A 15-Year-Old Boy Is Brought to the Office by His

A 15-year-old boy is brought to the office by his mother due to difficulty with movement.  The patient enjoys playing high school basketball but had to leave the team this year due to his progressively worsening symptoms.  On examination, he is found to have significant kyphoscoliosis and a high plantar arch.  His older brother suffered from a neurologic disorder and died of heart failure at age 25.  This patient most likely has which of the following neuropathologic findings?

A) Atrophy of the caudate nucleus
B) Cerebral cortex atrophy
C) Degeneration of the spinocerebellar tracts
D) Demyelination of peripheral nerves
E) Loss of neurons in the anterior horn of the spinal cord
F) Loss of neurons in the substantia nigra

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