A 38-Year-Old Woman Suddenly Collapses at Home After Experiencing Severe

A 38-year-old woman suddenly collapses at home after experiencing severe chest pain and dies before reaching a hospital.  Postmortem examination reveals an occluding thrombus overlying a ruptured atherosclerotic plaque on the left anterior descending artery.  The patient is also found to have thickened mitral valve leaflets with multiple small vegetations on both valvular surfaces and fibrinoid necrosis of arterioles.  Other findings include glomerular capillary basement membrane thickening with wire-loop changes.  This patient was most likely suffering from which of the following conditions?

A) Bacterial endocarditis
B) Churg-Strauss syndrome
C) Granulomatosis with polyangiitis
D) Systemic lupus erythematosus
E) Thromboangiitis obliterans

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