Question 1

Domestication had what genetic effects on Maize compared to Teosinte?

Accepted Answer

A)  domestication had no genetic effect on Maize 
B)  domestication increased the number of genes in Maize 
C)  domestication decreased the number of genes in Maize 
D)  domestication increased the diversity of Maize 
E)  domestication decreased the diversity of Maize 
A)  domestication had no genetic effect on Maize 
B)  domestication increased the number of genes in Maize 
C)  domestication decreased the number of genes in Maize 
D)  domestication increased the diversity of Maize 
E)  domestication decreased the diversity of Maize

Question 2

Phenylketonuria (PKU) is detected in newborns when_________ are measured in blood samples.

Accepted Answer

A)  maternal cells 
B)  single nucleotide polymorphisms (SNPs) 
C)  chromosome abnormalities 
D)  metabolites 
E)  triplet repeat expansions 
A)  maternal cells 
B)  single nucleotide polymorphisms (SNPs) 
C)  chromosome abnormalities 
D)  metabolites 
E)  triplet repeat expansions

Question 3

The discovery of non- coding sequences that are conserved in a wide range of related species suggests that these sequences are important for what?

Accepted Answer

A)  cancer 
B)  the differences between those related species 
C)  migration 
D)  gene regulation 
E)  cell division 
A)  cancer 
B)  the differences between those related species 
C)  migration 
D)  gene regulation 
E)  cell division

Question 4

The recommended uniform screening panel (RUSP) includes tests for conditions that have all of the following characteristics except________ .

Accepted Answer

A)  treating the condition is not possible 
B)  the test can be performed with a blood sample 
C)  the condition must be reliably detected by the test 
D)  the condition can be treated by medical intervention 
E)  the condition can be dominant 
A)  treating the condition is not possible 
B)  the test can be performed with a blood sample 
C)  the condition must be reliably detected by the test 
D)  the condition can be treated by medical intervention 
E)  the condition can be dominant

Question 5

A proto- oncogene has what characteristics?

Accepted Answer

A)  a gene that inhibits cell division and when functioning normally, leads to cancer progression 
B)  a gene that inhibits apoptosis and when mutated prevents tumor metastasis 
C)  a gene that regulates the cell cycle in response to hormones 
D)  a gene that promotes cell division and when functioning normally, leads to cancer progression 
E)  a gene that promotes cell division and, when mutated, leads to cancer progression 
A)  a gene that inhibits cell division and when functioning normally, leads to cancer progression 
B)  a gene that inhibits apoptosis and when mutated prevents tumor metastasis 
C)  a gene that regulates the cell cycle in response to hormones 
D)  a gene that promotes cell division and when functioning normally, leads to cancer progression 
E)  a gene that promotes cell division and, when mutated, leads to cancer progression

Question 6

Non- invasive prenatal genetic screening capable of analyzing the nucleotide sequence of DNA includes which technique(s)?

Accepted Answer

A)  fetal cell sorting 
B)  amniocentesis 
C)  preimplantation screening 
D)  chorionic villus sampling 
E)  karyotying 
A)  fetal cell sorting 
B)  amniocentesis 
C)  preimplantation screening 
D)  chorionic villus sampling 
E)  karyotying

Question 7

Genetic health risk assessment data can be used to report all of the following except?

Accepted Answer

A)  a parents risk of passing on a disease- associated allele to their children 
B)  the contribution of the tested alleles to an individuals risk of developing a particular disorder 
C)  the presence of a disease- associated allele in an individual 
D)  the frequency of the disease causing allele in the population 
E)  an individuals exposure to tobacco 
A)  a parents risk of passing on a disease- associated allele to their children 
B)  the contribution of the tested alleles to an individuals risk of developing a particular disorder 
C)  the presence of a disease- associated allele in an individual 
D)  the frequency of the disease causing allele in the population 
E)  an individuals exposure to tobacco

Question 8

Alzheimer disease is associated with variation in the gene APOE. Thus, individuals with APOE mutations are _______.

Accepted Answer

A)  less likely to have parents who have/had Alzheimer disease 
B)  certain to have Alzheimer disease 
C)  more likely to respond to drugs that treat Alzheimer disease than individuals without APOE mutations 
D)  more likely to get Alzheimer disease than individuals without APOE mutations 
E)  less likely to have children who are susceptible to Alzheimer disease 
A)  less likely to have parents who have/had Alzheimer disease 
B)  certain to have Alzheimer disease 
C)  more likely to respond to drugs that treat Alzheimer disease than individuals without APOE mutations 
D)  more likely to get Alzheimer disease than individuals without APOE mutations 
E)  less likely to have children who are susceptible to Alzheimer disease

Question 9

A family with two unaffected parents and a child with a recessive disease would like to know what the probability is that one of their unaffected children might be a carrier. What do you tell them?

Accepted Answer

A)  the chance that an unaffected child is a carrier is less than 50% 
B)  the chance that an unaffected child is a carrier is 2/3 
C)  the chance that an unaffected child is a carrier is 0% 
D)  the chance that an unaffected child is a carrier is 75% 
E)  the chance that an unaffected child is a carrier is 50% 
A)  the chance that an unaffected child is a carrier is less than 50% 
B)  the chance that an unaffected child is a carrier is 2/3 
C)  the chance that an unaffected child is a carrier is 0% 
D)  the chance that an unaffected child is a carrier is 75% 
E)  the chance that an unaffected child is a carrier is 50%

Question 10

The presence of similar DNA sequences in sharks, whales and humans, but not in chimpanzees suggests?

Accepted Answer

A)  the DNA codes for a protein 
B)  that humans are derived from chimpanzees 
C)  the DNA was gained in elephants, mice and humans, but not chimpanzees . 
D)  the DNA was lost in chimpanzees 
E)  none of these hypotheses is supported by this observation 
A)  the DNA codes for a protein 
B)  that humans are derived from chimpanzees 
C)  the DNA was gained in elephants, mice and humans, but not chimpanzees . 
D)  the DNA was lost in chimpanzees 
E)  none of these hypotheses is supported by this observation

Question 11

________allows doctors to intervene in cases of rare disease to mitigate disease, often by simply prescribing dietary supplementation or restricting certain substances from the diet of affected individuals

Accepted Answer

A)  Direct- to- consumer genetic testing 
B)  Carrier testing 
C)  Population testing 
D)  Paternity testing 
E)  Newborn testing 
A)  Direct- to- consumer genetic testing 
B)  Carrier testing 
C)  Population testing 
D)  Paternity testing 
E)  Newborn testing

Question 12

Unlike many other genetic disorders, Huntington's disease is caused by a full penetrance disease allele. Full penetrance means what?

Accepted Answer

A)  The longer the allele (more triplet repeats), the more likely the disease is to occur in an individual. 
B)  Individuals with a disease allele are almost certain to get Huntington's disease. 
C)  Heterozygotes are just as likely to get Huntington's disease as homozygotes. 
D)  There are environmental factors beyond age that are also required for an individual to get Huntington's disease. 
E)  There are other genes that are also required for an individual to get Huntington's disease. 
A)  The longer the allele (more triplet repeats), the more likely the disease is to occur in an individual. 
B)  Individuals with a disease allele are almost certain to get Huntington's disease. 
C)  Heterozygotes are just as likely to get Huntington's disease as homozygotes. 
D)  There are environmental factors beyond age that are also required for an individual to get Huntington's disease. 
E)  There are other genes that are also required for an individual to get Huntington's disease.

Question 13

Genealogical analysis considers all of the following except?

Accepted Answer

A)  place of birth 
B)  the extent of shared SNPs between individuals 
C)  the frequency of alleles in reference populations 
D)  date of birth 
E)  the genotype of the tested individual 
A)  place of birth 
B)  the extent of shared SNPs between individuals 
C)  the frequency of alleles in reference populations 
D)  date of birth 
E)  the genotype of the tested individual

Question 14

A genetic counselor _______.

Accepted Answer

A)  chooses the best course of action for patients based on genetic testing 
B)  designs genetic tests that can be used in population- level testing programs 
C)  performs genetic testing and reports their findings to a medical doctor 
D)  performs gene therapy 
E)  helps patients choose whether or not they will undergo genetic testing, explains the results of genetic tests, and helps patients make their own medical decisions 
A)  chooses the best course of action for patients based on genetic testing 
B)  designs genetic tests that can be used in population- level testing programs 
C)  performs genetic testing and reports their findings to a medical doctor 
D)  performs gene therapy 
E)  helps patients choose whether or not they will undergo genetic testing, explains the results of genetic tests, and helps patients make their own medical decisions

Question 15

All of the following are expected to increase genetic diversity in a population except?

Accepted Answer

A)  random mating 
B)  immigration 
C)  small population size 
D)  low selective pressure 
E)  large population size 
A)  random mating 
B)  immigration 
C)  small population size 
D)  low selective pressure 
E)  large population size

Question 16

A couple comes to you for advice about genetic testing for a rare early- onset dominant condition. The paternal grandfather had the condition, but no one else in the family has had it including the male partner in this couple. Do you recommend testing? Why?

Accepted Answer

A)  yes, testing is expensive, but worth the price, even when unnecessary 
B)  no, the male partner is definitely a carrier and so the outcome is certain 
C)  yes, the male partner is definitely a carrier 
D)  no, we can deduce that neither partner has a disease allele 
E)  no, both parents would have to have the disease allele to have an affected child 
A)  yes, testing is expensive, but worth the price, even when unnecessary 
B)  no, the male partner is definitely a carrier and so the outcome is certain 
C)  yes, the male partner is definitely a carrier 
D)  no, we can deduce that neither partner has a disease allele 
E)  no, both parents would have to have the disease allele to have an affected child

Question 17

Cancer cells can divide indefinitely, which is also known as________ .

Accepted Answer

A)  mitotic arrest 
B)  cellular immortality 
C)  checkpoint function 
D)  resistance to cell death 
E)  cellular differentiation 
A)  mitotic arrest 
B)  cellular immortality 
C)  checkpoint function 
D)  resistance to cell death 
E)  cellular differentiation

Question 18

Cells whose normal function involves preventing cell division are generally characterized as__________ .

Accepted Answer

A)  transcription factors 
B)  apoptotic genes 
C)  oncogenes 
D)  pseudogenes 
E)  tumor suppressor genes 
A)  transcription factors 
B)  apoptotic genes 
C)  oncogenes 
D)  pseudogenes 
E)  tumor suppressor genes

Question 19

A boy with recessive X- linked hemophilia is born from an unaffected mother and a father with hemophilia. From which parent was the disease allele inherited?

Accepted Answer

A)  the father or the mother with an equal chance of either parent 
B)  the mother 
C)  the father 
D)  any of these answers is equally likely 
E)  both parents, the trait is recessive 
A)  the father or the mother with an equal chance of either parent 
B)  the mother 
C)  the father 
D)  any of these answers is equally likely 
E)  both parents, the trait is recessive

Question 20

CODIS markers are chosen that do not occur in coding regions of genes so that they do not disrupt what?

Accepted Answer

A)  promoters 
B)  intergenic regions 
C)  gene expression 
D)  introns 
E)  codons 
A)  promoters 
B)  intergenic regions 
C)  gene expression 
D)  introns 
E)  codons

Exam 21: Population Genetics and Evolution at the Population, Species, and Molecular Levels

Domestication had what genetic effects on Maize compared to Teosinte?

Phenylketonuria (PKU) is detected in newborns when_________ are measured in blood samples.

The discovery of non- coding sequences that are conserved in a wide range of related species suggests that these sequences are important for what?

The recommended uniform screening panel (RUSP) includes tests for conditions that have all of the following characteristics except________ .

A proto- oncogene has what characteristics?

Non- invasive prenatal genetic screening capable of analyzing the nucleotide sequence of DNA includes which technique(s)?

Genetic health risk assessment data can be used to report all of the following except?

Alzheimer disease is associated with variation in the gene APOE. Thus, individuals with APOE mutations are _______.

A family with two unaffected parents and a child with a recessive disease would like to know what the probability is that one of their unaffected children might be a carrier. What do you tell them?

The presence of similar DNA sequences in sharks, whales and humans, but not in chimpanzees suggests?

________allows doctors to intervene in cases of rare disease to mitigate disease, often by simply prescribing dietary supplementation or restricting certain substances from the diet of affected individuals

Unlike many other genetic disorders, Huntington's disease is caused by a full penetrance disease allele. Full penetrance means what?

Genealogical analysis considers all of the following except?

A genetic counselor _______.

All of the following are expected to increase genetic diversity in a population except?

A couple comes to you for advice about genetic testing for a rare early- onset dominant condition. The paternal grandfather had the condition, but no one else in the family has had it including the male partner in this couple. Do you recommend testing? Why?

Cancer cells can divide indefinitely, which is also known as________ .

Cells whose normal function involves preventing cell division are generally characterized as__________ .

A boy with recessive X- linked hemophilia is born from an unaffected mother and a father with hemophilia. From which parent was the disease allele inherited?

CODIS markers are chosen that do not occur in coding regions of genes so that they do not disrupt what?

The Molecular Basis of Heredity, Variation, and Evolution

Transmission Genetics

Cell Division and Chromosome Heredity

Inheritance Patterns of Single Genes and Gene Interaction

Genetic Linkage and Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophage

Dna Structure and Replication

Molecular Biology of Transcription and Rna Processing

The Molecular Biology of Translation

Chromosome Chapter Title Tbd

Gene Mutation, Dna Repair, and Homologous Recombination

Chromosome Chapter Title Tbd

Regulation of Gene Expression in Bacteria and Bacteriophage

Regulation of Gene Expression in Eukaryotes

Analysis of Gene Function by Forward Genetics and Reverse Genetics

Recombinant Dna Technology and Its Applications

Genomics: Genetics From a Whole-Genome Perspective

Organelle Inheritance and the Evolution of Organelle Genomes

Developmental Genetics

Genetic Analysis of Quantitative Traits

Filters