A 34-Year-Old Man Comes to the Physician for a Follow-Up

A 34-year-old man comes to the physician for a follow-up examination. One month ago, he underwent splenectomy after being involved in a motor vehicle collision. He recovered uneventfully and was discharged. He received the recommended vaccinations after her surgery and currently feels well.  Physical examination shows no abnormalities.  A peripheral blood smear reveals many red blood cells of a specific morphology as indicated by the arrow below. An increase in which of the following features best explains the presence of these abnormal cells?

A) Aggregated iron deposits
B) Clusters of remnant DNA
C) Denatured hemoglobin
D) Fragility to osmotic stress
E) Precipitated ribosomes
F) Surface area-to-volume ratio

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