Researchers Are Studying the Structure and Function of Hemoglobin

Researchers are studying the structure and function of hemoglobin.  Arterial and venous blood samples are obtained from enrolled volunteers with no health problems.  Red blood cells are isolated from whole blood by differential centrifugation, and the contents of the intact red blood cells are analyzed.  It is found that the concentration of chloride is much lower in the red blood cells in the arterial sample compared to the venous sample.  The activity of which of the following enzymes is most likely responsible for the observed finding?

A) Bisphosphoglycerate mutase
B) Carbonic anhydrase
C) Glucose-6-phosphate dehydrogenase
D) Na⁺-K⁺ ATPase
E) Pyruvate kinase

Correct Answer:

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