A Study Is Conducted to Assess Whether Quantitative Measurement of Heat

A study is conducted to assess whether quantitative measurement of heat shock protein 90 alpha (Hsp90α) in plasma can improve diagnostic accuracy and help monitor treatment response in liver cancer patients.  A total of 300 individuals (100 liver cancer patients and 200 healthy controls) participate in the study.  Analyses reveal that 90 of the liver cancer patients have an abnormally high plasma Hsp90α level and that 12 of the healthy controls have an abnormally high plasma Hsp90α level.  An abnormally high plasma Hsp90α level indicates a positive test for liver cancer.  Which of the following values best represents the specificity of this test?

A) 6%
B) 10%
C) 33%
D) 90%
E) 94%

Correct Answer:

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