Question 1

The nurse is providing information to a patient recently prescribed entacapone.Which statement is correct?

Accepted Answer

A)   This medication is not to be taken with carbidopa levodopa.
B)   Dosage is adjusted according to the patient's response.
C)   There will be fewer incidences of dopaminergic effects, such as confusion.
D)   This medication increases the production of dopamine in the brain. B

Question 2

Which cholinergic symptoms of Parkinson's disease are reduced with anticholinergic drugs?

Accepted Answer

A)   Cognitive impairments
B)   Rigidity
C)   Tremors and drooling
D)   Postural abnormalities C

Question 3

Dopamine agonists have been linked with which adverse effects in patients with Parkinson's disease?

Accepted Answer

A)   Oculogyric crisis
B)   Tardive dyskinesia
C)   Sudden sleep events
D)   Akathisia C

Question 4

The nurse is providing education to a patient recently placed on selegiline disintegrating tablets.Which statement by the patient indicates a need for further teaching?

Accepted Answer

A)   "This medication will help slow the development of symptoms."
B)   "I will place the tablet on my tongue before breakfast."
C)   "I may need to use a stool softener for constipation."
D)   "I should not push the tablet through the foil."

Question 5

What is the pharmacologic action of entacapone,a potent catechol O methyl transferase (COMT)inhibitor?

Accepted Answer

A)   Slows the deterioration of dopaminergic nerve cells
B)   Inhibits the relative excess of dopaminergic activity
C)   Reduces the destruction of dopamine in peripheral tissues
D)   Enhances the cholinergic symptoms of Parkinson's disease

Question 6

Parkinson's disease has which characteristic symptom(s)?(Select all that apply.)

Accepted Answer

A)   Muscle tremors
B)   Posture alterations
C)   Muscle flaccidity
D)   Tachycardia
E)   Slow body movement

Question 7

The nurse is teaching a patient with Parkinson's disease about levodopa.Which statement by the nurse is accurate regarding drug administration?

Accepted Answer

A)   "Take this medication in between meals."
B)   "Take this medication at bedtime to prevent dizziness."
C)   "Take this medication when your tremors get worse."
D)   "Take this medication with food or antacids to reduce GI upset."

Question 8

What is the rationale for administering levodopa instead of dopamine for treatment of Parkinson's disease?

Accepted Answer

A)   Dopamine does not cross the blood-brain barrier when administered orally.
B)   Levodopa is much less expensive.
C)   The half-life of dopamine is too short.
D)   Dopamine has too many reactions with other medications.

Question 9

Which adverse effects associated with levodopa therapy would support the nursing diagnosis risk for injury?

Accepted Answer

A)   Nausea and vomiting
B)   Orthostatic hypotension
C)   Anorexia and depression
D)   Tachycardia and palpitations

Question 10

When a patient taking a monoamine oxidase B inhibitor receives his dietary tray,the nurse knows to remove the

Accepted Answer

A)   cheese.
B)   eggs.
C)   bread.
D)   coffee.

Question 11

What point(s)should be included when teaching a patient about the use of apomorphine for treatment of Parkinson's disease?(Select all that apply.)

Accepted Answer

A)   The restoration of function resulting from stimulation of dopamine receptors is permanent.
B)   Apomorphine may be administered intravenously for rapid relief.
C)   Apomorphine does not have any opioid activity.
D)   A multidose injector pen is commonly used to administer apomorphine.
E)   You may experience nausea and vomiting, which can be treated with trimethobenzamide (Tigan) .F)  You may experience sleep attacks or episodes of daytime sleepiness.

Question 12

A patient taking rasagiline is assessed by the nurse to have a lasting significant increase in blood pressure.When reviewing the patient's current list of medications,the nurse decides to hold the next dose of

Accepted Answer

A)   dextromethorphan.
B)   levodopa.
C)   ciprofloxacin.
D)   Valium.

Question 13

Which vitamin will reduce the therapeutic effects of levodopa?

Accepted Answer

A)   A
B)   B6
C)   C
D)   D

Question 14

The nurse is preparing to begin administration of apomorphine to a patient.Before administering,the nurse will perform a baseline assessment of the patient's(Select all that apply.)

Accepted Answer

A)   mobility.
B)   orientation.
C)   intellectual ability.
D)   alertness.
E)   vital signs.

Question 15

The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago.The patient has a history of coronary artery disease and takes an antihypertensive and aspirin.Which information would support the need for a reduction in medication dosage by the health care provider?

Accepted Answer

A)   Constipation
B)   Brownish orange urine
C)   Drowsiness
D)   Dizziness

Exam 14: Drugs Used for Parkinson’s Disease