A 10-Year-Old Boy Is Brought to the Hospital for Difficulty

A 10-year-old boy is brought to the hospital for difficulty swallowing.  During dinner a few hours ago, a piece of chicken became stuck in the patient's mid-chest region.  His parents say that he has previously had the sensation of food becoming stuck, but it has never lasted this long.  The patient has vomited multiple times, but the chicken has not dislodged.  Medical history is significant for eczema.  He is drooling and visibly uncomfortable.  An upper endoscopy is performed to remove the chicken from the esophagus, which exhibits multiple stacked, circular, ringlike indentations; linear furrowing; and scattered, small, whitish papules.  Which of the following findings is most likely to be seen on biopsy of this patient's esophagus?

A) Eosinophilic infiltration of the esophageal mucosa
B) Ganglionic degeneration within the myenteric plexus
C) Intestinal metaplasia of the esophageal epithelium
D) Replacement of the esophagus with fibrous tissue
E) Squamous cells with eosinophilic intranuclear inclusions

Correct Answer:

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