Question 1

Who originally discovered the process of bacterial transformation?

Accepted Answer

A) Watson and Crick 
B) Chargaff 
C) Hershey and Chase 
D) Griffith 
E) Meselson and Stahl 
A) Watson and Crick 
B) Chargaff 
C) Hershey and Chase 
D) Griffith 
E) Meselson and Stahl

Question 2

Which of the following statements about DNA replication is false?

Accepted Answer

A) The two strands are separated. 
B) Each existing strand is used as a template for making a new strand. 
C) Synthesis of both new strands is in the 5' to 3' direction. 
D) The newly synthesized DNA is packaged into one nucleus,and the original DNA is packaged into another nucleus. 
A) The two strands are separated. 
B) Each existing strand is used as a template for making a new strand. 
C) Synthesis of both new strands is in the 5' to 3' direction. 
D) The newly synthesized DNA is packaged into one nucleus,and the original DNA is packaged into another nucleus.

Question 3

You take a sample of bacteria with DNA that contains only 14N and allow them to replicate in a medium that contains only 15N.After 3 rounds of replication,what percent of the DNA molecules will contain one strand with only 14N and one strand with only 15N? Enter your answer as a whole number without the percent sign.For example,5% would be entered as 5 and 37% would be entered as 37.

Accepted Answer

Question 4

An organism has been found to contain a defective form of photolyase.What function might be impaired in this organism?

Accepted Answer

A) Lengthening of the tips of chromosomes 
B) Repair of DNA damage caused by UV light 
C) Stabilization of single-stranded DNA during DNA replication 
D) Recognition of damaged DNA by the UvrABC complex 
A) Lengthening of the tips of chromosomes 
B) Repair of DNA damage caused by UV light 
C) Stabilization of single-stranded DNA during DNA replication 
D) Recognition of damaged DNA by the UvrABC complex

Question 5

Nucleotides have a phosphate group attached at the ________ carbon atom of the sugar.

Accepted Answer

A) 2' 
B) 3' 
C) 5' 
D) 1' 
A) 2' 
B) 3' 
C) 5' 
D) 1'

Question 6

The chemical bond connecting one nucleotide with the next along one strand of a DNA molecule is called a

Accepted Answer

A) glycosidic bond. 
B) hydrogen bond. 
C) phosphate bond. 
D) phosphodiester bond. 
E) peptide bond. 
A) glycosidic bond. 
B) hydrogen bond. 
C) phosphate bond. 
D) phosphodiester bond. 
E) peptide bond.

Question 7

The double helix model of DNA structure was proposed by

Accepted Answer

A) Watson and Crick. 
B) Griffith. 
C) Avery. 
D) Franklin. 
E) Chargaff. 
A) Watson and Crick. 
B) Griffith. 
C) Avery. 
D) Franklin. 
E) Chargaff.

Question 8

During DNA replication,each new strand begins with a short

Accepted Answer

A) amino acid primer. 
B) lipid primer. 
C) hydrophilic primer. 
D) DNA primer. 
E) RNA primer. 
A) amino acid primer. 
B) lipid primer. 
C) hydrophilic primer. 
D) DNA primer. 
E) RNA primer.

Question 9

If we think of the DNA double helix as a twisted ladder,what makes up the rungs or steps of the ladder?

Accepted Answer

A) phosphate groups only 
B) alternating phosphate groups and sugars 
C) sugars only 
D) purines and pyrimidines 
E) phosphate groups and bases 
A) phosphate groups only 
B) alternating phosphate groups and sugars 
C) sugars only 
D) purines and pyrimidines 
E) phosphate groups and bases

Question 10

After attaching to a bacterial cell,a bacteriophage typically

Accepted Answer

A) injects protein into the cell. 
B) extracts protein from the cell. 
C) injects DNA into the cell. 
D) extracts DNA from the cell. 
E) transforms the cell into a virulent strain. 
A) injects protein into the cell. 
B) extracts protein from the cell. 
C) injects DNA into the cell. 
D) extracts DNA from the cell. 
E) transforms the cell into a virulent strain.

Question 11

The synthesis of a growing strand of DNA is carried out by adding nucleotides to the ________ end of an existing strand.

Accepted Answer

A) 2' 
B) 3' 
C) 5' 
D) 1' 
A) 2' 
B) 3' 
C) 5' 
D) 1'

Question 12

Who demonstrated that phage genetic material is DNA and not protein?

Accepted Answer

A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick 
E) Avery,MacLeod,and McCarty 
A) Hershey and Chase 
B) Chargaff 
C) Franklin 
D) Watson and Crick 
E) Avery,MacLeod,and McCarty

Question 13

Avery,MacLeod,and McCarty's experiments revealed that the transforming principle had all of the following properties except

Accepted Answer

A) its activity was destroyed by treatment with proteases. 
B) its activity was unaffected by RNA-digesting enzymes. 
C) its activity was unaffected by lipid extraction. 
D) its activity was destroyed by treatment with DNA endonucleases. 
A) its activity was destroyed by treatment with proteases. 
B) its activity was unaffected by RNA-digesting enzymes. 
C) its activity was unaffected by lipid extraction. 
D) its activity was destroyed by treatment with DNA endonucleases.

Question 14

Replication of DNA is

Accepted Answer

A) conservative. 
B) redundant. 
C) dispersive. 
D) semiconservative. 
E) semidispersive. 
A) conservative. 
B) redundant. 
C) dispersive. 
D) semiconservative. 
E) semidispersive.

Question 15

Which is not a component of nucleic acids?

Accepted Answer

A) organic nitrogenous base 
B) pentose sugar 
C) phosphate 
D) sulfur 
A) organic nitrogenous base 
B) pentose sugar 
C) phosphate 
D) sulfur

Question 16

Genetic analysis indicates that an unknown organism contains a gene that codes for a defective form of telomerase.Based on this information alone,you can conclude that this organism

Accepted Answer

A) is prokaryotic. 
B) is eukaryotic. 
C) has unusually long telomeres. 
D) has an increased risk of developing cancer. 
A) is prokaryotic. 
B) is eukaryotic. 
C) has unusually long telomeres. 
D) has an increased risk of developing cancer.

Question 17

Why does DNA pol I carry the number one?

Accepted Answer

A) It was the first polymerase isolated from E.coli. 
B) It is the first polymerase to be activated during DNA replication. 
C) It is the only polymerase that has both 3' to 5' and 5' to 3' exonuclease activity. 
D) It is the smallest polymerase. 
A) It was the first polymerase isolated from E.coli. 
B) It is the first polymerase to be activated during DNA replication. 
C) It is the only polymerase that has both 3' to 5' and 5' to 3' exonuclease activity. 
D) It is the smallest polymerase.

Question 18

DNA replication always proceeds by adding new bases to the ________ end of an existing strand.

Accepted Answer

A) 1' 
B) 2' 
C) 3' 
D) 4' 
E) 5' 
A) 1' 
B) 2' 
C) 3' 
D) 4' 
E) 5'

Question 19

Which enzyme adds new nucleotides to the end of a growing strand?

Accepted Answer

A) ligase 
B) polymerase 
C) gyrase 
D) helicase 
E) endonuclease 
A) ligase 
B) polymerase 
C) gyrase 
D) helicase 
E) endonuclease

Question 20

Suppose a new species of bacterium is discovered.It contains a form of DNA pol III that can add new nucleotides to either the 5' end or the 3' end of an existing strand.All other properties of the enzyme remain unchanged.How would DNA replication in these bacteria differ from normal replication?

Accepted Answer

A) Both new strands could be synthesized continuously like the leading strand. 
B) The same polymerase molecule could synthesize both strands at the same time. 
C) Helicase would no longer be required for replication. 
D) DNA gyrase would no longer be required for replication. 
A) Both new strands could be synthesized continuously like the leading strand. 
B) The same polymerase molecule could synthesize both strands at the same time. 
C) Helicase would no longer be required for replication. 
D) DNA gyrase would no longer be required for replication.

Exam 14: Dna: the Genetic Material

Who originally discovered the process of bacterial transformation?

Which of the following statements about DNA replication is false?

An organism has been found to contain a defective form of photolyase.What function might be impaired in this organism?

Nucleotides have a phosphate group attached at the ________ carbon atom of the sugar.

The chemical bond connecting one nucleotide with the next along one strand of a DNA molecule is called a

The double helix model of DNA structure was proposed by

During DNA replication,each new strand begins with a short

If we think of the DNA double helix as a twisted ladder,what makes up the rungs or steps of the ladder?

After attaching to a bacterial cell,a bacteriophage typically

The synthesis of a growing strand of DNA is carried out by adding nucleotides to the ________ end of an existing strand.

Who demonstrated that phage genetic material is DNA and not protein?

Avery,MacLeod,and McCarty's experiments revealed that the transforming principle had all of the following properties except

Replication of DNA is

Which is not a component of nucleic acids?

Genetic analysis indicates that an unknown organism contains a gene that codes for a defective form of telomerase.Based on this information alone,you can conclude that this organism

Why does DNA pol I carry the number one?

DNA replication always proceeds by adding new bases to the ________ end of an existing strand.

Which enzyme adds new nucleotides to the end of a growing strand?

Suppose a new species of bacterium is discovered.It contains a form of DNA pol III that can add new nucleotides to either the 5' end or the 3' end of an existing strand.All other properties of the enzyme remain unchanged.How would DNA replication in these bacteria differ from normal replication?

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