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A Group of Researchers Conducted a Case-Control Study to Estimate

Question 63

Multiple Choice

A group of researchers conducted a case-control study to estimate the association between exposure to a certain pesticide and head and neck squamous cell carcinomas.  Controls were matched to cases by age and gender.  Exposure status was determined by interviewing the subjects.  On matched-pair analysis, the odds ratio is 7.5 (95% confidence interval: 2.3-14.8) .  Based on this information, which of the following is most likely to affect the validity of this study?


A) Confounding bias by age
B) Healthy worker bias
C) Misclassification bias
D) Nonresponse bias
E) Placebo effect

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