Question 1

_________________ is a poison because it blocks the flow of electrons from cytochrome c to oxygen.

Accepted Answer

Carbon monoxide (CO)

Question 2

Give the balanced equation for the net reaction catalyzed by Q-cytochrome c oxido-reducatase.

Accepted Answer

QH₂ + 2 Cyt c_o

Question 3

Which of the following does NOT participate in, nor is a component of, the electron-transport chain?

Accepted Answer

A)  lipoic acid 
B)  nonheme, iron-sulfur proteins 
C)  FADH2 
D)  cytochrome c1 
E)  NADH 
A)  lipoic acid 
B)  nonheme, iron-sulfur proteins 
C)  FADH2 
D)  cytochrome c1 
E)  NADH

Question 4

In the initial step of Complex I, two high-potential electrons are transferred from NADH to the ___________ prosthetic group of this complex.

Accepted Answer

The answer of In the initial step of Complex I,...

Question 5

The transfer of a single electron to O2 forms the reactive _______________ ion.

Accepted Answer

Question 6

What process allows cytoplasmic NADH to be reoxidized by O2 using the electron-transport system?

Accepted Answer

A)  glycerol 3-phosphate shuttle 
B)  cytochrome c shuttle 
C)  malate-aspartate shuttle 
D)  quinone shuttle 
E)  glycerol 3-phosphate shuttle and malate-aspartate shuttle 
A)  glycerol 3-phosphate shuttle 
B)  cytochrome c shuttle 
C)  malate-aspartate shuttle 
D)  quinone shuttle 
E)  glycerol 3-phosphate shuttle and malate-aspartate shuttle

Question 7

Electron flow down the electron-transport chain leads to the

Accepted Answer

A)  transport of protons across the inner mitochondrial membrane from inside the matrix to the intermembrane space. 
B)  transport of protons across the inner mitochondrial membrane from the intermembrane space into the matrix. 
C)  coupled synthesis of GTP. 
D)  a dangerous imbalance of K+ ions across the mitochondrial membrane. 
E)  None of the answers is correct. 
A)  transport of protons across the inner mitochondrial membrane from inside the matrix to the intermembrane space. 
B)  transport of protons across the inner mitochondrial membrane from the intermembrane space into the matrix. 
C)  coupled synthesis of GTP. 
D)  a dangerous imbalance of K+ ions across the mitochondrial membrane. 
E)  None of the answers is correct.

Question 8

Provide a brief description of oxidative phosphorylation.

Accepted Answer

It is the process in which ATP

Question 9

What type of protein makes the outer mitochondrial membrane relatively permeable?

Accepted Answer

A)  proton pump 
B)  voltage gated transporter 
C)  ATP-powered pump 
D)  porin 
E)  None of the answers is correct. 
A)  proton pump 
B)  voltage gated transporter 
C)  ATP-powered pump 
D)  porin 
E)  None of the answers is correct.

Question 10

What organelle is the site of oxidative phosphorylation in eukaryotes?

Accepted Answer

A)  mitochondria 
B)  chloroplast 
C)  lysosome 
D)  endoplasmic reticulum 
E)  Golgi apparatus 
A)  mitochondria 
B)  chloroplast 
C)  lysosome 
D)  endoplasmic reticulum 
E)  Golgi apparatus

Question 11

What evidence demonstrated the ATP synthase has components that can actually rotate?

Accepted Answer

@#LAT-DLM&₃@#LAT-DLM&₃@#LAT-DLM&F10 subunits wer

Question 12

What name is given to the hypothesis proposed by Peter Mitchell that explains how ATP synthesis is coupled to electron transport?

Accepted Answer

A)  chemiosmotic hypothesis 
B)  oxidative phosphorylation hypothesis 
C)  electron transport hypothesis 
D)  proton-motive force hypothesis 
E)  None of the answers is correct. 
A)  chemiosmotic hypothesis 
B)  oxidative phosphorylation hypothesis 
C)  electron transport hypothesis 
D)  proton-motive force hypothesis 
E)  None of the answers is correct.

Question 13

What prosthetic group is present in complexes I, II, and III of electron transport?

Accepted Answer

A)  semiquinone 
B)  flavin mononucleotide 
C)  coenzyme Q 
D)  heme group 
E)  iron-sulfur cluster 
A)  semiquinone 
B)  flavin mononucleotide 
C)  coenzyme Q 
D)  heme group 
E)  iron-sulfur cluster

Question 14

Which enzyme transfers electrons from a membrane-soluble carrier to a water-soluble carrier in the electron-transport process?

Accepted Answer

A)  ATP synthase 
B)  cytochrome c oxidase 
C)  NADH-Q oxidoreductase 
D)  Q-cytochrome c oxidoreductase 
E)  succinate-Q reductase 
A)  ATP synthase 
B)  cytochrome c oxidase 
C)  NADH-Q oxidoreductase 
D)  Q-cytochrome c oxidoreductase 
E)  succinate-Q reductase

Question 15

In the Rieske center, the iron-sulfur center is coordinated to the amino acid(s) _______.

Accepted Answer

A)  His 
B)  Cys 
C)  His and Cys 
D)  Cys and Met 
E)  None of the answers is correct. 
A)  His 
B)  Cys 
C)  His and Cys 
D)  Cys and Met 
E)  None of the answers is correct.

Question 16

The energy for ATP synthesis is generated by the movement of protons from the ______________ side of the inner mitochondrial membrane establishing a(an) _____________ gradient.

Accepted Answer

A)  intermembrane; pH 
B)  intermembrane; electrical potential 
C)  matrix; sodium ion 
D)  matrix; pH 
E)  None of the answers is correct. 
A)  intermembrane; pH 
B)  intermembrane; electrical potential 
C)  matrix; sodium ion 
D)  matrix; pH 
E)  None of the answers is correct.

Question 17

In the glycerol phosphate shuttle, cytoplasmic glycerol phosphate dehydrogenase uses cytoplasmic NADH to reduce _________________ to glycerol-3-phosphate.

Accepted Answer

dihydroxya

Question 18

What is the driving force for electron transport through the electron-transport chain?

Accepted Answer

NADH is a strong reducing agent and is p

Question 19

In the malate-aspartate shuttle, how is oxaloacetate regenerated since there is no transporter for oxaloacetate across the inner membrane?

Accepted Answer

Oxaloacetate is interconverted between m

Question 20

Describe the major defensive strategy that cells employ to prevent the harmful effects of the reactive oxygen species (ROS) that are inevitably produced during respiration.

Accepted Answer

The enzyme superoxide dismutase converts

Exam 18: Oxidative Phosphorylation

_________________ is a poison because it blocks the flow of electrons from cytochrome c to oxygen.

Give the balanced equation for the net reaction catalyzed by Q-cytochrome c oxido-reducatase.

Which of the following does NOT participate in, nor is a component of, the electron-transport chain?

In the initial step of Complex I, two high-potential electrons are transferred from NADH to the ___________ prosthetic group of this complex.

The transfer of a single electron to O2 forms the reactive _______________ ion.

What process allows cytoplasmic NADH to be reoxidized by O2 using the electron-transport system?

Electron flow down the electron-transport chain leads to the

Provide a brief description of oxidative phosphorylation.

What type of protein makes the outer mitochondrial membrane relatively permeable?

What organelle is the site of oxidative phosphorylation in eukaryotes?

What evidence demonstrated the ATP synthase has components that can actually rotate?

What name is given to the hypothesis proposed by Peter Mitchell that explains how ATP synthesis is coupled to electron transport?

What prosthetic group is present in complexes I, II, and III of electron transport?

Which enzyme transfers electrons from a membrane-soluble carrier to a water-soluble carrier in the electron-transport process?

In the Rieske center, the iron-sulfur center is coordinated to the amino acid(s) _______.

The energy for ATP synthesis is generated by the movement of protons from the ______________ side of the inner mitochondrial membrane establishing a(an) _____________ gradient.

In the glycerol phosphate shuttle, cytoplasmic glycerol phosphate dehydrogenase uses cytoplasmic NADH to reduce _________________ to glycerol-3-phosphate.

What is the driving force for electron transport through the electron-transport chain?

In the malate-aspartate shuttle, how is oxaloacetate regenerated since there is no transporter for oxaloacetate across the inner membrane?

Describe the major defensive strategy that cells employ to prevent the harmful effects of the reactive oxygen species (ROS) that are inevitably produced during respiration.

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Rna Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

The transfer of a single electron to O₂ forms the reactive _______________ ion.

What process allows cytoplasmic NADH to be reoxidized by O₂ using the electron-transport system?

The energy for ATP synthesis is generated by the movement of protons from the __ side of the inner mitochondrial membrane establishing a(an) _ gradient.