Exam 16: The Genetics of Cancer

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Define cancer at the anatomical level.

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List at least three environmental agents or factors that are known to cause cancer.

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What is the significance of CDK?

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Mutant versions of genes that are normally involved in promoting the cell cycle are known as ________.

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In what way can loss of heterozygosity lead to cancer?

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What is retinoblastoma,and what is its supposed genetic basis?

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The familial form of retinoblastoma is characterized by cancer appearing in both eyes relatively early in life.In contrast,the sporadic form is usually unilateral and appears later.What accounts for the difference?

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If someone has a predisposition to cancer,what genetic circumstance likely exists?

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