Question 1

Within the control region of the trp operon is a section of DNA that is sensitive to levels of tryptophan in the system.What is the name of this region?

Accepted Answer

leader or

Question 2

Approximately 5 percent of the cytosine residues are methylated in the genome of any given eukaryote.In what way is DNA methylation related to genetic regulation?

Accepted Answer

There is an inverse relationsh

Question 3

Alternative RNA splicing is a method that apparently evolved for the production of many different polypeptides from the same pre-mRNA.Provide an example of alternative splicing.

Accepted Answer

Various splicing schemes occur

Question 4

Alternative RNA processing generates different mRNAs that can direct the synthesis of different polypeptides.

Accepted Answer

A) True 
 B)False

Question 5

The trp and lac operons are both subject to forms of control that are typically called negative.

Accepted Answer

A) True 
 B)False

Question 6

Describe three characteristics of enhancers.

Accepted Answer

position need not be

Question 7

Describe what is meant by a gratuitous inducer.Give an example.

Accepted Answer

A gratuitous inducer is a chemical analo

Question 8

How are siRNA and miRNAs similar?

Accepted Answer

Although they arise from diffe

Question 9

Transcription in eukaryotes is generally influenced by enhancers,just as in prokaryotes.

Accepted Answer

A) True 
 B)False

Question 10

Describe the function and general nature of promoters in eukaryotes.

Accepted Answer

Promoter regions are necessary for the i

Question 11

Which of the following terms best characterizes catabolite repression associated with the lac operon in E.coli?

Accepted Answer

A) inducible system 
B) repressible system 
C) negative control 
D) positive control 
E) constitutive 
A) inducible system 
B) repressible system 
C) negative control 
D) positive control 
E) constitutive

Question 12

In what ways are eukaryotic transcription factors thought to function?

Accepted Answer

By binding to promoter and enhancer regi

Question 13

Two modular elements that appear as consensus sequences upstream from RNA polymerase II transcription start sites are ________.

Accepted Answer

A) microsatellites and transposons 
B) rDNA and nucleolar organizers 
C) TATA and CAAT 
D) TTAA and CCTT 
E) enhancers and telomeres 
A) microsatellites and transposons 
B) rDNA and nucleolar organizers 
C) TATA and CAAT 
D) TTAA and CCTT 
E) enhancers and telomeres

Question 14

Which of the following clusters of terms applies when addressing enhancers as elements associated with eukaryotic genetic regulation?

Accepted Answer

A) cis-acting,variable orientation,variable position 
B) trans-acting,fixed position,fixed orientation 
C) cis-acting,fixed position,fixed orientation 
D) cis-acting,variable position,fixed orientation 
E) trans- and cis-acting,variable position 
A) cis-acting,variable orientation,variable position 
B) trans-acting,fixed position,fixed orientation 
C) cis-acting,fixed position,fixed orientation 
D) cis-acting,variable position,fixed orientation 
E) trans- and cis-acting,variable position

Question 15

Which term refers to a contiguous genetic complex that is under coordinated control?

Accepted Answer

A) lysogen 
B) prototroph 
C) operon 
D) allosteric 
E) attenuation 
A) lysogen 
B) prototroph 
C) operon 
D) allosteric 
E) attenuation

Question 16

What experimental results would indicate that the mutation lacIs is dominant to lacI+?

Accepted Answer

In lacI^s / lacI⁺ parti

Question 17

Describe the general structure of a transcription factor.

Accepted Answer

Transcription factors are modu

Question 18

Describe how nucleosomes may influence gene transcription.

Accepted Answer

The binding of transcription factors req

Question 19

Name two consensus sequences or modular DNA sequences that may be found upstream from coding regions of some eukaryotic genes.

Accepted Answer

TATA and C

Question 20

What is the location of an enhancer in relation to the gene it affects?

Accepted Answer

The position of an enhancer ne

Exam 15: Regulation of Gene Expression

Within the control region of the trp operon is a section of DNA that is sensitive to levels of tryptophan in the system.What is the name of this region?

Approximately 5 percent of the cytosine residues are methylated in the genome of any given eukaryote.In what way is DNA methylation related to genetic regulation?

Alternative RNA splicing is a method that apparently evolved for the production of many different polypeptides from the same pre-mRNA.Provide an example of alternative splicing.

Alternative RNA processing generates different mRNAs that can direct the synthesis of different polypeptides.

The trp and lac operons are both subject to forms of control that are typically called negative.

Describe three characteristics of enhancers.

Describe what is meant by a gratuitous inducer.Give an example.

How are siRNA and miRNAs similar?

Transcription in eukaryotes is generally influenced by enhancers,just as in prokaryotes.

Describe the function and general nature of promoters in eukaryotes.

Which of the following terms best characterizes catabolite repression associated with the lac operon in E.coli?

In what ways are eukaryotic transcription factors thought to function?

Two modular elements that appear as consensus sequences upstream from RNA polymerase II transcription start sites are ________.

Which of the following clusters of terms applies when addressing enhancers as elements associated with eukaryotic genetic regulation?

Which term refers to a contiguous genetic complex that is under coordinated control?

What experimental results would indicate that the mutation lacIs is dominant to lacI+?

Describe the general structure of a transcription factor.

Describe how nucleosomes may influence gene transcription.

Name two consensus sequences or modular DNA sequences that may be found upstream from coding regions of some eukaryotic genes.

What is the location of an enhancer in relation to the gene it affects?

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Modification of Mendelian Ratios

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Linkage and Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

DNA structure and Analysis

DNA Replication and Recombination

Chromosome Structure and DNA Sequence Organization

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,DNA Repair,and Transposition

The Genetics of Cancer

Recombinant DNA Technology

Genomics,Bioinformatics,and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Developmental Genetics

Quantitative Genetics and Multifactorial Traits

Population and Evolutionary Genetics

Conservation Genetics

Filters

What experimental results would indicate that the mutation lacI^s is dominant to lacI⁺?