Exam 16: Disruption of Healthy Tissue by the Adaptive Immune Response

The reason why babies born to mothers with Graves' disease suffer passively from the disease for only a short while after birth is that _____.

(Multiple Choice)

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Question 41

The autoreactive CD4 T cells of elderly people with rheumatoid arthritis _____.(Select all that apply.)

(Multiple Choice)

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Question 42

People who are heterozygous for HLA-DQ2 and HLA-DQ8 allotypes are at greater risk of developing type 1 diabetes than those who are homozygous for HLA-DQ2 or HLA-DQ8. A.Explain the reason for this increased susceptibility. B.Why is the above statement true mainly for people of northern European origin but not for some other ethnic groups?

(Essay)

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Question 43

Which of the following are correctly matched? (Select all that apply.)

(Multiple Choice)

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Question 44

Indicate whether each of the following statements is true (T)or false (F).

Ectopic lymphoid tissue resembling secondary lymphoid tissue may develop under the influence of lymphotoxin (LT).

False

Autoimmune responses are the result of innate immune responses directed toward self antigens.

True

Some forms of autoimmune disease involve IgE autoantibodies

Correct Answer:

Verified

Ectopic lymphoid tissue resembling secondary lymphoid tissue may develop under the influence of lymphotoxin (LT).

Autoimmune responses are the result of innate immune responses directed toward self antigens.

(Matching)

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Question 45

All of the following autoimmune diseases are correctly matched with their HLA disease associations except _____.

(Multiple Choice)

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Question 46

All of the following are characteristics of tissue transglutaminase except ____.

(Multiple Choice)

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Question 47

Explain the relationship between HLA-DRB1*04,smoking,the expression of peptidyl arginine deaminase,and rheumatoid arthritis.

(Essay)

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Question 48

Indicate whether each of the following statements is true (T)or false (F).

During pregnancy,IgG antibodies and activated lymphocytes can cross the placenta and enter the circulatory system of the fetus.

True

Newborns of mothers with T cell-mediated autoimmune diseases exhibit the same symptoms as their mothers.

False

Blood plasma exchange (plasmapheresis)can be used to remove maternal IgG from the newborn.

Correct Answer:

Verified

During pregnancy,IgG antibodies and activated lymphocytes can cross the placenta and enter the circulatory system of the fetus.

Newborns of mothers with T cell-mediated autoimmune diseases exhibit the same symptoms as their mothers.

(Matching)

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Question 49

Antagonistic autoantibodies made against the insulin receptor cause _____.(Select all that apply.)

(Multiple Choice)

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Question 50

Which of the following is associated with antagonistic autoantibodies against cell-surface receptors or adhesion molecules? (Select all that apply.)

(Multiple Choice)

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Question 51

You have isolated a subset of CD25⁺ CD4⁺ T cells from the blood that have T-cell receptors specific for a self antigen but do not proliferate when challenged with the antigen in vitro.What is the name given to these T cells,and what role are they thought to have in preventing autoimmunity?

(Essay)

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Question 52

It is believed that the allotype DRB1*_ may confer protection against rheumatoid arthritis because it contains _ amino acid residues at positions 70 and 71 that bind to different subsets of peptides compared with the allotypes that confer susceptibility to this disease.

(Multiple Choice)

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Question 53

The process by which the human thymus gradually decays is known as _____.

(Multiple Choice)

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Question 54

Which of the following is an example of a type II autoimmune response? (Select all that apply.)

(Multiple Choice)

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Question 55

The upregulation of _____ by IFN-γ can contribute to antigen-specific T-cell activation on thyroid epithelium.

(Multiple Choice)

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Question 56

Which type of autoimmune disease is correctly matched with its cause?

(Multiple Choice)

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Question 57

Bacterial infections are associated with which of the following autoimmune diseases? (Select all that apply.)

(Multiple Choice)

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Question 58

Which of the following is the cause of red blood cell deficiency in autoimmune hemolytic anemia? (Select all that apply.)

(Multiple Choice)

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Question 59

Which of the following is not a characteristic of Graves' disease?

(Multiple Choice)

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Question 60

Showing 41 - 60 of 64

The reason why babies born to mothers with Graves' disease suffer passively from the disease for only a short while after birth is that _____.

The autoreactive CD4 T cells of elderly people with rheumatoid arthritis _____.(Select all that apply.)

Which of the following are correctly matched? (Select all that apply.)

All of the following autoimmune diseases are correctly matched with their HLA disease associations except _____.

All of the following are characteristics of tissue transglutaminase except ____.

Explain the relationship between HLA-DRB1*04,smoking,the expression of peptidyl arginine deaminase,and rheumatoid arthritis.

Antagonistic autoantibodies made against the insulin receptor cause _____.(Select all that apply.)

Which of the following is associated with antagonistic autoantibodies against cell-surface receptors or adhesion molecules? (Select all that apply.)

You have isolated a subset of CD25⁺ CD4⁺ T cells from the blood that have T-cell receptors specific for a self antigen but do not proliferate when challenged with the antigen in vitro.What is the name given to these T cells,and what role are they thought to have in preventing autoimmunity?

It is believed that the allotype DRB1*_ may confer protection against rheumatoid arthritis because it contains _ amino acid residues at positions 70 and 71 that bind to different subsets of peptides compared with the allotypes that confer susceptibility to this disease.

The process by which the human thymus gradually decays is known as _____.

Which of the following is an example of a type II autoimmune response? (Select all that apply.)

The upregulation of _____ by IFN-γ can contribute to antigen-specific T-cell activation on thyroid epithelium.

Which type of autoimmune disease is correctly matched with its cause?

Bacterial infections are associated with which of the following autoimmune diseases? (Select all that apply.)

Which of the following is the cause of red blood cell deficiency in autoimmune hemolytic anemia? (Select all that apply.)

Which of the following is not a characteristic of Graves' disease?

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Cancer and Its Interactions With the Immune System

Filters

Exam 16: Disruption of Healthy Tissue by the Adaptive Immune Response

The reason why babies born to mothers with Graves' disease suffer passively from the disease for only a short while after birth is that _____.

The autoreactive CD4 T cells of elderly people with rheumatoid arthritis _____.(Select all that apply.)

Which of the following are correctly matched? (Select all that apply.)

All of the following autoimmune diseases are correctly matched with their HLA disease associations except _____.

All of the following are characteristics of tissue transglutaminase except ____.

Explain the relationship between HLA-DRB1*04,smoking,the expression of peptidyl arginine deaminase,and rheumatoid arthritis.

Antagonistic autoantibodies made against the insulin receptor cause _____.(Select all that apply.)

Which of the following is associated with antagonistic autoantibodies against cell-surface receptors or adhesion molecules? (Select all that apply.)

You have isolated a subset of CD25+ CD4+ T cells from the blood that have T-cell receptors specific for a self antigen but do not proliferate when challenged with the antigen in vitro.What is the name given to these T cells,and what role are they thought to have in preventing autoimmunity?

It is believed that the allotype DRB1*_____ may confer protection against rheumatoid arthritis because it contains _____ amino acid residues at positions 70 and 71 that bind to different subsets of peptides compared with the allotypes that confer susceptibility to this disease.

The process by which the human thymus gradually decays is known as _____.

Which of the following is an example of a type II autoimmune response? (Select all that apply.)

The upregulation of _____ by IFN-γ can contribute to antigen-specific T-cell activation on thyroid epithelium.

Which type of autoimmune disease is correctly matched with its cause?

Bacterial infections are associated with which of the following autoimmune diseases? (Select all that apply.)

Which of the following is the cause of red blood cell deficiency in autoimmune hemolytic anemia? (Select all that apply.)

Which of the following is not a characteristic of Graves' disease?

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Cancer and Its Interactions With the Immune System

Filters

You have isolated a subset of CD25⁺ CD4⁺ T cells from the blood that have T-cell receptors specific for a self antigen but do not proliferate when challenged with the antigen in vitro.What is the name given to these T cells,and what role are they thought to have in preventing autoimmunity?

It is believed that the allotype DRB1*_ may confer protection against rheumatoid arthritis because it contains _ amino acid residues at positions 70 and 71 that bind to different subsets of peptides compared with the allotypes that confer susceptibility to this disease.