRNA prec

Question 18

The template strand has the _______________ sequence as the RNA transcript (except T instead of U).

Accepted Answer

The answer of The template strand has the _______________ sequence...

Question 19

tRNA and rRNA modification in prokaryotes includes

Accepted Answer

A)  cleavage and modification of nascent RNA. 
B)  addition of nucleotides. 
C)  spliceosome-mediated splicing of the nascent RNA. 
D)  All the answers are correct. 
E)  cleavage and modification of nascent RNA and addition of nucleotides. 
A)  cleavage and modification of nascent RNA. 
B)  addition of nucleotides. 
C)  spliceosome-mediated splicing of the nascent RNA. 
D)  All the answers are correct. 
E)  cleavage and modification of nascent RNA and addition of nucleotides.

Question 20

The rho (ρ) protein terminates transcription by acting as a ________________.

Accepted Answer

The answer of The rho (ρ) protein terminates transcription by...

Exam 29: Rna Synthesis and Processing

How are palindromic RNA polymerase transcription termination signals thought to function?

The RNA polymerase can unwind approximately _______________ bases.

The _______________ subunit of RNA polymerase recognizes promoters during heat-shock conditions.

Which DNA strand has the same sequence as the RNA transcript (except for thymine in place of uracil)?

Many eukaryotic promoters contain

What is the significance of the σ\sigmaσ subunit?

The rate of RNA synthesis in E. coli is approximately _______________ nucleotides per second.

How does the antibiotic rifamycin function?

Which of the following modifications are made to eukaryotic tRNA transcripts?

What is present in the spliceosome complex?

Which of the following is a mechanism of splicing that allows diversity in the proteins generated from a particular gene?

What complex is responsible for splicing mRNA precursors?

What is the mechanism by which drugs such as actinomycin D slip between the bases of the DNA helix?

Which of the following changes the nucleotide sequence of RNA after transcription occurs, by processes other than RNA splicing?

Name the three stages of RNA synthesis.

Describe some of the significant differences between eukaryotic and prokaryotic transcription and translation.

Approximately how many mRNA transcripts in higher eukaryotes undergo processing?

The template strand has the _______________ sequence as the RNA transcript (except T instead of U).

tRNA and rRNA modification in prokaryotes includes

The rho (ρ) protein terminates transcription by acting as a ________________.

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

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What is the significance of the $\sigma$ subunit?