Exam 18: Regulation of Gene Expression

Transcription factors in eukaryotes usually have DNA binding domains as well as other domains that are also specific for binding. In general, which of the following would you expect many of them to be able to bind?

A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. -In one set of experiments she succeeded in decreasing methylation of histone tails. Which of the following results would she most likely see?

Most repressor proteins are allosteric. Which of the following binds with the repressor to alter its conformation?

During DNA replication,

Absence of bicoid mRNA from a Drosophila egg leads to the absence of anterior larval body parts and mirror-image duplication of posterior parts. This is evidence that the product of the bicoid gene

Tumor-suppressor genes

Which of the following is a protein produced by a regulatory gene?

Use the following information to answer the following questions. In Drosophila after ~100 minutes postfertilization, the embryo looks like the following diagram, with all nuclei having moved to the periphery and, subsequently, four of the nuclei being sequestered at the posterior end. Drosophila embryo after about 2 hours. -The four sequestered cells at one end are most probably destined to become

In eukaryotes, general transcription factors

Use the following information to answer the following questions. In Drosophila after ~100 minutes postfertilization, the embryo looks like the following diagram, with all nuclei having moved to the periphery and, subsequently, four of the nuclei being sequestered at the posterior end. Drosophila embryo after about 2 hours. -The next step after the embryo is formed would be

The role of a metabolite that controls a repressible operon is to

If you were to observe the activity of methylated DNA, you would expect it to

Genomic imprinting, DNA methylation, and histone acetylation are all examples of

In positive control of several sugar-metabolism-related operons, the catabolite activator protein (CAP)binds to DNA to stimulate transcription. What causes an increase in CAP?

What do gap genes, pair-rule genes, segment polarity genes, and homeotic genes all have in common?

Which of the following best describes siRNA?

For a repressible operon to be transcribed, which of the following must occur?

Within a cell, the amount of protein made using a given mRNA molecule depends partly on

Which of the following is characteristic of the product of the p53 gene?