Question 1

Which of the following is a fundamental characteristic of the Notch pathway?

Accepted Answer

A) It works through nuclear signals involving the lac operon. 
B) It works through direct cell-to-cell contact. 
C) It allows mRNAs to accumulate in the posterior portion of the Drosophila embryo. 
D) It directs mRNAs to antisense systems in the posterior portion of all organisms. 
E) It provides symmetry to plant flowers. 
A) It works through nuclear signals involving the lac operon. 
B) It works through direct cell-to-cell contact. 
C) It allows mRNAs to accumulate in the posterior portion of the Drosophila embryo. 
D) It directs mRNAs to antisense systems in the posterior portion of all organisms. 
E) It provides symmetry to plant flowers.

Question 2

From a human developmental standpoint,what is the significance of Hox genes?

Accepted Answer

Hox genes are highly conserved among all

Question 3

What is the significance of the homeodomain?

Accepted Answer

The homeodomain is a highly conserved pr

Question 4

Segmentation genes,such as the pair-rule class,are inherited through mitochondrial DNA in Drosophila.

Accepted Answer

A) True 
 B)False

Question 5

Which general genetic process is believed to account for the variety of cellular structures and functions in eukaryotic cells?

Accepted Answer

A) variable gene activity 
B) negative control exclusively 
C) maternal environmental activities 
D) intron processing 
E) RNA processing 
A) variable gene activity 
B) negative control exclusively 
C) maternal environmental activities 
D) intron processing 
E) RNA processing

Question 6

Provide a brief description of the variable gene activity hypothesis as it relates to development.What information is often provided in support of this hypothesis?

Accepted Answer

Because all cells apparently have the sa

Question 7

Which class of genes controls the developmental identity of segments along the anterior-posterior axis?

Accepted Answer

The answer of Which class of genes controls the developmental...

Question 8

Immediately after fertilization of a Drosophila egg,the zygote nucleus undergoes a series of divisions.Subsequent nuclear migration generates a(n)________.

Accepted Answer

A) syncytial blastoderm 
B) maternal effect 
C) homeodomain 
D) zygote 
E) cleavage nucleus 
A) syncytial blastoderm 
B) maternal effect 
C) homeodomain 
D) zygote 
E) cleavage nucleus

Question 9

Which function earlier in development: maternal-effect genes or zygotic genes?

Accepted Answer

maternal-e

Question 10

Describe the relationship between the maternal-effect gene bicoid and the zygotic gene hunchback.

Accepted Answer

The bicoid protein is a transc

Question 11

Three investigators-Nusslein-Volhard,Wieschaus,and Lewis-won the Nobel Prize for physiology and medicine in 1995 for work they did in 1970 with Drosophila.Briefly describe their findings.

Accepted Answer

They identified and characteri

Question 12

In Drosophila,the sequential order of the function of segmentation genes is ________.

Accepted Answer

A) gap,segment-polarity,pair-rule 
B) pair-rule,transdeterminal,gap 
C) transdeterminal,gap,pair-rule 
D) gap,pair-rule,segment-polarity 
E) segmentational,helical,spherical 
A) gap,segment-polarity,pair-rule 
B) pair-rule,transdeterminal,gap 
C) transdeterminal,gap,pair-rule 
D) gap,pair-rule,segment-polarity 
E) segmentational,helical,spherical

Question 13

Genetic involvement in development appears to be achieved,at least in part,by variable gene activity.

Accepted Answer

A) True 
 B)False

Question 14

How does determination relate temporally to differentiation?

Accepted Answer

Determination occurs when a ce

Question 15

Differentiation is the process whereby a cell's determined state is expressed.

Accepted Answer

A) True 
 B)False

Question 16

What is the general order of genes involved in determining early Drosophila development?

Accepted Answer

maternal effect,gap,

Question 17

A gene that specifies the fate of a particular anatomical segment in Drosophila is called a(n)________.

Accepted Answer

The answer of A gene that specifies the fate of...

Question 18

Caenorhabditis elegans is extremely useful as an experimental organism because it has relatively few cells,and,for the most part,each embryonic cell's fate is developmentally fixed.

Accepted Answer

A) True 
 B)False

Question 19

It is presently believed that the asymmetric distribution of substances in the egg,positioned by the mother,is responsible for establishing the determined state.Which general term describes such molecular positioning?

Accepted Answer

internal m

Exam 20: Developmental Genetics

Which of the following is a fundamental characteristic of the Notch pathway?

From a human developmental standpoint,what is the significance of Hox genes?

What is the significance of the homeodomain?

Segmentation genes,such as the pair-rule class,are inherited through mitochondrial DNA in Drosophila.

Which general genetic process is believed to account for the variety of cellular structures and functions in eukaryotic cells?

Provide a brief description of the variable gene activity hypothesis as it relates to development.What information is often provided in support of this hypothesis?

Which class of genes controls the developmental identity of segments along the anterior-posterior axis?

Immediately after fertilization of a Drosophila egg,the zygote nucleus undergoes a series of divisions.Subsequent nuclear migration generates a(n)________.

Which function earlier in development: maternal-effect genes or zygotic genes?

Describe the relationship between the maternal-effect gene bicoid and the zygotic gene hunchback.

Three investigators-Nusslein-Volhard,Wieschaus,and Lewis-won the Nobel Prize for physiology and medicine in 1995 for work they did in 1970 with Drosophila.Briefly describe their findings.

In Drosophila,the sequential order of the function of segmentation genes is ________.

Genetic involvement in development appears to be achieved,at least in part,by variable gene activity.

How does determination relate temporally to differentiation?

Differentiation is the process whereby a cell's determined state is expressed.

What is the general order of genes involved in determining early Drosophila development?

A gene that specifies the fate of a particular anatomical segment in Drosophila is called a(n)________.

Caenorhabditis elegans is extremely useful as an experimental organism because it has relatively few cells,and,for the most part,each embryonic cell's fate is developmentally fixed.

It is presently believed that the asymmetric distribution of substances in the egg,positioned by the mother,is responsible for establishing the determined state.Which general term describes such molecular positioning?

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Modification of Mendelian Ratios

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Linkage and Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

DNA structure and Analysis

DNA Replication and Recombination

Chromosome Structure and DNA Sequence Organization

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,DNA Repair,and Transposition

Regulation of Gene Expression

The Genetics of Cancer

Recombinant DNA Technology

Genomics,Bioinformatics,and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Population and Evolutionary Genetics

Conservation Genetics

Filters