A 21-Year-Old Woman Comes to the Office Due to Recurrent

A 21-year-old woman comes to the office due to recurrent episodes of self-limited, colicky abdominal pain.  She also had an episode of facial swelling that resolved spontaneously.  The patient has no other significant past medical history and takes no medications.  Examination is unremarkable.  Evaluation shows that her complement protein C1, even when not attached to an antigen-antibody complex, is excessively cleaving C2 and C4.  Which of the following is most likely increased in this patient?

A) Antinuclear antibody titer
B) Antistreptolysin O titer
C) Bradykinin
D) Free hemoglobin
E) Renin

Correct Answer:

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