Exam 10: Lipids

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Describe the differences between the glycosphingolipids corresponding to the A,B,and O human blood group antigens.

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The type O structure is found in all three glycosphingolipids.In both type A and type B,there is an added sugar;this sugar differs between type A and B.

What do all these compounds have in common: vitamin A,vitamin K,ubiquinone,and dolichol?

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They are all lipids with potent biological activities derived from isoprenoid precursors.

Which of the following is true of sphingolipids?

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A

Match the compounds on the left with the important roles they play listed on the right. (Answers are used only once.)
important component of myelin membranes
thromboxanes
mediates pain and inflammation
vitamin A
necessary for sight
sphingolipids
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Responses:
important component of myelin membranes
thromboxanes
mediates pain and inflammation
vitamin A
necessary for sight
sphingolipids
intra-tissue messengers
vitamin E
blood clotting
steroids
reducing agent
prostaglandins
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A compound containing N-acetylneuraminic acid (sialic acid)is:

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Identify the molecule(s)derived from sterols.

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Explain the cause of hereditary diseases of sphingolipid metabolism,such as Tay-Sachs and Niemann-Pick diseases.

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Which of the following statements concerning fatty acids is correct?

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Which of the following answers is not true?

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If beeswax,cholesterol,and phosphatidylglycerol were dissolved in chloroform,then subjected to thin-layer chromatography on silica gel using a mixture of chloroform/methanol/water as the developing solvent,which would move fastest?

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Which of the following best describes the cholesterol molecule?

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What is the most significant chemical difference between triacylglycerols and glycerophospholipids that leads to their different functions?

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Which of the following statements about membrane lipids is true?

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Tay-Sachs disease is the result of a genetic defect in the metabolism of:

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What is the effect of a double bond on fatty acid structure?

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Which of the following is not true of sterols?

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Which vitamin is derived from cholesterol?

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Draw the structure of phosphatidylserine in the ionic form it would have at pH 7.

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What are the chemical components of a biological wax,and what is their general structure?

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Match each of these vitamins with its biological role:
blood clotting
Vitamin D
Ca2+ and phosphate metabolism
Vitamin K
vision
Vitamin A
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Responses:
blood clotting
Vitamin D
Ca2+ and phosphate metabolism
Vitamin K
vision
Vitamin A
prevention of oxidative damage
Vitamin E
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