Exam 19: Amines

Provide the major organic product of the following reaction.

Circle the stronger base in the pair below, and briefly explain your choice.

What common names for 1,4-butanediamine and 1,5-pentanediamine are derived from their characteristic pungent odors?

Provide the structure of the major organic product in the reaction below.

Physostigmine is used in the treatment of glaucoma. Within this structure, the atom indicated by ________ is most basic, while atom ________ is least basic.

The following substrate is a starting material in the synthesis of compounds having opiod activity (J. Med. Chem. 2011, 957). Show all products that would result from the reaction below.

The nitrogen atom of trimethylamine is ________ hybridized which is reflected in the CNC bond angle of ________.

Provide the systematic name for the compound below.

Provide the structure of the major organic product in the reaction below.

Why are strongly acidic reagents inappropriate when attempting an electrophilic aromatic substitution with aniline?

Rank the following compounds in order of increasing boiling point (lowest to highest): triethylamine, cyclohexylamine, di-n-propylamine.

Pyridine does not undergo Friedel-Crafts reactions. Offer an explanation.

Provide the structure of the major organic product in the reaction below.

Provide the structure of the major organic product in the reaction below.

How might the presence of an N-H functionally be indicated using NMR spectroscopy?

Provide the structure of the major organic product in the reaction below.

The α-carbon atom bonded to the nitrogen of an alkylamine usually appears in what chemical shift (δ) range?

Circle the stronger base in the pair below, and briefly explain your choice.

Provide the IUPAC name of (CH₃)₃CCH₂CH₂NHCH₂CH₃.

When a 1° amine reacts with an alkyl sulfonyl chloride, the major organic product is ________.