Question 1

In which type of inhibition does an inhibitor bind to an enzyme at a site other than the active site?

Accepted Answer

A)  cooperative inhibition 
B)  competitive inhibition 
C)  noncompetitive inhibition 
D)  selective inhibition 
A)  cooperative inhibition 
B)  competitive inhibition 
C)  noncompetitive inhibition 
D)  selective inhibition

Question 2

Which of the following enzymes is assayed to diagnose liver or bone disease?

Accepted Answer

A)  alkaline phosphatase 
B)  alkaline aminotransferase 
C)  acid phosphatase 
D)  lactate dehydrogenase 
A)  alkaline phosphatase 
B)  alkaline aminotransferase 
C)  acid phosphatase 
D)  lactate dehydrogenase

Question 3

Lactate dehydrogenase belongs to which group of enzymes?

Accepted Answer

A)  hydrolases 
B)  lyases 
C)  oxidoreductases 
D)  transferases 
A)  hydrolases 
B)  lyases 
C)  oxidoreductases 
D)  transferases

Question 4

Which term is used for an enzyme regulation process where the formation of a product inhibits an earlier reaction in the sequence?

Accepted Answer

A)  cooperative inhibition 
B)  competitive inhibition 
C)  feedback control 
D)  stereospecificity 
A)  cooperative inhibition 
B)  competitive inhibition 
C)  feedback control 
D)  stereospecificity

Question 5

Which of the following terms refers to nonprotein parts of enzymes that are necessary for catalytic function?

Accepted Answer

A)  apoenzyme 
B)  coenzyme 
C)  cofactor 
D)  substrate 
A)  apoenzyme 
B)  coenzyme 
C)  cofactor 
D)  substrate

Question 6

Which of the following enzymes is an example of a lyase?

Accepted Answer

A)  aconitase 
B)  acetylcholinesterase 
C)  aspartate transaminase 
D)  lactate dehydrogenase 
A)  aconitase 
B)  acetylcholinesterase 
C)  aspartate transaminase 
D)  lactate dehydrogenase

Question 7

Which disease is diagnosed by assaying acid phosphatase activity?

Accepted Answer

A)  hepatitis 
B)  liver cancer 
C)  pancreatic disease 
D)  prostate cancer 
A)  hepatitis 
B)  liver cancer 
C)  pancreatic disease 
D)  prostate cancer

Question 8

In which type of inhibition is it possible to restore the maximum rate of enzyme activity by adding additional substrate?

Accepted Answer

A)  cooperative inhibition 
B)  competitive inhibition 
C)  induced-fit inhibition 
D)  irreversible inhibition 
A)  cooperative inhibition 
B)  competitive inhibition 
C)  induced-fit inhibition 
D)  irreversible inhibition

Question 9

Aconitase belongs to which group of enzymes?

Accepted Answer

A)  hydrolases 
B)  lyases 
C)  oxidoreductases 
D)  transferases 
A)  hydrolases 
B)  lyases 
C)  oxidoreductases 
D)  transferases

Question 10

Examine the following graph.   Which of the following explains why the "line" on the graph does not continue in a linear fashion?

Accepted Answer

A)  All of the added substrate is bound to the enzyme. 
B)  All of the enzyme active sites are occupied. 
C)  The amount of enzyme present is greater than needed by the substrate. 
D)  An inhibitor is present. 
A)  All of the added substrate is bound to the enzyme. 
B)  All of the enzyme active sites are occupied. 
C)  The amount of enzyme present is greater than needed by the substrate. 
D)  An inhibitor is present.

Question 11

Which of the following changes gives a saturation curve for the rate of enzyme activity?

Accepted Answer

A)  an increase in enzyme concentration 
B)  an increase in substrate concentration 
C)  an increase in temperature 
D)  an increase in pH 
A)  an increase in enzyme concentration 
B)  an increase in substrate concentration 
C)  an increase in temperature 
D)  an increase in pH

Question 12

Consider the following graph for the rate of an enzyme catalyzed reaction.   What is the approximate optimum temperature for carrying out this reaction?

Accepted Answer

A)  20°C 
B)  25°C 
C)  35°C 
D)  45°C 
A)  20°C 
B)  25°C 
C)  35°C 
D)  45°C

Question 13

Consider the following reaction.   Which group of enzymes catalyzes this reaction?

Accepted Answer

A)  oxidoreductases 
B)  isomerases 
C)  transferases 
D)  ligases 
E)  hydrolases 
A)  oxidoreductases 
B)  isomerases 
C)  transferases 
D)  ligases 
E)  hydrolases

Question 14

Which term refers to a species that can reversibly bind to an allosteric enzyme?

Accepted Answer

A)  a zymogen 
B)  an isozyme 
C)  a cofactor 
D)  a regulator 
A)  a zymogen 
B)  an isozyme 
C)  a cofactor 
D)  a regulator

Question 15

Which of the following enzymes is assayed to diagnose infectious hepatitis?

Accepted Answer

A)  ALT 
B)  CPK 
C)  LDH 
D)  PHI 
A)  ALT 
B)  CPK 
C)  LDH 
D)  PHI

Question 16

Which of the following statements is true of enzymes?

Accepted Answer

A)  All enzymes are fibrous proteins. 
B)  All enzymes are globular proteins. 
C)  The majority of enzymes are fibrous proteins. 
D)  The majority of enzymes are globular proteins. 
A)  All enzymes are fibrous proteins. 
B)  All enzymes are globular proteins. 
C)  The majority of enzymes are fibrous proteins. 
D)  The majority of enzymes are globular proteins.

Question 17

Consider the following two images depicting enzyme behavior.   Which image provides a better explanation for the induced-fit model?

Accepted Answer

A)  A only 
B)  B only 
C)  Both A and B 
A)  A only 
B)  B only 
C)  Both A and B

Question 18

Which of following statements is true of urease?

Accepted Answer

A)  It catalyzes the degradation of uracil. 
B)  It catalyzes the synthesis of urea. 
C)  It catalyzes the hydrolysis of urea. 
D)  It catalyzes the hydrolysis of all amines. 
A)  It catalyzes the degradation of uracil. 
B)  It catalyzes the synthesis of urea. 
C)  It catalyzes the hydrolysis of urea. 
D)  It catalyzes the hydrolysis of all amines.

Question 19

Which of the following statements is true of trypsin?

Accepted Answer

A)  It does not affect any peptide bond. 
B)  It hydrolyzes all peptide bonds. 
C)  It hydrolyzes peptide bonds only on the carboxyl side of leucine and phenylalanine residues. 
D)  It hydrolyzes peptide bonds only on the carboxyl side of arginine and lysine residues. 
A)  It does not affect any peptide bond. 
B)  It hydrolyzes all peptide bonds. 
C)  It hydrolyzes peptide bonds only on the carboxyl side of leucine and phenylalanine residues. 
D)  It hydrolyzes peptide bonds only on the carboxyl side of arginine and lysine residues.

Question 20

Identify the optimum pH for the activity of the enzyme lactase.

Accepted Answer

A)  2.0 
B)  9.0 
C)  10.0 
D)  6.0 
A)  2.0 
B)  9.0 
C)  10.0 
D)  6.0

Exam 22: Enzymes

In which type of inhibition does an inhibitor bind to an enzyme at a site other than the active site?

Which of the following enzymes is assayed to diagnose liver or bone disease?

Lactate dehydrogenase belongs to which group of enzymes?

Which term is used for an enzyme regulation process where the formation of a product inhibits an earlier reaction in the sequence?

Which of the following terms refers to nonprotein parts of enzymes that are necessary for catalytic function?

Which of the following enzymes is an example of a lyase?

Which disease is diagnosed by assaying acid phosphatase activity?

In which type of inhibition is it possible to restore the maximum rate of enzyme activity by adding additional substrate?

Aconitase belongs to which group of enzymes?

Examine the following graph. Which of the following explains why the "line" on the graph does not continue in a linear fashion?

Which of the following changes gives a saturation curve for the rate of enzyme activity?

Consider the following graph for the rate of an enzyme catalyzed reaction. What is the approximate optimum temperature for carrying out this reaction?

Consider the following reaction. Which group of enzymes catalyzes this reaction?

Which term refers to a species that can reversibly bind to an allosteric enzyme?

Which of the following enzymes is assayed to diagnose infectious hepatitis?

Which of the following statements is true of enzymes?

Consider the following two images depicting enzyme behavior. Which image provides a better explanation for the induced-fit model?

Which of following statements is true of urease?

Which of the following statements is true of trypsin?

Identify the optimum pH for the activity of the enzyme lactase.

Matter, Energy, and Measurement

Atoms

Chemical Bonds

Chemical Reactions

Gases, Liquids, and Solids

Solutions and Colloids

Reaction Rates and Chemical Equilibrium

Acids and Bases

Nuclear Chemistry

Organic Chemistry

Alkanes

Alkenes, Alkynes, and Aromatic Compounds

Alcohols, Ethers, and Thiols

Chirality: the Handedness of Molecules

Amines

Aldehydes and Ketones

Carboxylic Acids

Carboxylic Anhydrides, Esters, and Amides

Carbohydrates

Lipids

Proteins

Chemical Communications: Neurotransmitters and Hormones

Nucleotides, Nucleic Acids, and Heredity

Gene Expression and Protein Synthesis

Bioenergetics: How the Body Converts Food to Energy

Specific Catabolic Pathways: Carbohydrate, Lipid, and Protein Metabolism

Biosynthetic Pathways

Nutrition

Immunochemistry

Body Fluids

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