A 60-Year-Old Man Comes to the Office for a Significant

A 60-year-old man comes to the office for a significant increase in the size of his breasts. He has a history of obstructive urinary symptoms due to benign prostatic hyperplasia that were unrelieved with tamsulosin, and a new medication was prescribed at his last visit 8 months ago.  Since starting the new medication, the patient has experienced gradual improvement in urinary hesitancy and strength of urinary stream.  The patient reports no pain or changes in weight.  Glandular tissue, approximately 2 cm in diameter, is palpated under the nipples and is mildly tender to palpation.  There is no nipple discharge, breast asymmetry, or rash.  This patient's breast findings are most likely due to which of the following drug effects?

A) Blockade of androgen receptors
B) Decreased testicular production of testosterone
C) Displacement of estrogen from sex hormone-binding globulin
D) Increased peripheral conversion of testosterone to estradiol
E) Increased prolactin production

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free