Question 1

Hydroxylation of cholesterol by cytochrome P450 requires

Accepted Answer

A)  NADPH. 
B)  O2 
C)  PLP. 
D)  thiamine. 
E)  NADPH and O2. 
A)  NADPH. 
B)  O2 
C)  PLP. 
D)  thiamine. 
E)  NADPH and O2.

Question 2

Feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme

Accepted Answer

A)  3-hydroxy-3-methylglutaryl CoA reductase. 
B)  geranyltransferase. 
C)  HMG transferase. 
D)  farnesyl reductase. 
E)  None of the answers is correct. 
A)  3-hydroxy-3-methylglutaryl CoA reductase. 
B)  geranyltransferase. 
C)  HMG transferase. 
D)  farnesyl reductase. 
E)  None of the answers is correct.

Question 3

What are the steps in LDL uptake into cells?

Accepted Answer

The LDL contains apolipoprotein B-100, w

Question 4

The first step in vitamin D synthesis is unusual. What is it?

Accepted Answer

The precursor to vitamin D is

Question 5

The LDL receptors on the plasma membrane are localized in coated pits that contain which of the following proteins?

Accepted Answer

A)  clathrin 
B)  lipoprotein B-100 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  SREBP, sterol regulatory element binding protein 
A)  clathrin 
B)  lipoprotein B-100 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  SREBP, sterol regulatory element binding protein

Question 6

In the biosynthesis of sphingosine, the condensation of palmitoyl CoA and serine requires the coenzyme ____________________.

Accepted Answer

PLP, pyrid

Question 7

List the types of lipoprotein particles, and give the primary physiological role of the lipoprotein.

Accepted Answer

The answer of List the types of lipoprotein particles, and...

Question 8

The highest concentration of sphingolipids is found in the

Accepted Answer

A)  central nervous system. 
B)  lymph system. 
C)  serum. 
D)  adipose tissue. 
E)  None of the answers is correct. 
A)  central nervous system. 
B)  lymph system. 
C)  serum. 
D)  adipose tissue. 
E)  None of the answers is correct.

Question 9

______________________ are sphingolipids that contain an oligosaccharide unit having at least one sialic acid residue.

Accepted Answer

The answer of ______________________ are sphingolipids that contain an oligosaccharide...

Question 10

What are the causes and symptoms of familial hypercholesterolemia?

Accepted Answer

The hallmark of this genetic disease is

Exam 26: Biosynthesis of Membrane Lipids and Steroids

Hydroxylation of cholesterol by cytochrome P450 requires

Feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme

What are the steps in LDL uptake into cells?

The first step in vitamin D synthesis is unusual. What is it?

The LDL receptors on the plasma membrane are localized in coated pits that contain which of the following proteins?

In the biosynthesis of sphingosine, the condensation of palmitoyl CoA and serine requires the coenzyme ____________________.

List the types of lipoprotein particles, and give the primary physiological role of the lipoprotein.

The highest concentration of sphingolipids is found in the

______________________ are sphingolipids that contain an oligosaccharide unit having at least one sialic acid residue.

What are the causes and symptoms of familial hypercholesterolemia?

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Rna Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

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