Question 1

There are approximately _______________ promoter sites found in the E. coli genome.

Accepted Answer

The answer of There are approximately _______________ promoter sites found...

Question 2

A _______________ sequence is determined by an alignment of multiple DNA base sequences and is a recurring pattern or motif.

Accepted Answer

The answer of A _______________ sequence is determined by an...

Question 3

Which of the following is an RNA molecule that is catalytic?

Accepted Answer

A)  tRNA 
B)  ribonuclease 
C)  ribozyme 
D)  RNA helicase 
E)  None of the answers is correct. 
A)  tRNA 
B)  ribonuclease 
C)  ribozyme 
D)  RNA helicase 
E)  None of the answers is correct.

Question 4

Functions of RNA polymerase include

Accepted Answer

A)  searching for promoter sites. 
B)  unwinding short stretches of DNA. 
C)  detecting termination signals. 
D)  All the answers are correct. 
E)  searching for promoter sites and detecting termination signals. 
A)  searching for promoter sites. 
B)  unwinding short stretches of DNA. 
C)  detecting termination signals. 
D)  All the answers are correct. 
E)  searching for promoter sites and detecting termination signals.

Question 5

What are the two types of self-splicing introns?

Accepted Answer

They are divided into group I and group

Question 6

RNA polymerase I transcribes the genes for

Accepted Answer

A)  mRNA precursors. 
B)  18S, 5.8 S, and 28S rRNA. 
C)  most tRNA. 
D)  All the answers are correct. 
E)  None of the answers is correct. 
A)  mRNA precursors. 
B)  18S, 5.8 S, and 28S rRNA. 
C)  most tRNA. 
D)  All the answers are correct. 
E)  None of the answers is correct.

Question 7

The chemical reaction(s) in RNA splicing include

Accepted Answer

A)  two transesterifications. 
B)  one transesterification. 
C)  one transesterification and an oxidation. 
D)  two oxidations. 
E)  None of the answers is correct. 
A)  two transesterifications. 
B)  one transesterification. 
C)  one transesterification and an oxidation. 
D)  two oxidations. 
E)  None of the answers is correct.

Question 8

How does RNA polymerase find the proper binding site?

Accepted Answer

The RNA polymerase b

Question 9

RNA self-splicing demonstrates the role of RNA as a __________________.

Accepted Answer

The answer of RNA self-splicing demonstrates the role of RNA...

Question 10

How does binding of heat-shock proteins differ between E. coli and Drosophila?

Accepted Answer

Heat-shock transcription factor (HSTF) i

Question 11

What name is given to the region of RNA synthesis that contains the DNA, RNA, and RNA polymerase?

Accepted Answer

A)  transcription fork 
B)  replicon 
C)  transcriptosome 
D)  transcription bubble 
E)  transcription complex 
A)  transcription fork 
B)  replicon 
C)  transcriptosome 
D)  transcription bubble 
E)  transcription complex

Question 12

The carboxyl-terminal domain (CTD) of RNA polymerase II is involved in

Accepted Answer

A)  binding to promoter regions of DNA. 
B)  formation of the transcription bubble. 
C)  coordinating post-transcriptional processing events. 
D)  recognition of the termination signal. 
E)  None of the answers is correct. 
A)  binding to promoter regions of DNA. 
B)  formation of the transcription bubble. 
C)  coordinating post-transcriptional processing events. 
D)  recognition of the termination signal. 
E)  None of the answers is correct.

Question 13

Many genetic diseases are caused by mutations that affect RNA __________.

Accepted Answer

The answer of Many genetic diseases are caused by mutations...

Question 14

Proteins that possess alternative splicing products include

Accepted Answer

A)  calcitonin. 
B)  hemoglobin β. 
C)  apolipoprotein. 
D)  calcitonin and apolipoprotein. 
E)  hemoglobin β and apolipoprotein. 
A)  calcitonin. 
B)  hemoglobin β. 
C)  apolipoprotein. 
D)  calcitonin and apolipoprotein. 
E)  hemoglobin β and apolipoprotein.

Question 15

Actinomycin interferes with transcription by binding to

Accepted Answer

A)  the RNA polymerase. 
B)  the DNA-RNA duplex. 
C)  the DNA helix and preventing its use as an RNA template. 
D)  σ subunits 
E)  None of the answers is correct. 
A)  the RNA polymerase. 
B)  the DNA-RNA duplex. 
C)  the DNA helix and preventing its use as an RNA template. 
D)  σ subunits 
E)  None of the answers is correct.

Question 16

The first event in eukaryotic transcriptional activation is binding of

Accepted Answer

A)  the TATA-box-binding protein (TBP) to the TATA box. 
B)  the SP-1 protein to the CAAT box. 
C)  the RNA polymerase 500 base pairs upstream of the CAAT and TATA boxes. 
D)  rho protein to DNA. 
E)  None of the answers is correct. 
A)  the TATA-box-binding protein (TBP) to the TATA box. 
B)  the SP-1 protein to the CAAT box. 
C)  the RNA polymerase 500 base pairs upstream of the CAAT and TATA boxes. 
D)  rho protein to DNA. 
E)  None of the answers is correct.

Question 17

A disease caused by mutations in pre-mRNA or in the splicing factors is

Accepted Answer

A)  Burkitt lymphoma. 
B)  thalassemia. 
C)  retinitis pigmentosa. 
D)  sickle-cell anemia. 
E)  None of the answers is correct. 
A)  Burkitt lymphoma. 
B)  thalassemia. 
C)  retinitis pigmentosa. 
D)  sickle-cell anemia. 
E)  None of the answers is correct.

Question 18

What are microRNAs, and what role do they play in gene regulation?

Accepted Answer

MicroRNAs are found in eukaryotes and ar

Question 19

What is the definition of a promoter?

Accepted Answer

A promoter is a sequence of DN

Question 20

Which of the following is required for DNA synthesis but not for RNA synthesis?

Accepted Answer

A)  polymerase 
B)  nucleotide triphosphates 
C)  DNA sequence that serves as a template 
D)  promoter 
E)  primer 
A)  polymerase 
B)  nucleotide triphosphates 
C)  DNA sequence that serves as a template 
D)  promoter 
E)  primer

Exam 29: Rna Synthesis and Processing

There are approximately _______________ promoter sites found in the E. coli genome.

A _______________ sequence is determined by an alignment of multiple DNA base sequences and is a recurring pattern or motif.

Which of the following is an RNA molecule that is catalytic?

Functions of RNA polymerase include

What are the two types of self-splicing introns?

RNA polymerase I transcribes the genes for

The chemical reaction(s) in RNA splicing include

How does RNA polymerase find the proper binding site?

RNA self-splicing demonstrates the role of RNA as a __________________.

How does binding of heat-shock proteins differ between E. coli and Drosophila?

What name is given to the region of RNA synthesis that contains the DNA, RNA, and RNA polymerase?

The carboxyl-terminal domain (CTD) of RNA polymerase II is involved in

Many genetic diseases are caused by mutations that affect RNA __________.

Proteins that possess alternative splicing products include

Actinomycin interferes with transcription by binding to

The first event in eukaryotic transcriptional activation is binding of

A disease caused by mutations in pre-mRNA or in the splicing factors is

What are microRNAs, and what role do they play in gene regulation?

What is the definition of a promoter?

Which of the following is required for DNA synthesis but not for RNA synthesis?

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

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