A 63-Year-Old Man Comes to the Office Due to Several

A 63-year-old man comes to the office due to several months of dysphagia, fatigue, occasional chest discomfort, and indigestion.  He has a history of hypertension and takes amlodipine.  The patient smokes 1 or 2 cigars daily.  His blood pressure is 140/80 mm Hg.  Physical examination is normal.  An endoscopic evaluation with esophageal biopsy is performed.  The histopathology of the specimen is shown in the image below. Which of the following is the most likely cause of this patient's dysphagia?

A) Benign tumor with slow growth
B) Malignancy with probable poor prognosis
C) Metaplasia with increased risk of adenocarcinoma
D) Motor dysfunction with increased risk of carcinoma
E) Reflux esophagitis with high risk of metaplasia

Correct Answer:

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