Certain Patients with Non-Small Cell Lung Cancer Develop Constitutive Tumor

Certain patients with non-small cell lung cancer develop constitutive tumor kinase activity due to the production of echinoderm microtubule-associated protein-like 4 - anaplastic lymphoma kinase (EML4-ALK) , a fusion protein that contributes to carcinogenesis.  This is most similar to the molecular pathophysiology of which of the following disorders?

A) Burkitt lymphoma
B) Chronic myelogenous leukemia
C) Follicular lymphoma
D) Li-Fraumeni syndrome
E) Mantle cell lymphoma

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