A 20-Year-Old Student Collapses Suddenly in Class and Dies, Despite

A 20-year-old student collapses suddenly in class and dies, despite resuscitation efforts.  Review of the medical chart is conducted-including symptoms, review of systems, medical history, and substance use-and is unremarkable except for a family history of sudden cardiac death.  Autopsy is performed and myocardial histology is shown in the image.  Complete genotyping is most likely to reveal a pathologic mutation that affects a protein belonging to which of the following structures?

A) Cell junction complex
B) Ion channel
C) Mitochondria
D) Nuclear envelope
E) Sarcomere

Correct Answer:

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