A 32-Year-Old Man Comes to the Office Due to Progressive

A 32-year-old man comes to the office due to progressive fatigue, easy bruising, and recurring episodes of gum bleeding.  Physical examination shows several ecchymoses in his lower extremities.  Laboratory studies are as follows: Bone marrow biopsy is performed and fluorescence in situ hybridization studies reveal a balanced translocation between the long arms of chromosomes 15 and 17.  Which of the following proteins is most likely to be abnormal in the hematopoietic cells of this patient?

A) Epidermal growth factor receptor
B) GTP-binding protein
C) Platelet-derived growth factor receptor
D) Retinoblastoma gene product
E) Retinoic acid receptor

Correct Answer:

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