Question 1

The nurse recognizes that which factor(s)would contribute to digoxin toxicity in a 92-year-old patient?

Accepted Answer

A)   Taking the medication with meals
B)   Prolonged half-life of the drug digoxin
C)   Impaired renal function
D)   Diminished mental capacity B,C

Question 2

The nurse administers an initial dose of a steroid to a patient with asthma.Thirty minutes after administration,the nurse finds the patient agitated and stating that "everyone is out to get me." What is the term for this unusual reaction?

Accepted Answer

A)   Desired action
B)   Adverse effect
C)   Idiosyncratic reaction
D)   Allergic reaction C

Question 3

Which is the best description of when drug interactions occur?

Accepted Answer

A)   On administration of toxic dosages of a drug
B)   On an increase in the pharmacodynamics of bound drugs
C)   On the alteration of the effect of one drug by another drug
D)   On increase of drug excretion C

Question 4

When obtaining a patient's health history,which assessment data would the nurse identify as having the most effect on drug metabolism?

Accepted Answer

A)   History of liver disease
B)   Intake of a vegetarian diet
C)   Sedentary lifestyle
D)   Teacher as an occupation

Question 5

What occurs when two drugs compete for the same receptor site,resulting in increased activity of the first drug?

Accepted Answer

A)   Desired action
B)   Synergistic effect
C)   Carcinogenicity
D)   Displacement

Question 6

A physician's order indicates to administer a medication to the patient via the percutaneous route.The nurse can anticipate that the patient will receive this medication

Accepted Answer

A)   intramuscularly.
B)   subcutaneously.
C)   topically.
D)   rectally.

Question 7

The nurse administers 50 mg of a drug at 6:00 AM that has a half-life of 8 hours.What time will it be when 25 mg of the drug has been eliminated from the body?

Accepted Answer

A)   8:00 AM
B)   11:00 AM
C)   2:00 PM
D)   6:00 PM

Question 8

What do drug blood levels indicate?

Accepted Answer

A)   They confirm if the patient is taking a generic form of a drug.
B)   They determine if the patient has sufficient body fat to metabolize the drug.
C)   They verify if the patient is taking someone else's medications.
D)   They determine if the amount of drug in the body is in a therapeutic range.

Question 9

The nurse assesses which blood level to determine the amount of circulating medication in a patient?

Accepted Answer

A)   Peak
B)   Trough
C)   Drug
D)   Therapeutic

Question 10

Which statement(s)about liberation of drugs is/are true?

Accepted Answer

A)   A drug must be dissolved in body fluids before it can be absorbed into body tissues.
B)   A solid drug taken orally must disintegrate and dissolve in GI fluids to allow for absorption into the bloodstream for transport to the site of action.
C)   The process of converting the drug into a soluble form can be controlled to a certain degree by the dosage form.
D)   Converting the drug to a soluble form can be influenced by administering the drug with or without food in the patient's stomach.
E)   Elixirs take longer to be liberated from the dosage form.

Question 11

Which statement(s)about variables that influence drug action is/are true?

Accepted Answer

A)   An older adult will require increased dosage of a drug to achieve the same therapeutic effect as that seen in a younger person.
B)   Body weight can affect the therapeutic response of a medication.
C)   Chronic smokers may metabolize drugs more rapidly than nonsmokers.
D)   A patient's attitude and expectations affect the response to medication.
E)   Reduced circulation causes drugs to absorb more rapidly.

Question 12

A nurse is preparing to administer tetracycline to a patient diagnosed with an infection.Which medication should not be administered with tetracycline?

Accepted Answer

A)   Ativan
B)   Tylenol
C)   Colace
D)   Mylanta

Question 13

A patient receives 200 mg of a medication that has a half-life of 12 hours.How many mg of the drug would remain in the patient's body after 24 hours?

Accepted Answer

The answer of A patient receives 200 mg of a...

Question 14

What will the nurse need to determine first in order to mix two drugs in the same syringe?

Accepted Answer

A)   Absorption rate of the drugs
B)   Compatibility of the drugs
C)   Drug blood level of each drug
D)   Medication adverse effects

Question 15

Which factor(s)affect(s)drug actions?

Accepted Answer

A)   Teratogenicity
B)   Age
C)   Body weight
D)   Metabolic rate
E)   Illness

Question 16

A patient developed hives and itching after receiving a drug for the first time.Which instruction by the nurse is accurate?

Accepted Answer

A)   Stop the medication and encourage the patient to wear a medical alert bracelet that explains the allergy.
B)   Explain to the patient that these are signs and symptoms of an anaphylactic reaction.
C)   Emphasize to the patient the importance to inform medical personnel that in the future a lower dosage of this drug is necessary.
D)   Instruct the patient that it would be safe to take the drug again because this instance was a mild reaction.

Question 17

The nurse assesses hives in a patient started on a new medication.What is the nurse's priority action?

Accepted Answer

A)   Notify physician of allergic reaction.
B)   Notify physician of idiosyncratic reaction.
C)   Notify physician of potential teratogenicity.
D)   Notify physician of potential tolerance.

Question 18

Which route(s)enable(s)drug absorption more rapidly than the subcut route?

Accepted Answer

A)   IV route
B)   IM route
C)   Inhalation/sublingual
D)   Intradermal route
E)   Enteral route

Question 19

What is the process by which a drug is transported by circulating body fluids to receptor sites?

Accepted Answer

A)   Osmosis
B)   Distribution
C)   Absorption
D)   Biotransformation

Question 20

Which are routes of drug excretion?

Accepted Answer

A)   GI tract; feces
B)   Genitourinary (GU)  tract; urine
C)   Lymphatic system
D)   Circulatory system; blood/plasma
E)   Respiratory system; exhalation

Exam 2: Basic Principles of Drug Action and Drug Interactions

The nurse recognizes that which factor(s) would contribute to digoxin toxicity in a 92-year-old patient?