Exam 13: Translation and Proteins

Studies of Neurospora led to the ________ statement, whereas studies of human hemoglobin led to the statement.

The fi chain of adult hemoglobin is composed of 146 amino acids of a known sequence. In comparing the normal fi chain with the fi chain in sickle -cell hemoglobin, what alteration is one likely to find?

The secondary structure of a protein is dependent on polar interactions among the side chains of the amino acids.

Three major types of RNAs are mRNA, rRNA, and tRNA. For each of the conditions below, predict the consequences in terms of the population of proteins being synthesized in a particular cell. What qualitative and quantitative changes, if any, are expected in the individual protein involved (if one is involved) and in the population of proteins in this cell? a() a frameshift mutation in the heterozygous state b() a deletion of a significant proportion of ribosomal genes (rDNA)