A 34-Year-Old Man Is Evaluated for Elevated Liver Aminotransferases

A 34-year-old man is evaluated for elevated liver aminotransferases.  The patient has no chronic medical conditions but has a history of injection drug use.  Family history is notable for liver cirrhosis in his mother.  Ultrasonography-guided liver biopsy is performed.  Histopathology demonstrates marked panlobular mononuclear cell infiltration that cross into adjacent lobules.  Occasional intensely eosinophilic round bodies are seen scattered amongst the hepatic parenchyma.  Which of the following is the most likely cause of the latter histopathological finding in this patient?

A) Coagulative necrosis due to a toxin
B) Cytotoxic T-cell-mediated apoptosis
C) Intracellular pigment accumulation
D) Intracytoplasmic cytokeratin deposition
E) Small foci of fibrinoid necrosis
F) Stellate cell activation into myofibroblast

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free